Clinical Trials / Research Studies
Clinical Trials / Research Studies

Study for Healthy Children 4 and 5 Years Old

Why are we doing this research?

Cincinnati Children's is conducting a research study to better understand why some children have difficulties making speech sounds. This study will look at how brain function may differ in children with and without speech problems.

Who can participate?

Healthy children 4 and 5 years may be eligible to participate.


  • Healthy Infants, Children and Adolescent Studies

What will happen in the study?

This study includes 1 or more study visits at Cincinnati Children’s that will take about 7 to 8 hours. You may complete all of the procedures in the study in 1 day, or you may come back on different days within 4 weeks.

Here are some of the things that will happen in this study:

Your child will have:

  • Speech and language screening tests to see if he/she qualifies for the study.
  • A hearing test, if one has not been completed recently.
  • A brain MRI that will last about 1 hr. Your child will listen to sounds or words and/or complete simple speaking tasks while in the scanner. For some of the time in the scanner, he/she will be able to watch a movie of their choice.
  • A brain MEG, a scan that identifies brain activity, which will last about 1 hr. Your child will be able to view pictures or video using a mirror and will listen to sounds using earphones.
  • Additional speech, language and other tests after the scans which will take 2 to 3 hrs.

You will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

Your child may not have a direct medical benefit for taking part in this research study. However, possible benefits include learning more about your child’s speech, language and thinking skills. In the future, we hope to use the information from this study to develop better speech therapy for children with speech problems.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed with parents or guardians interested in learning more about the study.

Will you/your child be paid to be in this research study?

Families may receive up to $120 for time and effort.


Contact Us.Julie Plummer
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Jennifer Vannest, PhD
Cincinnati Children’s Hospital Medical Center