Heart Failure and Transplant Program

Clinical

Neonatal and congenital heart surgery and pediatric heart transplantation with specialty certification in Berlin Heart Surgical implantation and training.

Research

Ex vivo analysis of the pediatric donor heart and pediatric mechanical circulatory support.

BA: Biology, Dillard University, New Orleans, LA, 1990.

MS: Boston University, Boston, BA, 1999.

MD: Boston University, School of Medicine, Boston, MA.

Internship and Residency: General Surgery, University of Kansas, Kansas City, KS, 2004.

Residency: Cardiovascular and Thoracic Surgery, Cleveland Clinic, Cleveland, OH, 2007.

Fellowship: Congenital Heart Surgery, Texas Children's Hospital, Houston, TX, 2009.

Arain N, Braunlin E, St. Louis J, Bryant R 3rd. Delayed Arterial Switch Operation in a Patient with Complete Transposition of the Great Arteries and Glucocorticoid Remediable Aldosteronism. World Journal for Pediatric and Congenital Heart Surgery. 2011 Apr; 2(2):316-17.

Bryant R 3rd, Steiner M, St. Louis JD. Current Use of the EXCOR Pediatric Ventricular Assist Device. J Cardiovasc Transl Res. 2010 Dec;3(6):612-7.

Shepard CW, Kochilas LK, Rosengart RM, Bryant R 3rd, Moller JH, St. Louis JD. Repair of Major Cardiac Defects in Low Birth Weight Infants; Is Delay Warranted? J Thorac Cardiovasc Surg. 2010 Nov;140(5):1104-9.

Arain N, Bryant R 3rd, Ameduri R, Gruenstein D, Braunlin E, Joyce L, St. Louis J. Successful Coil Embolization of a Large Ascending Aortic Pseudoaneurysm Following Explanation of the EXCOR Pediatric Ventricular Assist Device in a Patient with Acute Fulminant Myocarditis. World Journal for Pediatric and Congenital Heart Surgery. 2010;1(2): 259-26.

Owens WR, Bryant R 3rd,Dreyer WJ, Price JF, Morales D. Initial Experience with the Heart Mate II Ventricular Assist System in a Pediatric Institution. Artif Organs. 2010 Jul;34(7):600-3.

Booth JH, Bryant R 3rd, Powers SC, Ge S, McKenzie ED, Heinle JS, Fraser CD, Morales D. Transthoracic Echocardiography Does Not Reliably Predict Involvement of the Aortic Valve in Patients with Discrete Subaortic Shelf. Cardiol Young. 2010 Jun;20(3):284-9.

Zhi D, Bryant R 3rd, Heinle J, Nihill M. Isolated Cleft of the Mitral Valve: Clinical Spectrum and Course. Tex Heart Inst J. 2009;36(6):553-6.

Bryant R 3^rd, Morales D. Corkscrew Trachea: A Novel Type of Distal Congenital Tracheal Stenosis. Ann Thorac Surg. 2009 Jun;87(6):1923-5.

Booth JH, Bryant R 3rd, Vaporciyan A, Morales D. Complete Lung Parenchyma Sparing Resection of the Right Main Stem Bronchus and Bronchus Intermedius. J Thorac Cardiovasc Surg. 2009 Mar 6.

Bryant R 3rd, Phalak K, Morales D. Multimodality Therapy for Primary Sternal Osteomyelitis. Pediatr Infect Dis J. 2009 Jan;28(1):73-4.

Clifford Chin, MD Co-Director, Advanced Heart Failure and Cardiomyopathy 513-803-3151 clifford.chin@cchmc.org

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Clifford Chin, MD

Co-Director, Advanced Heart Failure and Cardiomyopathy

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-803-3151

Fax 513-803-7869

Email clifford.chin@cchmc.org

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Clinical

Pediatric cardiology; cardiomyopathy and transplantation

Research

Cardiomyopathy and transplantation

MD: SUNY Downstate Medical Center, Brooklyn, NY, 1989.

Residency: Pediatrics, University of California Davis Medical Center, Sacramento, CA, 1989.

Fellowship: Stanford University, Stanford, CA, 1992.

Castleberry C, Ryan T, Chin C. Transplantation in the Highly Sensitized Pediatric Patient. Circulation. 2014;129:2313-2319.

Chin C. Pediatric Antibody Mediated Rejection. Pediatric Transplantation. 2012;16:404-4012.

Pietra B, Kantor P, Bartlett H, Chin C, Canter C, Larsen R, Edens E, Colan C, Towbin T, Lipshultz S, Kirklin J, Naftel D, Sleeper L, Hsu D. Early Predictors of Survival to and After Clinical Heart Transplantation in Children’ with Dilated Cardiomyopathy. Circulation. 2012;126:1079-86.

Chin C, Chen G, Sequeria F, Berry G, Siehr S, Bernstein D, Rosenthal D, Reinhartz O, Tyan D. Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. J Heart Lung Transplant. 2011 Feb;30(2):158-63.

Chin C, Lukito SS, Shek J, Bernstein D, Perry SB. Prevention of pediatric graft coronary artery disease: atorvastatin. Pediatr Transplant. 2008 Jun;12(4):442-6.

Potena L, Fearon WF, Sydow K, Holweg C, Luikart H, Chin C, Weisshaar D, Mocarski ES, Lewis DB, Valantine HA, Cooke JP. Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation. 2008 Mar 27;85(6):827-33.

Tu W, Potena L, Stepick-Biek P, Liu L, Dionis KY, Luikart H, Fearon WF, Holmes TH, Chin C, Cooke JP, Valantine HA, Mocarski ES, Lewis DB. T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. Circulation. 2006 Oct 10;114(15):1608-15.

Potena L, Holweg CT, Chin C, Luikart H, Weisshaar D, Narasimhan B, Fearon WF, Lewis DB, Cooke JP, Mocarski ES, Valantine HA. Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation. 2006 Aug 15;82(3):398-405.

Chin C, Naftel D, Pahl E, Shankel T, Clark ML, Gamberg P, Kirklin J, Webber S; Pediatric Heart Transplant Study. Cardiac re-transplantation in pediatrics: a multi-institutional study. J Heart Lung Transplant. 2006 Dec;25(12):1420-4.

Chin C, Naftel DC, Singh TP, Blume ED, Luikart H, Bernstein D, Gamberg P, Kirklin JK, Morrow WR, Pediatric Heart Transplant Study Group. Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience. J Heart Lung Transplant. 2004 Feb;23(2):178-85.

Grants

Biomarkers for post-transplant lymphoproliferative disorder in children. Site investigator. National Institute of Allergy and Infectious Diseases. 2015 - present.

Lisa M. Dodd, MSSW, LISW Social Worker, Heart Institute 513-636-0328 lisa.dodd@cchmc.org

John L. Jefferies, MD, MPH, FAAP, FACC Co-Director, Advanced Heart Failure and Cardiomyopathy 513-803-1675 john.jefferies@cchmc.org

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John L. Jefferies, MD, MPH, FAAP, FACC

Co-Director, Advanced Heart Failure and Cardiomyopathy

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-803-1675

Email john.jefferies@cchmc.org

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Clinical

Advanced heart failure; cardiomyopathy; mechanical circulatory support and transplant

Research

Heritable causes of vascular disease; novel drug therapies for advanced heart failure; novel gene discovery in cardiomyopathy; characterization and management of left ventricular noncompaction (LVNC); early diagnosis and management of chemotherapy induced cardiotoxicity.

Biography

Dr. Jefferies, a professor of pediatric cardiology and adult cardiovascular diseases within the University of Cincinnati College of Medicine, is the director of Advanced Heart Failure / Cardiomyopathy in the Heart Institute at Cincinnati Children's Hospital Medical Center.

He completed his combined pediatric and adult cardiology training at the Baylor College of Medicine in Houston, Texas at the Texas Children's Hospital and the Texas Heart Institute. He has authored or co-authored over 120 peer-reviewed manuscripts and book chapters on cardiomyopathy, cardiovascular genetics, and adults with congenital heart disease.

His current research interests include heritable causes of cardiovascular disease, novel drug therapies for advanced heart failure, novel gene discovery in cardiomyopathy, characterization and management of left ventricular noncompaction (LVNC), and early diagnosis and management of chemotherapy induced cardiotoxicity.

He is on the editorial board of the Texas Heart Institute Journal and is an active member of numerous professional organizations, including the Heart Failure Society of America, the American College of Cardiology and the American Heart Association. He is the lead editor for two textbooks that focus on the management of heart disease in children and young adults entitled “Heart Failure in the Child and Young Adult: From Bench to Bedside” and “Cardioskeletal Myopathies in Children and Young Adults.”

BS: University of Tennessee, Knoxville, TN, 1992.

MD: University of Tennessee, Knoxville, TN, 1996.

Residency: University of Kentucky, Lexington, KY, 2000.

MPH: University of Kentucky, Lexington, KY, 2001.

Fellowship: Baylor College of Medicine, Houston, TX, 2006.

Certification: Pediatrics, Internal Medicine, Cardiology, Advanced Heart Failure, Cardiac Transplant.

Towbin JA, Lorts A, Jefferies JL. Left ventricular noncompaction cardiomyopathy. Lancet. 2015;Apr 9. Epub ahead of print.

McCullough PA, Jefferies JL. Novel Markers And Therapies For Patients With Acute Heart Failure And Renal Dysfunction. Am J Med. 2015 Mar;128(3):312.e1-22.

Villa CR, Ryan TD, Collins JJ, Taylor MD, Lucky AW, Jefferies JL. Left ventricular non-compaction cardiomyopathy associated with epidermolysis bullosa simplex with muscular dystrophy and PLEC1 mutation. Neuromuscul Disord. 2015 Feb;25(2):165-8.

Raman SV, Hor KN, Halnon NJ, Kissel JT, He X, Tran T, Smart S, McCarthy B, Taylor MD, Jefferies JL, Rafael-Fortney JA, Lowe J, Roble SL, Cripe LH. Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2015 Feb;14(2):153-61.

Jefferies JL. Barth syndrome. Am J Med Genet C Semin Med Genet. 2013 Aug;163C(3):198-205.

Breinholt JP, Moulik M, Dreyer WJ, Denfield SW, Kim JJ, Jefferies JL, Rossano JW, Gates CM, Clunie SK, Bowles KR, Kearney DL, Bowles NE, Towbin JA. Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients. J Heart Lung Transplant. 2010 Jul;29(7):739-46.

Carlson P, Jefferies JL, Kearney D, Russell H. Refractory dilated cardiomyopathy associated with metastatic neuroblastoma. Pediatr Blood Cancer. 2010 Jun 29.

Shah AM, Jefferies JL, Rossano JW, Decker JA, Cannon BC, Kim JJ. Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm. 2010 Jun 18.

Rossano JW, Morales DL, Zafar F, Denfield SW, Kim JJ, Jefferies JL, Dreyer WJ. Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: An analysis of the United Network for Organ Sharing database. J Thorac Cardiovasc Surg. 2010 May 26.

Jefferies JL, Towbin JA. Dilated cardiomyopathy. Lancet. 2010 Feb;375(9716):752-62.

Angela Lorts, MD Director, Ventricular Assist Device Program 513-803-4580 angela.lorts@cchmc.org

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Angela Lorts, MD

Director, Ventricular Assist Device Program

Academic Affiliations

Associate Professor, UC Department of Pediatrics

Phone 513-803-4580

Fax 513-636-3952

Email angela.lorts@cchmc.org

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Clinical

Advanced heart failure; cardiopulmonary bypass mediated myocardial dysfunction; novel uses of pediatric VADs; cardiomyopathy; mechanical circulatory support and transplant

Research

Myocardial remodeling

MD: Creighton University Medical School, Omaha, NE, 1998.

Residency: The Children’s Hospital, Denver, CO, 2001.

Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2004; University of Michigan Medical Center, Ann Arbor, MI, 2006.

Certifications: American Board of Pediatrics, 2001; American Board of Pediatrics, Sub-Board of Pediatric Cardiology, 2004; American Board of Pediatrics, Sub-Board of Pediatric Critical Care, 2006.

Towbin JA, Lorts A, Jefferies JL. Left ventricular non-compaction cardiomyopathy. Lancet. 2015 Apr 9.

Benoit S, Antommaria AH, Weidner N, Lorts A. Difficult decision: what should we do when a VAD-supported child experiences a severe stroke? Pediatr Transplant. 2015 Mar;19(2):139-43.

Zafar F, Castleberry C, Khan MS, Mehta V, Bryant R 3rd, Lorts A, Wilmot I, Jefferies JL, Chin C, Morales DL. Pediatric heart transplant waiting list mortality in the era of ventricular assist devices. J Heart Lung Transplant. 2015 Jan;34(1):82-8.

Thomas TO, Chandrakasan S, O'Brien M, Jefferies JL, Ryan TD, Wilmot I, Baker ML, Madueme PC, Morales D, Lorts A. The use of a Berlin Heart EXCOR LVAD in a child receiving chemotherapy for Castleman's disease. Pediatr Transplant. 2015 Feb;19(1):E15-8.

Thomas TO, Jefferies JL, Lorts A, Anderson JB, Gao Z, Benson DW, Hor KN, Cripe LH, Urbina EM. Autonomic dysfunction: a driving force for myocardial fibrosis in young Duchenne muscular dystrophy patients? Pediatr Cardiol. 2015 Mar;36(3):561-8.

Friess MR, Marino BS, Cassedy A, Wilmot I, Jefferies JL, Lorts A. Health-related quality of life assessment in children followed in a cardiomyopathy clinic. Pediatr Cardiol. 2015 Mar;36(3):516-23.

Ryan TD, Jefferies JL, Zafar F, Lorts A, Morales DL. The evolving role of the total artificial heart in the management of end-stage congenital heart disease and adolescents. ASAIO J. 2015 Jan-Feb;61(1):8-14.

Moore RA, Madueme PC, Lorts A, Morales DL, Taylor MD. Virtual implantation evaluation of the total artificial heart and compatibility: Beyond standard fit criteria. J Heart Lung Transplant. 2014 Nov;33(11):1180-3.

Lorts A, Zafar F, Adachi I, Morales DL. Mechanical assist devices in neonates and infants. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2014;17(1):91-5.

Ryan TD, Jefferies JL, Sawnani H, Wong BL, Gardner A, Del Corral M, Lorts A, Morales DL. Implantation of the HeartMate II and HeartWare left ventricular assist devices in patients with duchenne muscular dystrophy: lessons learned from the first applications. ASAIO J. 2014 Mar-Apr;60(2):246-8.

David L.S. Morales, MD Chief of Cardiovascular Surgery, Heart Institute, Cardiothoracic Surgery 513-803-9150 david.morales@cchmc.org

Thomas D. Ryan, MD, PhD Heart Failure, Transplant, VAD Physician 513-803-2913 thomas.ryan@cchmc.org

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Thomas D. Ryan, MD, PhD

Heart Failure, Transplant, VAD Physician

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-803-2913

Email thomas.ryan@cchmc.org

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Clinical

Cardiomyopathy; advanced heart failure; heart transplantation; mechanical circulatory support and transplant

Research

Development of cardiomyopathy in at risk populations, including Duchenne muscular dystrophy and other genetic cardiomyopathies, and anthracycline exposure.

Biography

Thomas D Ryan, MD, PhD, was born and raised in Wichita, KS and graduated magna cum laude from Wichita State University in 1996 with a BS in biological sciences.

In 1997 he began training in the MD/PhD program at the University of Alabama at Birmingham, and studied the molecular, cellular, and whole organ aspects of cardiac remodeling in a rat model of volume overload. His general pediatrics residency training took place at Cincinnati Children’s Hospital Medical Center from 2006-2009, as did his pediatric cardiology fellowship training from 2009-2012 and advanced fellowship in Pediatric Heart Failure/Transplant from 2012-2013. His clinical and research interests focus on heart failure, cardiomyopathy, cardiac transplantation, and mechanical circulatory support.

BS: Wichita State University, Wichita, KS, 1996.

PhD: University of Alabama at Birmingham, Birmingham, AL, 2004.

MD: University of Alabama at Birmingham, Birmingham, AL, 2005.

Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2006-2009.

Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2009-2012.

Advanced Fellowship: Pediatric Heart Failure/Transplant, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2012-2013.

Certification: American Board of Pediatrics, 2010; American Board of Pediatrics, Sub-board of Pediatric Cardiology, 2012.

Ryan TD, Jefferies JL, Chin C, Sticka JJ, Taylor MD, Harris R, Moore J, Goodridge E, Mount L, Bolyard AA, Otto B, Jones A, Shimamura A, Davies S, Myers K. Abnormal circumferential strain measured by echocardiography is present in patients with shwachman-diamond syndrome despite normal shortening fraction. Pediatr Blood Cancer. 2015 Mar 2.

Ryan TD, Jefferies JL, Wilmot I. Managing heart failure in adults with congenital heart disease. Curr Treat Options Cardiovasc Med. 2015 Feb;17(2):376.

Villa CR, Ryan TD, Collins JJ, Taylor MD, Lucky AW, Jefferies JL. Left ventricular non-compaction cardiomyopathy associated with epidermolysis bullosa simplex with muscular dystrophy and PLEC1 mutation. Neuromuscul Disord. 2015 Feb;25(2):165-8.

Dandoy CE, Davies SM, Hirsch R, Chima RS, Paff Z, Cash M, Ryan TD, Lane A, El-Bietar J, Myers KC, Jodele S. Abnormal echocardiography seven days after stem cell transplant may be an early indicator of thrombotic microangiopathy. Biol Blood Marrow Transplant. 2015 Jan;21(1):113-8.

Ryan TD, Jefferies JL, Zafar F, Lorts A, Morales DLSM. The evolving role of the total artificial heart in the management of end-stage congenital heart disease and adolescents. ASAIO Journal. 2015 Jan-Feb;61(1):8-14.

Chin C, Ryan TD, Castleberry CD. Transplantation in the highly sensitized pediatric patient. Circulation. 2014 Jun 3;129:2313-19.

Ryan TD, Jefferies JL, Sawnani H, Wong BL, Gardner A, Del Corral M, Lorts A, Morales DLS. Implantation of the HeartMate II and HeartWare left ventricular assist devices in patients with Duchenne muscular dystrophy: lessons learned from the first applications. ASAIO Journal. 2014 Mar-Apr;60(2):246-8.

Ryan TD, Taylor MD, Wojciech M, Cripe LH, Pratt J, King EC, Lao K, Grenier MA, Jefferies JL, Benson DW, Hor KH. Abnormal circumferential strain is present in young Duchenne muscular dystrophy patients. Pediatric Cardiol. 2013 Jun;34(5):1159-65.

Ryan TD, Ware SM, Lucky AW, Towbin JA, Jefferies JL, Hinton RB. Left ventricular noncompaction cardiomyopathy and aortopathy in a patient with recessive dystrophic epidermolysis bullosa. Circ Heart Fail. 2012 Sep 1;5(5):e81-2.

Ryan TD, Rothstein EC, Aban I, Tallaj JA, Husain A, Lucchesi PA, Dell'Italia LJ. Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede cardiomyocyte elongation in rats with volume overload. J Am Coll Cardiol. 2007 Feb 20;49(7):811-21.

Shelly L. Stark, MSN, APRN, CNP Acute Care Pediatric Nurse Practitioner, Heart Failure/Cardiomyopathy/Transplant, Heart Institute 513-803-9011 shelly.stark@cchmc.org

BreAnn Taylor, PharmD, BCPS Clinical Pharmacy Specialist, Outpatient Cardiology, Division of Pharmacy 513-636-4292 breann.taylor@cchmc.org

James S. Tweddell, MD Executive Co-Director, Heart Institute 513-803-8824 james.tweddell@cchmc.org

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James S. Tweddell, MD

Executive Co-Director, Heart Institute

Surgical Director, Heart Institute

Academic Affiliations

Professor, UC Department of Surgery

Phone 513-803-8824

Email james.tweddell@cchmc.org

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Clinical

Surgical emphases include congenital heart surgery in neonates, infants, children, teenagers and adults. Heart transplantation and mechanical circulatory support.

Research

Developing reliable and reproducible evidence-based perioperative management strategies to improve survival and developmental outcomes; novel monitoring techniques such as continuous venous oximetry and near infrared spectroscopy.

Biography

Dr. Tweddell leads the Heart Institute’s surgical team providing unparalleled surgical care and innovation for our patients and their families. Over the last 20 years, he built the pediatric cardiothoracic surgery program at the Medical College of Wisconsin, where he held the S. Bert Litwin Chair for Cardiothoracic Surgery position, served as medical director of pediatric cardiothoracic surgery at Children’s Hospital of Wisconsin and professor and chief for the Division of Cardiothoracic Surgery. Dr. Tweddell has an extensive list of vital research contributions, having authored more than 125 peer reviewed articles, published numerous books, chapters, invited reviews and editorials, and serving on multiple editorial boards and national committees.

Dr. Tweddell is the elite surgeon of his generation and has earned a worldwide reputation for outstanding clinical results based on team contributions to his outcomes. He decreased mortality following the Norwood procedure through the use of venous saturation monitoring and afterload reduction. In addition, Dr. Tweddell reduced interstage mortality of a single ventricle patient through the development of a home monitoring program.

MD: University of Cincinnati, Cincinnati, OH, 1985.

Residency: Intern and Second Year Resident in General Surgery, New York Medical Center, New York, NY, 1987.

Residency: Research Fellow in Cardiothoracic Surgery, Washington University Medical Center, St. Louis, MO, 1989.

Residency: Senior Resident and Chief Resident in General Surgery, Washington University Medical Center, St. Louis, MO, 1991.

Residency: Resident in Cardiothoracic Surgery, Washington University Medical Center, St. Louis, MO, 1993.

Fellowship: Fellow in Pediatric Cardiothoracic Surgery, Washington University Medical Center, St. Louis, MO, 1993.

Jacobs JP, O'Brien SM, Pasquali SK, Gaynor JW, Mayer JE Jr, Karamlou T, Welke KF, Filardo G, Han JM, Kim S, Quintessenza JA, Pizarro C, Tchervenkov CI, Lacour-Gayet F, Mavroudis C, Backer CL, Austin EH 3rd, Fraser CD, Tweddell JS, Jonas RA, Edwards FH, Grover FL, Prager RL, Shahian DM, Jacobs ML. The Society of Thoracic Surgeons Congenital Heart Surgery Database Mortality Risk Model: Part 2-Clinical Application. Ann Thorac Surg. 2015 Aug 3.

Tweddell JS. The Atrial Level Switch Operation: Lessons Old and New. Circulation. 2015 Jul 16.

Niebler RA, Shah TK, Mitchell ME, Woods RK, Zangwill SD, Tweddell JS, Berger S, Ghanayem NS. Ventricular Assist Device in Single-Ventricle Heart Disease and a Superior Cavopulmonary Anastomosis. Artif Organs. 2015 Jul 6.

Jacobsen RM, Earing MG, Hill GD, Barnes M, Mitchell ME, Woods RK, Tweddell JS. The Externally Supported Ross Operation: Early Outcomes and Intermediate Follow-Up. Ann Thorac Surg. 2015 Aug;100(2):631-8.

Ginde S, Lam J, Hill GD, Cohen S, Woods RK, Mitchell ME, Tweddell JS, Earing MG. Long-term outcomes after surgical repair of complete atrioventricular septal defect. J Thorac Cardiovasc Surg. 2015 Aug;150(2):369-74.

Buelow MW, Earing MG, Hill GD, Cohen SB, Bartz PJ, Tweddell JS, Ginde S. Tricuspid repair at pulmonary valve replacement does not alter outcomes in tetralogy of Fallot. Ann Thorac Surg. 2015 Mar;99(3):899-904.

Cox DA, Ginde S, Tweddell JS, Earing MG. Outcomes of a hepatitis C screening protocol in at-risk adults with prior cardiac surgery. World J Pediatr Congenit Heart Surg. 2014 Oct;5(4):503-6.

Samyn MM, Plymale JM, Cousineau AJ, Tweddell JS. TAPVR in a kindergartner presenting with fatigue. BMJ Case Rep. 2014 Oct 9;2014.

McCrindle BW, Li JS, Manlhiot C, Tweddell JS, Giglia TM, Massicotte MP, Monagle P, Krishnamurthy R, Mahaffey KW, Michelson AD, Verdun N, Almond CS, Newburger JW, Brandão LR, Esmon CT, Manco-Johnson MJ, Ichord R, Ortel TL, Chan AK, Portman R, Rose M, Strony J, Kaltman JR. Challenges and priorities for research: a report from the National Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH) Working Group on thrombosis in pediatric cardiology and congenital heart disease. Circulation. 2014 Sep 30;130(14):1192-203.

Mitchell ME, Rumman N, Chun RH, Rao A, Martin T, Beste DJ, Berens RJ, Parakininkas DE, Ghanayem NS, Hubert MJ, Uhing M, Simpson P, Sato TT, Tweddell JS, Kerschner JE. Anterior tracheal suspension for tracheobronchomalacia in infants and children. Ann Thorac Surg. 2014 Oct;98(4):1246-53.

Grants

PumpKIN Trial. Principle Surgical Investigator. National Institutes of Health. 2013-ongoing.

Targeted, Highly Sensitive, Non-Invasive Cardiac Transplant Rejection Monitoring. Co-Principal Investigator. National Institutes of Health. 2013-2018.

Berlin Heart Post Approval Study. Co-Principal Investigator. Berlin Heart Inc. Aug 2013-ongoing.

Ivan Wilmot, MD Heart Failure, Transplant, Ventricular Assist Device Physician 513-803-2913 ivan.wilmot@cchmc.org

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Ivan Wilmot, MD

Heart Failure, Transplant, Ventricular Assist Device Physician

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-803-2913

Email ivan.wilmot@cchmc.org

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Clinical

Advanced heart failure; transplantation; mechanical circulatory support and transplant; cardiomyopathy

Research

Care of children with advanced heart failure requiring mechanical circulatory support bridge to transplant; quality of life in children with heart failure, transplant and mechanical circulatory support (MCS); advanced strain imaging in evaluation of ventricular function in pediatric heart transplant patients.

Biography

Ivan Wilmot, MD, graduated summa cum laude from Louisiana State University with a Bachelor of Science in zoology.

In 1998 he began medical school at Emory University. His general pediatrics residency training took place at the Emory Affiliated Hospitals from 2002 to 2006. He completed his pediatric cardiology fellowship training from 2006 to 2009, and advanced fellowship in heart failure and transplant from 2009 to 2010.

His clinical and research interests focus on heart failure, cardiac transplantation and mechanical circulatory support (MCS).

BS: Louisiana State University, Baton Rouge, LA, 1998.

MD: Emory University School of Medicine, Atlanta, GA, 2002.

Residency: Emory Affiliated Hospitals, Atlanta, GA, 2005; Chief Resident: Emory Affiliated Hospitals, Atlanta, GA, 2006.

Fellowship: Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, 2009.

Advanced Fellowship: Heart Failure and Transplant, Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, 2010.

Certification: American Board of Pediatrics; American Board of Pediatrics Sub-board of Pediatric Cardiology.