Clinical Trials / Research Studies
Clinical Trials / Research Studies

Identification of Biomarkers for Patients with Vascular Anomalies

Why are we doing this research?

While vascular anomalies are rare diseases, they can be life-threatening and devastating to affected patients and their families. Our understanding of vascular anomalies, and in turn their treatments, can be greatly improved if non-invasive biomarkers can be identified. The goal of this research study is to identify these biomarkers to aid in diagnosis and for better treatment options to be developed.

Who can participate?

Any patient who has been diagnosed with a vascular anomaly is eligible for participation in this study.


  • Hematology - Hemangioma and Vascular Malformation

What will happen in the study?

This study makes use of specimens obtained via many different means. These include:

  1. Blood and tissue specimens obtained from patients who have been consented previously to an internal tissue repository study maintained by the Department of Hematology and Oncology at Cincinnati Children’s Hospital Medical Center.
  2. Specimens from tissue repositories both internal and external to CCHMC.
  3. Tissue or fluid samples that may be collected in the future from patients undergoing surgical removal of the vascular anomalies that are relevant to this study.

These specimens will only be obtained if/when you/your child are having these procedures performed as part of you/your child’s clinical care. There will be no additional blood draws, surgical procedures, or visits associated with this study.

Once obtained, these specimens will be analyzed for the presence of biomarkers with correlation to the vascular diagnosis.

What are the good things that can happen from this research?

While there are no direct benefits to you/your child for participating in this study identification of these biomarkers could provide a safer way to diagnose and treat different vascular anomalies, both for current and future patients.

What are the bad things that can happen from this research?

The only risks for participation in this study lie in the clinical procedures themselves, and the storage of you/your child’s private health information in databases.

You/your child may feel discomfort when getting blood drawn or when undergoing a surgery.

Additionally, basic clinical and demographic information from you/your child’s medical chart will be collected and stored in an internal database at CCHMC. There is a possibility that some of you/your child’s private health information could be compromised. To prevent this, all information entered or collected from the database will be de-identified.

Will you/your child be paid to be in this research study?

You/your child will not receive payment for participating in this study.


Contact Us.

Study Personnel Contact Information
Phone Number: 513-803-4862