Brunner Lab

Publications

Lam, E; Berezny, K; Bishop, CJ; Lomax, KG; Liva, SG; Brunner, HI; Paller, AS; Diaz, LZ; Lee, LW; Rubin, C; Majlessi, A; Smith, V; Zhang, R; Leu, JH. Pharmacokinetics and Safety of Ustekinumab in Patients with Juvenile Psoriatic Arthritis: Results of the Real-World Ustekinumab Pediatric Opportunistic Pharmacokinetics Study (U-POPS). Rheumatology and Therapy. 2026; 13(1):265-278.

O'connor, SK; Devarajan, P; Liu, J; Maldonado, MA; Sproles, A; Rose, J; Thornton, S; Chen, C; Huang, B; Brunner, HI. The Renal Activity Index for Lupus: Validation for Prediction of Kidney Inflammation in Adult Patients With Lupus Nephritis. Journal of Rheumatology. 2026.

Shahin, MM; Gorell, ES; Iqneibi, M; Sun, Q; Brunner, HI; Hellmann, J; Marathe, KS. Characterization of TNF-Alpha Inhibitor Induced Paradoxical Psoriasiform Dermatitis at a Single Center via Retrospective Chart Review. Pediatric Dermatology. 2026; 43(1):84-87.

Weiss, PF; Ruperto, N; Quebe-Fehling, E; Shew, A; Pricop, L; Pieterse, CC; Brunner, HI. Juvenile Spondyloarthritis Disease Activity Index Validation in Enthesitis-Related Arthritis and Juvenile Psoriatic Arthritis in a Prospective Clinical Trial Setting. Journal of Rheumatology. 2026; 53(1):85-94.

Cunningham, NR; Senger-Carpenter, T; Zuckerman, J; Adler, M; Reid, MR; Danguecan, A; Pereira, LF; Mossad, SI; Ely, SL; Abulaban, K; Brunner, HI; Reeves, M; Pierce, SJ; Knight, A. Cognitive Behavioral Therapy for Youth with Childhood-Onset Lupus: A Randomized Clinical Trial. Arthritis Care and Research. 2025.

Vega-Fernandez, P; Avar-Aydin, PO; Rogers, K; Lovell, DJ; Huggins, J; Grom, A; Brunner, HI; Schulert, GS; Angeles-Han, ST; Altaye, M; Cassedy, A; Meyers, AB; Ting, TV. Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children with Juvenile Idiopathic Arthritis. Arthritis Care and Research. 2025.

Brunner, HI; Antón, J; Calvo-Penadés, I; Dimelow, R; Horneff, G; Kamphuis, S; Marino, R; Van Maurik, A; Minden, K; Mori, M; Ocran-Appiah, J; Wilkinson, C; Yamasaki, Y; Assudani, D. Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open-Label Trial. Arthritis Care and Research. 2025.

Sammaritano, LR; Askanase, A; Bermas, BL; Dall'era, M; Duarte-García, A; Hiraki, LT; Son, MBF; Werth, VP; Aranow, C; Barnado, A; Turgunbaev, M; Williams, JN; Turner, AS; Mustafa, RA. 2025 American College of Rheumatology (ACR) Guideline for the Treatment of Systemic Lupus Erythematosus. Arthritis & Rheumatology. 2025.

Sammaritano, LR; Askanase, A; Bermas, BL; Dall'era, M; Duarte-García, A; Hiraki, LT; Son, MBF; Werth, VP; Aranow, C; Barnado, A; Turgunbaev, M; Williams, JN; Turner, AS; Mustafa, RA. 2025 American College of Rheumatology (ACR) Guideline for the Treatment of Systemic Lupus Erythematosus. Arthritis Care and Research. 2025.

Yung, EM; Fridley, A; Matheny, T; Brunner, HI. Navigating the Biosimilars from Bench to Bedside in Juvenile Idiopathic Arthritis. Paediatric Drugs. 2025; 27(6):679-691.

Brunner, HI; Alexeeva, E; Bandeira, M; Carrasco, R; Chaitow, J; Chiraseveenuprapund, P; Ting, TV; Erguven, M; Gottlieb, B; Oliveira, SK; Stockert, L; Martini, A; Lovell, DJ; Ruperto, N. Tofacitinib for the Treatment of Juvenile Idiopathic Arthritis: Patient-Reported Outcomes in a Phase 3, Randomized, Double-Blind, Placebo-Controlled Withdrawal Trial. Arthritis & Rheumatology. 2025.

Romankevych, I; Singer, N; Huggins, J; Marathe, K; Merritt, A; Chen, C; Stockert, L; Pelletier, K; Wang, X; Shi, H; Huang, B; Brunner, H. Pharmacokinetics, effectiveness, tolerability and effect on quality of life of open-label tofacitinib for the treatment of moderately active mucocutaneous manifestations of SLE: results of a 76-week phase II study. Lupus Science and Medicine. 2025; 12(2).

Brunner, HI; Cody, EM; Devarajan, P; Huang, B; Chen, C; Sinibaldi, D; Ramaswamy, M; Knagenhjelm, J; Jones, F; Brohawn, PZ; Tummala, R; Lindholm, C; White, WI. The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis. Arthritis Care and Research. 2025.

Correll, C; Burciu, A; Bansal, A; Dennos, A; Narayanswamy, D; Aubrun, E; Schanberg, LE; Yuhan, L; Schneider, R; Balevic, S; Kimura, Y; Beukelman, T. Long-term safety of canakinumab in patients with systemic juvenile idiopathic arthritis: 5-year results from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry. Pediatric Rheumatology. 2025; 23(1):105.

Ringold, S; Ong, M-S; Tomlinson, G; Natter, MD; Schanberg, LE; Del Gaizo, V; Feldman, BM; Murphy, KL; Kimura, Y. Three-Year Outcomes and Latent Class Trajectory Analysis of the Childhood Arthritis and Rheumatology Research Alliance Polyarticular JIA Consensus Treatment Plans Study. Arthritis & Rheumatology. 2025; 77(10):1433-1441.

Ruperto, N; Lovell, DJ; Synoverska, O; Abud-Mendoza, C; Spindler, A; Vyzhga, Y; Reyhan, I; Grebenkina, L; Tirosh, I; Imundo, L; Ebrahim, A; Klaus, P; Martini, A; Brunner, HI. Impact of Concomitant Methotrexate Use and Prior Biologic Disease-Modifying Antirheumatic Drug Exposure on Tofacitinib Efficacy and Safety in Patients with Polyarticular Course Juvenile Idiopathic Arthritis: Post Hoc Analysis of a Phase 3 Randomized Withdrawal Trial. ACR Open Rheumatology. 2025; 7(10):e70097.

Mönkemöller, K; Weber, LT; Häusler, M; Kallinich, T; Benseler, S; Brunner, HI; Bieber, C; Brunner, J; Deuter, C; Hahn, G; Tönshoff, B; Tenbrock, K; Haffner, D; Schuetz, C. Interdisciplinary Clinical Practice Guidelines for patient-centred management of juvenile-onset systemic lupus erythematosus. EULAR Rheumatology Open. 2025; 1(4):380-393.

Sammaritano, LR; Askanase, A; Bermas, BL; Dall'era, M; Duarte-García, A; Hiraki, LT; Rovin, BH; Son, MBF; Alvarado, A; Aranow, C; Turgunbaev, M; Williams, JN; Turner, AS; Mustafa, RA. 2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis. Arthritis Care and Research. 2025; 77(9):1045-1065.

Consolaro, A; Ruperto, N; Lovell, DJ; Synoverska, O; Abud-Mendoza, C; Spindler, A; Vyzhga, Y; Alexeeva, E; Chaitow, J; Chiraseveenuprapund, P; Lazariciu, I; Stockert, L; Cadatal, MJ; Diehl, A; Brunner, HI. Clinically Inactive Disease and Remission in Patients With Juvenile Idiopathic Arthritis Receiving Tofacitinib: Post Hoc Analysis of a Phase III Trial. Journal of Rheumatology. 2025; 52(9):919-926.

Sammaritano, LR; Askanase, A; Bermas, BL; Dall'era, M; Duarte-García, A; Hiraki, LT; Rovin, BH; Son, MBF; Alvarado, A; Aranow, C; Turgunbaev, M; Williams, JN; Turner, AS; Mustafa, RA. 2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis. Arthritis & Rheumatology. 2025; 77(9):1115-1135.

Rypdal, V; Brunner, HI; Feldman, BM; Ruperto, N; Aggarwal, A; Angeles-Han, ST; Backström, M; Balay-Dustrude, E; Bracaglia, C; De Benedetti, F; Vojinovic, J; Weiss, PF; Gottlieb, B; Consolaro, A. Physician's global assessment of disease activity in juvenile idiopathic arthritis: consensus-based recommendations from an international task force. Annals of the Rheumatic Diseases. 2025; 84(8):1425-1436.

Mannion, ML; Aswani, MS; Hearld, KR; Smitherman, EA; Timmerman, L; Curtis, JR. Disease activity at two consecutive registry visits and subsequent medication escalation for patients with juvenile idiopathic arthritis in the CARRA registry. Pediatric Rheumatology. 2025; 23(1):77.

Nguyen, K; Yasin, S; Fall, N; Grom, AA; Brunner, HI; Towe, C; Schulert, GS. Utility of patient-reported outcomes for pulmonary symptoms and sleep disturbance and impairment in children with systemic juvenile idiopathic arthritis. Pediatric Rheumatology. 2025; 23(1):74.

Zhao, J; Zhao, X; Mizuno, T; Irie, K; Devarajan, P; Brunner, HI; Setchell, KDR. Volumetric Absorptive Microsampling Combined with Mass Spectrometry to Support Pharmacokinetically-Guided Precision Dosing of Mycophenolate Mofetil in Pediatric Lupus Nephritis Patients. Journal of Applied Laboratory Medicine. 2025; 10(4):806-819.

Cody, EM; Sproles, A; Rose, J; Huang, B; Devarajan, P; Brunner, HI; Thornton, S. Development and Validation of Multiplex Assays for Lupus Nephritis Activity Biomarkers. Kidney International Reports. 2025; 10(7):2255-2264.

Arnaud, L; Ruiz-Irastorza, G; Aranow, C; Bernatsky, S; Dall'era, M; Adelowo, O; Bae, S-C; Beretta, L; Bonfa, E; Cervera, R; Gerosa, M; Touma, Z; Mosca, M; Tani, C. ERN ReCONNET-SLICC-SLEuro expert consensus on the therapeutic management of rare systemic lupus erythematosus manifestations. The Lancet Rheumatology. 2025; 7(7):e505-e518.

Ohnishi, T; Wilkerson, J; Bayat, N; Farhadi, PN; Faiq, A; Dillon, CF; Schiffenbauer, A; Parks, CG; Brunner, HI; Goldberg, B; Miller, FW; Rider, LG. Infections preceding diagnosis associated with myositis phenotypes in a national patient registry. Clinical and Experimental Rheumatology. 2025; 43(7):1204-1212.

Difrancesco, M; Wilson, E; Brunner, H. POS1400 PERIVENTRICULAR ABNORMALITY GRADIENTS OF RELAXOMETRY AND SUSCEPTIBILITY METRICS BY NEUROIMAGING: COMPARING LUPUS AND MULTIPLE SCLEROSIS. Annals of the Rheumatic Diseases. 2025; 84:1421-1422.

Kasap-Cuceoglu, M; Huggins, J; Ting, T; Smith-Rodriguez, J; Merritt, A; Brunner, H. POS1172 EVALUATING THE STANDARDIZED STEROID REGIMEN (SSR) FOR CHILDHOOD-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RETROSPECTIVE INSIGHTS FROM REAL-WORLD DATA. Annals of the Rheumatic Diseases. 2025; 84:1242-1243.

Estel, GJP; Quintana, R; Nieto, R; Brunner, H; Scolnik, M; Soaje, CF; Alba, P; Saurit, V; García, MA; Berbotto, G; Zazzetti, F; Orillion, A; Sbarigia, U; Pons-Estel, B. POS0841 THE RENAL ACTIVITY INDEX FOR LUPUS IDENTIFIES AND PREDICTS COMPLETE RENAL REMISSION OR ABSENCE OF KIDNEY INVOLVEMENT IN SYSTEMIC LUPUS ERYTHEMATOSUS. Annals of the Rheumatic Diseases. 2025; 84:985-986.

Vega-Fernandez, P; Huggins, J; Angeles-Han, S; Lovell, DJ; Brunner, H; Rogers, K; Quinlan-Waters, M; Thornton, S; Cassedy, A; Ting, T. POS0295 RELATIONSHIP AMONG A PEDIATRIC-SPECIFIC ULTRASOUND SCORING SYSTEM FOR THE EVALUATION OF ARTHRITIS AND BIOLOGIC MARKERS OF INFLAMMATION. Annals of the Rheumatic Diseases. 2025; 84:556.

Ruperto, N; Li, C; Chinniah, K; Uziel, Y; Synoverska, O; Sawhney, S; Calvo, I; Louw, I; Lu, M; Patel, PN; Koch, GG; Martini, A; Lovell, DJ; Brunner, H. OP0212 EFFICACY AND SAFETY OF TOFACITINIB IN PATIENTS WITH ACTIVE SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS. Annals of the Rheumatic Diseases. 2025; 84:176-177.

Difrancesco, M; Brunner, H. VOLUME AND DYNAMIC BLOOD FLOW OF THE CHOROID PLEXUS IN NEUROINFLAMMATORY DISEASE. Journal of Rheumatology. 2025; 52(Suppl 1):106-107.

Barraclough, M; Mckie, S; Rittner, L; Knight, A; Katz, P; Hanly, J; Legge, A; Mackay, M; Dobrowolski, C; Brunner, H; Parker, B; Bruce, I; Touma, Z; Appenzeller, S. INTERNATIONAL EFFORT IN HARMONIZING COGNITIVE IMPAIRMENT RESEARCH IN SYSTEMIC LUPUS ERYTHEMATOSUS. Journal of Rheumatology. 2025; 52(Suppl 1):39-40.

Connelly, K; Koelmeyer, R; Ayton, D; May, J; Gregory, K; Eades, LE; Barallon, R; Kandane-Rathnayake, R; Golder, V; Anzum, A; Furie, RA; Van Vollenhoven, RF; Banerjee, S; Morand, E. Domains for inclusion in a novel Treatment Response Measure for Systemic Lupus Erythematosus (TRM-SLE): results of a modified Delphi study. Lupus Science and Medicine. 2025; 12(1).

Maccora, I; Altaye, M; Greis, KD; Brunner, HI; Duell, A; Haffey, WD; Nguyen, T; Quinlan-Waters, M; Schulert, GS; Sproles, A; Utz, VM; Thornton, S; Angeles-Han, ST. Candidate Tear-Based Uveitis Biomarkers in Children with JIA Based on Arthritis Activity and Topical Corticosteroid Use. Ocular Immunology and Inflammation. 2025; 33(4):603-612.

Brunner, HI; Shmagel, A; Horneff, G; Foeldvari, I; Antón, J; Ramanan, AV; Qian, Y; Unnebrink, K; Hao, S; Camp, HS; Khan, N; Liu, W; Mohamed, M-EF. Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular-Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open-Label, Phase 1 Trial. Arthritis Care and Research. 2025; 77(5):584-593.

Macaraeg, M; Baker, E; Handorf, E; Matt, M; Baker, EK; Brunner, H; Grom, AA; Henrickson, M; Huggins, J; Zhang, W; Lee, P; Marsh, R; Schulert, GS. Clinical, Immunologic, and Genetic Characteristics in Patients With Syndrome of Undifferentiated Recurrent Fevers. Arthritis & Rheumatology. 2025; 77(5):596-605.

Shishov, M; Weiss, PF; Levy, DM; Chang, JC; Angeles-Han, ST; Ogbu, EA; Nanda, K; Sherrard, TM; Goldmuntz, E; Lovell, DJ; Rider, LG; Brunner, HI. 25 Years of Biologics for the Treatment of Pediatric Rheumatic Disease: Advances in Prognosis and Ongoing Challenges. Arthritis Care and Research. 2025; 77(5):573-583.

Eloseily, E; Pickering, A; Dhakal, S; Ruperto, N; Brunner, HI; Grom, AA; Thornton, S. Transcriptional Profiling of Tofacitinib Treatment in Juvenile Idiopathic Arthritis: Implications for Treatment Response Prediction. Arthritis Care and Research. 2025; 77(4):513-521.

Hamdi, W; Migowa, A; Ferjani, HL; Makhloufi, CD; Makhlouf, Y; Nasef, SI; Ziade, N; Baraliakos, X; Brunner, H; Hassan, M; Furia, FF; Slimani, S; Scott, C; Hadef, D. Pediatric Society of the African League Against Rheumatism juvenile idiopathic arthritis recommendations for enthesitis-related arthritis and juvenile psoriatic arthritis. Clinical Rheumatology. 2025; 44(3):901-922.

Sadun, RE; Cooper, JC; Belot, A; Avcin, T; Aggarwal, A; Ainsworth, J; Akinsete, A; Ardoin, SP; Beresford, MW; Bortey, L; Wenderfer, SE; Woodside, A; Lewandowski, LB; Smith, EM. Development of CARRA/PReS-endorsed consensus Core and Expanded Datasets in childhood-onset systemic lupus erythematosus for international registry-based research. Annals of the Rheumatic Diseases. 2025; 84(2):158-168.

Li, Y; Huang, B; Andorf, S; Yue, X; Lovell, DJ; Brunner, HI. Comparative Effectiveness and Safety of the JAK Inhibitors and Biologic Disease-Modifying Antirheumatic Drugs in Treating Children With Nonsystemic Juvenile Idiopathic Arthritis: A Bayesian Meta-Analysis of Randomized Controlled Trials. ACR Open Rheumatology. 2025; 7(2):e11788.

Ogbu, EA; Sagcal-Gironella, ACP; Eberhard, BA; Huggins, JM; Klein-Gitelman, MS; Onel, K; Chen, C; Huang, B; Brunner, HI. Implementation of the Lupus Low Disease Activity State in Pediatric Rheumatology Care: The Role of the Visual Analog Scale. ACR Open Rheumatology. 2025; 7(1):e11737.

Soulsby, WD; Olveda, R; He, J; Berbert, L; Weller, E; Barbour, KE; Greenlund, KJ; Schanberg, LE; Von Scheven, E; Hersh, A; Son, MBF; Chang, J; Knight, A. Racial Disparities and Achievement of the Low Lupus Disease Activity State: A CARRA Registry Study. Arthritis Care and Research. 2025; 77(1):38-49.

Parks, CG; Wilkerson, J; Rose, KM; Faiq, A; Farhadi, PN; Bayat, N; Schiffenbauer, A; Brunner, HI; Goldberg, B; Sandler, DP; Miller, FW; Rider, LG. Occupational and Hobby Exposures Associated With Myositis Phenotypes in a National Myositis Patient Registry. Arthritis Care and Research. 2025; 77(1):104-115.

Maccora, I; Brunner, HI; Cassedy, A; Altaye, M; Quinlan-Waters, M; Lovell, DJ; Grom, A; Angeles-Han, ST. Achieving Medication-Free Remission in Patients With Juvenile Dermatomyositis. ACR Open Rheumatology. 2025; 7(1):e11751.

Randell, RL; Schanberg, LE; Beard, C; Phillips, T; Hornik, CP; Cohen-Wolkowiez, M; Balevic, SJ. Effect of an Electronic Pill Bottle on Hydroxychloroquine Adherence in Pediatric Lupus: Results of a Novel Direct-to-Family Pilot Trial. ACR Open Rheumatology. 2025; 7(1):e11780.

De Lisa, R; De Andres-Trelles, F; Bax, R; Galluzzo, S; Alward, B; Thomson, A; Karres, D; Brunner, HI; Ruperto, N; Egger, GF. New medicines for childhood-onset systemic lupus erythematosus: an EU perspective on paediatric drug development. Frontiers in Medicine. 2025; 12:1583140.

Ogbu, EA; Brunner, HI; Imundo, L. 41 Systemic lupus erythematosus in childhood and adolescence. In: Dubois' Lupus Erythematosus and Related Syndromes. Elsevier; 2025:580-595.

Ogbu, EA; Brunner, HI; Eloseily, E; Aviel, YB; Nanda, K; Schmeling, H; Tory, H; Uziel, Y; Viola, DO; Wahezi, DM; Ruperto, N; Huang, B; Grom, A; Thornton, S. Biomarker Changes in Response to Tofacitinib Treatment in Patients With Polyarticular-Course Juvenile Idiopathic Arthritis. Arthritis Care and Research. 2024; 76(12):1723-1732.

Vega-Fernandez, P; Rogers, K; Avar-Aydin, PO; Quinlan-Waters, M; Huggins, J; Brunner, HI; Lovell, DJ; Altaye, M; Cassedy, A; Meyers, AB; Ting, TV. Validation of the ankle-specific pediatric arthritis ultrasound scoring system in children with juvenile idiopathic arthritis. Seminars in Arthritis and Rheumatism. 2024; 69:152545.

Brunner, HI; Pacheco-Tena, C; Louw, I; Vega-Cornejo, G; Alexeeva, E; Appenzeller, S; Chasnyk, V; Griffin, T; Suarez, CN; Knupp-Oliveira, S; Wang, Y; Lovell, DJ; Martini, A; Ruperto, N. Intravenous Golimumab in Children With Polyarticular-Course Juvenile Idiopathic Arthritis: Long-Term Extension of an Open-Label Phase III Study. Journal of Rheumatology. 2024; 51(11):1125-1134.

Saper, VE; Tian, L; Verstegen, RHJ; Conrad, CK; Cidon, M; Hopper, RK; Kuo, CS; Osoegawa, K; Baszis, K; Bingham, CA; Zemel, LS; Sharma, S; Fernández-Viña, MA; Mellins, ED. Interleukin (IL)-1/IL-6-Inhibitor-Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses. Journal of Allergy and Clinical Immunology: In Practice. 2024; 12(11):2996-3013.e7.

Brunner, HI; Akikusa, JD; Al-Abadi, E; Bohnsack, JF; Boteanu, AL; Chedeville, G; Cuttica, R; De La Pena, W; Jung, L; Kasapcopur, O; Liu, S; Martini, A; Lovell, DJ; Ruperto, N. Safety and efficacy of tofacitinib for the treatment of patients with juvenile idiopathic arthritis: preliminary results of an open-label, long-term extension study. Annals of the Rheumatic Diseases. 2024; 83(11):1561-1571.

Sadun, RE; Cooper, JC; Belot, A; Avcin, T; Aggarwal, A; Ainsworth, J; Akinsete, A; Ardoin, SP; Beresford, MW; Bortey, L; Wenderfer, SE; Woodside, A; Lewandowski, LB; Smith, EM. Development of CARRA/PReS-endorsed consensus Core and Expanded Datasets in childhood-onset systemic lupus erythematosus for international registry-based research. Annals of the Rheumatic Diseases. 2024.

Chang, MH; Barbar-Smiley, F; Akoghlanian, S; Drew, J; Angeles-Han, ST; Quinlan-Waters, M; Bohnsack, JF; Cooper, AM; Edelheit, B; Twachtman-Bassett, J; Lerman, MA; Nanda, K; Rabinovich, CE; Lo, MS. Implementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research. Pediatric Rheumatology. 2024; 22(1):88.

Lovell, DJ; Tzaribachev, N; Henrickson, M; Simonini, G; Griffin, TA; Alexeeva, E; Bohnsack, JF; Zeft, A; Horneff, G; Vehe, RK; Simon, TA; Martini, A; Brunner, HI; Ruperto, N. Safety and effectiveness of abatacept in juvenile idiopathic arthritis: results from the PRINTO/PRCSG registry. Rheumatology. 2024; 63(SI2):SI195-SI206.

Brunner, HI; Ruperto, N; Ramanan, AV; Horneff, G; Minden, K; Calvo Penades, I; Alexeeva, E; Cleary, G; Stern, SM; Kone-Paut, I; Brockwell, L; Gordon, O; Nagel, S; De Benedetti, F. Long-term efficacy and safety of subcutaneous tocilizumab in clinical trials of polyarticular or systemic juvenile idiopathic arthritis. Rheumatology. 2024; 63(9):2535-2546.

Cody, E; Brunner, HI. Renal disease in pediatric rheumatology. Current Opinion in Rheumatology. 2024; 36(5):322-327.

Mannion, ML; Amin, S; Balevic, S; Chang, M-L; Correll, CK; Kearsley-Fleet, L; Hyrich, KL; Beukelman, T. Comparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non-Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular-Course Juvenile Idiopathic Arthritis. Arthritis Care and Research. 2024; 76(8):1090-1098.

Avar-Aydın, PÖ; Brunner, HI. Revisiting Childhood-Onset Systemic Lupus Erythematosus. Turkish Archives of Pediatrics. 2024; 59(4):336-344.

Brunner, HI; Schulert, GS; Sproles, A; Thornton, S; Cornejo, GV; Antón, J; Cuttica, R; Henrickson, M; Foeldvari, I; Kingsbury, DJ; Lovell, DJ; Martini, A; Ruperto, N; Grom, AA. S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis. Arthritis Research & Therapy. 2024; 26(1):125.

Connelly, K; Koelmeyer, R; Ayton, D; May, J; Gregory, K; Eades, L; Barallon, R; Kandane-Rathnayake, R; Golder, V; Anzum, A; Furie, RA; Van Vollenhoven, RF; Banerjee, S; Morand, E. AB0982 DOMAINS FOR INCLUSION IN A NOVEL TREATMENT RESPONSE MEASURE FOR SYSTEMIC LUPUS ERYTHEMATOSUS (TRM-SLE): RESULTS OF A MODIFIED DELPHI STUDY. Annals of the Rheumatic Diseases. 2024; 83:1805-1807.

Peng, J; Dönnes, P; Ardoin, SP; Schanberg, LE; Lewandowski, L; Robinson, G; Jury, EC; Ciurtin, C. Atherosclerosis Progression in the APPLE Trial Can Be Predicted in Young People With Juvenile-Onset Systemic Lupus Erythematosus Using a Novel Lipid Metabolomic Signature. Arthritis & Rheumatology. 2024; 76(3):455-468.

Sinha, R; De Benedetti, F; Grom, AA. Proceedings from the 4th NextGen Therapies for SJIA and MAS virtual symposium held February 13-14, 2022. Pediatric Rheumatology. 2024; 21(Suppl 1):91.

De Benedetti, F; Grom, AA; Brunner, H. The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study. Pediatric Rheumatology. 2024; 21(Suppl 1):150.

Sagcal-Gironella, ACP; Merritt, A; Mizuno, T; Dharnidharka, VR; Mcdonald, J; Deguzman, M; Wahezi, D; Goilav, B; Onel, K; Kim, S; Hersh, A; Huang, B; Devarajan, P; Brunner, H. Efficacy and Safety of Pharmacokinetically-Driven Dosing of Mycophenolate Mofetil for the Treatment of Pediatric Proliferative Lupus Nephritis-A Double-Blind Placebo Controlled Clinical Trial (The Pediatric Lupus Nephritis Mycophenolate Mofetil Study). Journal of Clinical Trials. 2024; 14(4).

Ogbu, EA; Brunner, HI; Imundo, L. Systemic lupus erythematosus in childhood and adolescence. In: Dubois Lupus Erythematosus and Related Syndromes. 2024:580-595.

Huang, B; Kouril, M; Chen, C; Daraiseh, NM; Ferraro, K; Mannion, ML; Brunner, HI; Lovell, DJ; Morgan, EM. Digital health technology to support patient-centered shared decision making at point of care for juvenile idiopathic arthritis. Frontiers in Pediatrics. 2024; 12:1457538.

Brunner, HI; Tzaribachev, N; Louw, I; Calvo Penades, I; Avila-Zapata, F; Horneff, G; Foeldvari, I; Kingsbury, DJ; Paz Gastanaga, ME; Wouters, C; Zhuo, J; Martini, A; Lovell, DJ; Ruperto, N. Long-Term Maintenance of Clinical Responses by Individual Patients With Polyarticular-Course Juvenile Idiopathic Arthritis Treated With Abatacept. Arthritis Care and Research. 2023; 75(11):2259-2266.

Woo, JMP; Simmonds, F; Dennos, A; Son, MBF; Lewandowski, LB; Rubinstein, TB. Health Equity Implications of Missing Data Among Youths With Childhood-Onset Systemic Lupus Erythematosus: A Proof-of-Concept Study in the Childhood Arthritis and Rheumatology Research Alliance Registry. Arthritis Care and Research. 2023; 75(11):2285-2294.

Ruperto, N; Lovell, DJ; Berman, A; Anton, J; Viola, DO; Lauwerys, B; Rama, ME; Bohnsack, J; Breedt, J; Fischbach, M; Wong, R; Askelson, M; Martini, A; Brunner, HI. Abatacept as Monotherapy and in Combination With Methotrexate in Patients With Juvenile Idiopathic Arthritis: Analysis of 2 Phase III Trials. Journal of Rheumatology. 2023; 50(11):1471-1480.

Brucia, RC; Hayward, K; Brunner, HI; Lopez-Pena, M; Shenoi, S; Soybilgic, A; Nocton, JJ. Practice Analysis and Determining the Knowledge and Skills Expected of a Pediatric Rheumatologist. ACR Open Rheumatology. 2023; 5(11):619-623.

Schanberg, LE; Mulugeta, LY; Akinlade, B; Brunner, HI; Chen, J; Colbert, RA; Delgaizo, V; Gastonguay, MR; Glaser, R; Imundo, L; Singh, R; Sinha, V; Yancey, CL; Yao, L. Therapeutic Development in Polyarticular Course Juvenile Idiopathic Arthritis: Extrapolation, Dose Selection, and Clinical Trial Design. Arthritis & Rheumatology. 2023; 75(10):1856-1866.

Connelly, K; Eades, LE; Koelmeyer, R; Ayton, D; Golder, V; Kandane-Rathnayake, R; Gregory, K; Brunner, H; Burke, L; Arnaud, L; Zuraw, Q; Werth, V; Garces, S; Morand, EF. Towards a novel clinical outcome assessment for systemic lupus erythematosus: first outcomes of an international taskforce. Nature reviews. Rheumatology. 2023; 19(9):592-602.

Ramanan, AV; Quartier, P; Okamoto, N; Foeldvari, I; Spindler, A; Fingerhutová, Š; Antón, J; Wang, Z; Meszaros, G; Araújo, J; Liao, R; Keller, S; Brunner, HI; Ruperto, N. Baricitinib in juvenile idiopathic arthritis: an international, phase 3, randomised, double-blind, placebo-controlled, withdrawal, efficacy, and safety trial. The Lancet. 2023; 402(10401):555-570.

Ruperto, N; Lovell, DJ; Berman, A; Ávila-Zapata, F; Horneff, G; Alessio, M; Becker, ML; Belot, A; Burgos-Vargas, R; Gamir, ML; Askelson, M; Wong, R; Martini, A; Brunner, HI. Patient-Reported Outcomes Among Patients Ages Two to Seventeen Years With Polyarticular-Course Juvenile Idiopathic Arthritis Treated With Subcutaneous Abatacept: Two-Year Results From an International Phase III Study. Arthritis Care and Research. 2023; 75(8):1804-1814.

Cody, EM; Wenderfer, SE; Sullivan, KE; Kim, AHJ; Figg, W; Ghumman, H; Qiu, T; Huang, B; Devarajan, P; Brunner, HI. Urine biomarker score captures response to induction therapy with lupus nephritis. Pediatric Nephrology. 2023; 38(8):2679-2688.

Roberts, JE; Williams, K; Dallas, J; Eckert, M; Huie, L; Smitherman, E; Soulsby, WD; Zhao, Y; Son, MBF. Insurance Status and Tumor Necrosis Factor Inhibitor Initiation Among Children With Juvenile Idiopathic Arthritis in the CARRA Registry. Journal of Rheumatology. 2023; 50(8):1047-1057.

Smitherman, EA; Chahine, RA; Beukelman, T; Lewandowski, LB; Rahman, AKMF; Wenderfer, SE; Curtis, JR; Hersh, AO. Childhood-Onset Lupus Nephritis in the Childhood Arthritis and Rheumatology Research Alliance Registry: Short-Term Kidney Status and Variation in Care. Arthritis Care and Research. 2023; 75(7):1553-1562.

Brunner, HI; Vadhariya, A; Dickson, C; Crandall, W; Kar-Chan Choong, C; Birt, JA; Ruperto, N; Ramanan, AV. Treatment patterns in paediatric and adult patients with SLE: a retrospective claims database study in the USA. Lupus Science and Medicine. 2023; 10(2).

Ruperto, N; Foeldvari, I; Alexeeva, E; Ayaz, NA; Schulert, G; Özen, S; Popov, A; Ramanan, A; Scott, C; Sozeri, B; Pricop, L; Lovell, DJ; Martini, A; Brunner, H. POS0278 EFFICACY AND SAFETY OF SECUKINUMAB IN JUVENILE IDIOPATHIC ARTHRITIS: INTERIM RESULTS FROM THE EXTENSION OF THE JUNIPERA TRIAL. Annals of the Rheumatic Diseases. 2023; 82:379-380.

Hawtin, S; André, C; Zipfel, GC; Appenzeller, S; Bannert, B; Baumgartner, L; Beck, D; Betschart, C; Boulay, T; Brunner, H; Siegel, R; Gergely, P; Shisha, T; Junt, T. POS1140 A NOVEL TLR7/8 ANTAGONIST BLOCKS PRO-INFLAMMATORY FUNCTION OF IMMUNE COMPLEXES FROM LUPUS PATIENTS AND ABROGATES LUPUS-LIKE DISEASE IN MICE. Annals of the Rheumatic Diseases. 2023; 82:899.

Hawtin, S; André, C; Collignon-Zipfel, G; Appenzeller, S; Bannert, B; Baumgartner, L; Beck, D; Betschart, C; Boulay, T; Brunner, HI; Siegel, R; Gergely, P; Shisha, T; Junt, T. Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy. Cell Reports Medicine. 2023; 4(5):101036.

Johnson, SR; Gladman, DD; Brunner, HI; Isenberg, D; Clarke, AE; Barber, MRW; Arnaud, L; Fortin, PR; Mosca, M; Voskuyl, AE; Waldhauser, H; Wallace, DJ; Zoma, A; Bruce, IN. Evaluating the Construct of Damage in Systemic Lupus Erythematosus. Arthritis Care and Research. 2023; 75(5):998-1006.

Stotter, BR; Cody, E; Gu, H; Daga, A; Greenbaum, LA; Duong, MD; Mazo, A; Goilav, B; Boneparth, A; Kallash, M; Levy, DM; Brunner, HI; Verghese, PS; Wenderfer, SE. Acute kidney injury requiring kidney replacement therapy in childhood lupus nephritis: a cohort study of the Pediatric Nephrology Research Consortium and Childhood Arthritis and Rheumatology Research Alliance. Pediatric Nephrology. 2023; 38(5):1653-1665.

Cody, EM; Wilson, BE; Ogbu, EA; Huggins, JL; Chen, C; Qiu, T; Ting, TV; Flores, F; Huang, B; Brunner, HI. Usefulness of the lupus low disease activity state as a treatment target in childhood-onset SLE. Lupus Science and Medicine. 2023; 10(1).

Ringold, S; Dennos, AC; Kimura, Y; Beukelman, T; Shrader, P; Phillips, TA; Kohlheim, M; Schanberg, LE; Yeung, RSM; Horton, DB. Disease Recapture Rates After Medication Discontinuation and Flare in Juvenile Idiopathic Arthritis: An Observational Study Within the Childhood Arthritis and Rheumatology Research Alliance Registry. Arthritis Care and Research. 2023; 75(4):715-723.

Shiff, NJ; Shrader, P; Correll, CK; Dennos, A; Phillips, T; Beukelman, T. Trajectories of disease activity in patients with JIA in the Childhood Arthritis and Rheumatology Research Alliance Registry. Rheumatology. 2023; 62(2):804-814.

Brunner, HI; Foeldvari, I; Alexeeva, E; Ayaz, NA; Calvo Penades, I; Kasapcopur, O; Chasnyk, VG; Hufnagel, M; Żuber, Z; Schulert, G; Pricop, L; Martini, A; Lovell, D; Ruperto, N. Secukinumab in enthesitis-related arthritis and juvenile psoriatic arthritis: a randomised, double-blind, placebo-controlled, treatment withdrawal, phase 3 trial. Annals of the Rheumatic Diseases. 2023; 82(1):154-160.

Smitherman, EA; Chahine, RA; Bitencourt, N; Rahman, AKMF; Lawson, EF; Chang, JC. Patient-Reported Outcomes Among Transition-Age Young Adults With Juvenile Idiopathic Arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry. Journal of Rheumatology. 2023; 50(1):98-106.

Borgia, RE; Gurka, MJ; Filipp, SL; Elder, M; Cardel, M; Shiff, NJ. Race, ethnicity and patient-reported outcomes in childhood-onset systemic lupus erythematosus. Clinical and Experimental Rheumatology. 2023; 41(1):186-194.

Petri, M; Aringer, M; Ayoub, I; Almaani, S; Brunner, H; Dall’Era, M; Jiang, M; Furie, R; Greco, J; Goldblatt, F; Rovin, B; Wallace, D; Zhang, X; Zhao, L. Systemic Lupus Erythematosus. In: A Clinician's Pearls & Myths in Rheumatology. Springer Nature; 2023:167-212.

Miraldi Utz, V; Angeles-Han, ST; Mwase, N; Cassedy, A; Hennard, T; Lovell, DJ; Lopper, S; Brunner, HI; Dosunmu, EO; Grom, AA; Henrickson, M; Huggins, JL; Sisk, RA; Ting, TV; Kaufman, AH. Alternative Biologic Therapy in Children Failing Conventional TNFα Inhibitors for Refractory, Noninfectious, Chronic Anterior Uveitis. American Journal of Ophthalmology. 2022; 244:183-195.

Hahn, T; Daymont, C; Beukelman, T; Groh, B; Hays, K; Bingham, CA; Scalzi, L. Intraarticular steroids as DMARD-sparing agents for juvenile idiopathic arthritis flares: Analysis of the Childhood Arthritis and Rheumatology Research Alliance Registry. Pediatric Rheumatology. 2022; 20(1):107.

Cody, E; Rose, J; Hopkins, R; Quinlan-Waters, M; Robben, CE; Qiu, T; Huang, B; Devarajan, P; Brunner, H. Stability of Novel Urinary Biomarkers Used for Lupus Nephritis. Journal of the American Society of Nephrology. 2022; 33(11S):961-962.

Ogbu, EA; Brunner, HI. Treatment Guidelines in Pediatric Rheumatic Diseases. Rheumatic Disease Clinics of North America. 2022; 48(3):725-746.

Neely, J; Ardalan, K; Huber, A; Kim, S. Baseline characteristics of children with juvenile dermatomyositis enrolled in the first year of the new Childhood Arthritis and Rheumatology Research Alliance registry. Pediatric Rheumatology. 2022; 20(1):50.

Weiss, PF; Fuhlbrigge, RC; Von Scheven, E; Lovell, DJ; Colbert, RA; Brunner, HI. Children With Enthesitis-Related Arthritis and Possible Benefits From Treatments for Adults With Spondyloarthritis. Arthritis Care and Research. 2022; 74(7):1058-1064.

Gerss, J; Tedy, M; Klein, A; Horneff, G; Miranda-Garcia, M; Kessel, C; Holzinger, D; Stanevica, V; Swart, JF; Cabral, DA; Brunner, HI; Foell, D. Prevention of disease flares by risk-adapted stratification of therapy withdrawal in juvenile idiopathic arthritis: results from the PREVENT-JIA trial. Annals of the Rheumatic Diseases. 2022; 81(7):990-997.

Ruperto, N; Brunner, H; Berman, A; Zapata, FA; Horneff, G; Wagner-Weiner, L; Belot, A; Burgos-Vargas, R; Gámir, MLG; Goldenstein-Schainberg, C; Wong, R; Martini, A; Lovell, DJ; Group, PRITOATPRCS. POS0340 PREDICTORS OF CLINICAL RESPONSE TO ABATACEPT IN CHILDREN WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS. Annals of the Rheumatic Diseases. 2022; 81:422-423.

Ruperto, N; Chertok, E; Dehoorne, J; Horneff, G; Kallinich, T; Louw, I; Compeyrot-Lacassagne, S; Lauwerys, B; Martin, N; Marzan, K; Martini, A; Lovell, DJ; Brunner, H; Group, PRITOAPRCS. OP0221 EFFICACY OF SECUKINUMAB IN ENTHESITIS-RELATED ARTHRITIS: RESULTS FROM A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, TREATMENT WITHDRAWAL, PHASE 3 STUDY (JUNIPERA) Annals of the Rheumatic Diseases. 2022; 81:145-146.

Ramanan, A; Quartier, P; Okamoto, N; Meszaros, G; Araujo, J; Wang, Z; Liao, R; Crowe, B; Zhang, X; Decker, R; Keller, S; Brunner, H; Ruperto, N. LB0002 BARICITINIB IN JUVENILE IDIOPATHIC ARTHRITIS: A PHASE 3, DOUBLE-BLIND, PLACEBO-CONTROLLED, WITHDRAWAL, EFFICACY AND SAFETY STUDY. Annals of the Rheumatic Diseases. 2022; 81:207-208.

Ruperto, N; Brunner, HI; Posner, HB; Lazariciu, I; Martini, A; Lovell, DJ. Tofacitinib for juvenile idiopathic arthritis - Authors' reply. The Lancet. 2022; 399(10338):1866.

Aljaberi, N; Wenderfer, SE; Mathur, A; Qiu, T; Jose, S; Merritt, A; Rose, J; Devarajan, P; Huang, B; Brunner, H. Clinical measurement of lupus nephritis activity is inferior to biomarker-based activity assessment using the renal activity index for lupus nephritis in childhood-onset systemic lupus erythematosus. Lupus Science and Medicine. 2022; 9(1).

Soulsby, WD; Balmuri, N; Cooley, V; Gerber, LM; Lawson, E; Goodman, S; Onel, K; Mehta, B. Social determinants of health influence disease activity and functional disability in Polyarticular Juvenile Idiopathic Arthritis. Pediatric Rheumatology. 2022; 20(1):18.

Chalhoub, NE; Wenderfer, SE; Levy, DM; Rouster-Stevens, K; Aggarwal, A; Savani, SI; Ruth, NM; Arkachaisri, T; Qiu, T; Merritt, A; Al-Mayouf, SM; Devarajan, P; Huang, B; Brunner, HI. International Consensus for the Dosing of Corticosteroids in Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis. Arthritis & Rheumatology. 2022; 74(2):263-273.

Cody, EM; Brunner, HI. Biomarkers in Childhood-Onset Systemic Lupus Erythematosus. Rheumatic Disease Clinics of North America. 2022; 48(1):271-285.

Martini, A; Lovell, DJ; Albani, S; Brunner, HI; Hyrich, KL; Thompson, SD; Ruperto, N. Juvenile idiopathic arthritis. Springer Nature; 2022:5.

Andrade Balbi, V; Artur Silva, C; Nascimento Pedrosa, T; Maria Rodrigues Pereira, R; Maria De Arruda Campos, L; Pires Leon, E; Duarte, N; Melechco Carvalho, V; Gofinet Pasoto, S; Cordeiro Do Rosário, D; Kolachinski Brandao, L; I Brunner, H; Bonfá, E; Emi Aikawa, N. Hydroxychloroquine blood levels predicts flare in childhood-onset lupus nephritis. Lupus. 2022; 31(1):97-104.

Hossain, MM; Wilkerson, J; Mcgrath, JA; Farhadi, PN; Brokamp, C; Khan, MTF; Goldberg, B; Brunner, HI; Macaluso, M; Miller, FW; Rider, LG. The Geospatial Distribution of Myositis and Its Phenotypes in the United States and Associations With Roadways: Findings From a National Myositis Patient Registry. Frontiers in Medicine. 2022; 9:842586.

Cody, EM; Rose, JE; Huang, B; Qiu, T; Brunner, HI; Devarajan, P. Stability of novel urinary biomarkers used for lupus nephritis. Frontiers in Pediatrics. 2022; 10:974049.

De Amorim, JC; Kishimoto, ST; Elorza, CLC; Cavaletti, FA; Marini, R; Silva, CA; Saad-Magalhães, C; Fernandes, PT; Brunner, HI; Appenzeller, S. Cross-cultural adaptation and initial validation of the Brazilian-Portuguese version of the pediatric automated neuropsychological assessment metrics. Frontiers in Psychology. 2022; 13:945425.