Stem Cell Biology
Research in this area focuses on identifying and manipulating stem cells to replace tissues damaged by disease and injury. It is estimated that many diseases could ultimately be treated with stem cell-based therapies.
Scientists here investigate new ways to use adult and embryonic stem cells to promote regeneration and to generate tissues for transplantation to cure childhood disease. The Cincinnati Children's Research Foundation has initiated a seven-year expansion project that includes a new state-of-the-art research building and a commitment to hire new faculty members that study stem cell biology.
Faculty
Steve Danzer, PhD, Assistant Professor
Elucidating the role of neurogenesis in the development of epilepsy. [Visit the Danzer Lab]
James C. Mulloy, PhD, Associate Professor
Molecular mechanisms involved in leukemia induction and maintenance; mouse modeling of leukemia using primary human blood stem cells [Visit the Mulloy Lab]
Masato Nakafuku, MD, PhD, Professor
Molecular control of neural stem cells in development and regeneration of mammalian central nervous system [Visit the Nakafuku Lab]
Satoshi Namekawa, PhD, Assistant Professor
The long-term goal of our research is to understand the mechanisms and evolution of epigenetic events during mammalian germ cell development [Visit Reproductive Sciences]
Yuya Ogawa, PhD
Molecular mechanisms of long noncoding RNA-mediated epigenetic gene regulation during mammalian development; X-chromosome inactivation using ex vivo differentiation system with mouse ES cells. [Visit Reproductive Sciences]
Sarah Pixley, PhD, Associate Professor
Neurogenesis and neurotrophic interactions in olfactory neuron cultures and in vivo; neuronal stem cells [Visit the Pixley Lab]
Steven Potter, PhD, Professor
Studies of homeobox genes that control mammalian development using gene targeting and transgenic mice [Visit the Potter Lab]
Jim Wells, PhD, Associate Professor
Endoderm organogenesis and promoting the differentiation of embryonic stem cells into therapeutic endoderm derivatives. [Visit the Wells Lab]
Susanne Wells, PhD, Associate Professor
Papilloma virus and cervical cancer [Visit the Susanne Wells Lab]
Jeffrey A. Whitsett, MD, Professor
Organ morphogenesis, gene regulation, cell differentiation, respiratory disease [Visit the Whitsett Lab]
Chunyue Yin, PhD, Assistant Professor
The molecular and cellular mechanisms underlying liver development and disease pathogenesis using the zebrafish model organism. [Visit the Yin Lab]
Yi Zheng, PhD, Professor
Molecular mechanisms of Rho GTPase signal transduction. Development of novel therapeutic reagents to inhibit Rho pathways related to human pathological conditions [Visit Experimental Hematology and Cancer Biology]
Contact Us
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
