Clinical Trials

ARST1321: Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613)

• Conditions: Brain Spinal Neurofibromatosis Sarcoma MPNST New Diagnosis, Solid Tumor Neurofibromatosis Sarcoma MPNST New Diagnosis, Adult - Brain Spinal Neurofibromatosis Sarcoma MPNST New Diagnosis, Adult - Solid Tumor Neurofibromatosis Sarcoma MPNST New Diagnosis

This randomized phase II/III trial studies how well pazopanib hydrochloride, combination chemotherapy, and radiation therapy work and compares it to radiation therapy alone or in combination with pazopanib hydrochloride or combination chemotherapy in treating patients with newly diagnosed non-rhabdo ...More