3 to 12 Month Olds with Tuberous Sclerosis Complex (TSC) Needed for Research Study

  • Conditions: Autism - Fragile X, Neurology, Tuberous Sclerosis

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to look for early signs of autism in children with Tuberous Sclerosis Complex (TSC), a genetic disorder where autism is common. ...More

6 to 18 Year Olds with Chronic Migraine Needed for a Research Study

  • Conditions: Neurology, Headaches - Migraines

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to look at what is happening in the brain, using a machine called an MEG, before and after someone has started treatment for a migraine.    A MEG measures the ma ...More

ACNS0821: Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial

  • Conditions: Cancer - Brain and Spinal Tumors, Neurology
  • Gender: Female, Male

This randomized phase II trial is studying how well giving temozolomide and irinotecan hydrochloride together with or without bevacizumab works in treating young patients with recurrent or refractory medulloblastoma or CNS primitive neuroectodermal tumors. ...More

Adults, 18 to 64 Year Olds, with Tourette Syndrome Needed for a Research Study

  • Conditions: Neurology

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn more about the safety, tolerability and effectiveness of an investigational drug for the treatment of Tourette syndrome (TS). We also want to see how the body absorbs, processe ...More

ADVL0815: Phase I Study Pazopanib Single Agent for Solid Tumor

  • Conditions: Cancer - Brain and Spinal Tumors, Cancer - Liver Tumors, Neurology
  • Gender: Female, Male

This phase I trial is studying the side effects and best dose of pazopanib hydrochloride in treating young patients with solid tumors that have relapsed or not responded to treatment. ...More

Children and Teens, 6 to 16 Year Olds, with Tourette Syndrome Needed for a Research Study

  • Conditions: Neurology

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn more about the safety, tolerability and effectiveness of an investigational drug for the treatment of Tourette syndrome (TS). We also want to see how the body absorbs, processe ...More

Has Your Child or Teen Had a Moderate to Severe Head Injury? Do They Have Trouble with Concentration or Staying Focused?

  • Conditions: Neurology, Brain - Spinal Cord - Nerves, Concussion - Head Injury

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn more about how a medication that helps with attention problems can help children who have had a moderate to severe head injury. This research study is called Focus On Concerta® ...More

Research Study for Healthy Children and Adults 8 to 60 Years Old

  • Conditions: Adult Studies, Healthy Adults, Healthy Babies Children and Teens, Neurology

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to compare the electrical patterns of the brain in healthy children and adults to those of child and adult patients with Tourette’s syndrome.   ...More

Research Study for Infants, Children and Teens with a Congenital Structural Brain Disorder

  • Conditions: Hydrocephalus, Genetics - Chromosome Abnormalities, Neurology, Spina Bifida, Brain - Spinal Cord - Nerves

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn more about congenital conditions affecting the structure and function of the developing brain. We also want to find the genetic causes for people with congenital structural bra ...More

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Adult Participants or Parents of Participants:

Cincinnati Children’s is involved in research because it is very important to understanding diseases and developing ways to prevent and treat health problems in children, as well as adults. Learn more about how you can help. Contact us at clinicalstudies@cchmc.org or 513-636-0098. Or, enroll in our database to be notified about future studies by completing an online sign up form.

Sponsors and Investigators:

The Office for Clinical and Translational Research at Cincinnati Children’s provides sponsors and investigators with comprehensive support services, research tools, personnel and facilities to conduct or facilitate pediatric and adult clinical research studies. Contact us at OCTR@cchmc.org or 513-636-0314.