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Michael P. Jankowski, PhD

Academic Affiliation

Assistant Professor

Phone 513-803-7966

Email michael.jankowski@cchmc.org

Specialties
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Chronic pain; neurodevelopmental diseases

Visit the Jankowski Lab.

Biography
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Dr. Jankowski joined the faculty in the Department of Anesthesia/Division of Pain Management at Cincinnati Children’s Hospital Medical Center within the University of Cincinnati College of Medicine in November of 2011. Previously, he had been awarded both pre-doctoral (2006) and postdoctoral National Research Service Awards (2008) prior to becoming faculty at the University of Pittsburgh. While a member of the Department of Neurobiology at the University of Pittsburgh, he presented several public presentations including one seminar titled, “Interfering with the Molecular Mechanisms of Pain” at the Center for Neuroscience at the University of Pittsburgh’s  Annual Retreat in 2009, and another titled, ”Preparation and Delivery of siRNAs to Sensory Neurons” at the International Association for the Study of Pain’s Satellite Symposium: “Nociceptors: New Biology” in Edinburgh, Scotland in 2008.

Dr. Jankowski has also been the recent recipient of two NIH grants in 2013: one from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (R03HD077483) and another from the National Institute of Arthritis, and Musculoskeletal and Skin Diseases (R01AR064551). He also is a Rita Allen Scholar and was recently named a Cincinnati Children's Trustee Scholar. In addition, Dr. Jankowski is on the training faculty in the graduate program in neuroscience, and in the Molecular and Developmental Biology Graduate Program. He is currently a member of the Society for Neuroscience, the International Association for the Study of Pain, the Society for Pediatric Anesthesia, and the American Pain Society. 

Education and Training
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MS: Neuroscience, University of Pittsburgh, Pittsburgh, PA, 2003.

PhD: Neurobiology, University of Pittsburgh, Pittsburgh, PA, 2006.

Postdoctoral Training: University of Pittsburgh, Pittsburgh, PA, 2006-2010.

Publications
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Ross JL, Queme LQ, Cohen EC, Green KG, Lu P, An S, Shank AT, Hudgins RC, Jankowski MP. Muscle IL1β drives ischemic myalgia via ASIC3-mediated sensory neuron sensitization. J Neurosci. 2016;36:6857-6871.

Queme LQ, Ross JL, Shank AT, Hudgins RC, Jankowski MP. Dual modulation of nociception and cardiovascular reflexes during peripheral ischemia through P2Y1 receptor dependent sensitization of muscle afferents. J Neurosci. 2016;36:19-30.

Wu LM, Wang J, Conidi A, Zhao C, Haibo W, Ford ZK, Zhang L, Zweir C, Ayee BG, Maurel P, Zwijsen A, Chan J, Jankowski, MP, Huylebroeck D, Lu QR. Zeb2 Recruits HDAC-NuRD to Inhibit Notch and Controls Schwann Cell Differentiation and Remyelination. Nature Neurosci. 2016 Aug;19(8):1060-1072.

Molliver DC, Rau KK, Jankowski MP, Soneji DJ, Baumbauer KM, Koerber HR. Deletion of the murine ATP/UTP receptor P2Y2 alters mechanical and thermal response properties in a population of TRPV1-containing cutaneous afferents. Neuroscience. 2016 Jul 5;332:223-230.

Shabnam P, Xiaona L, Sameer K, Anderson J, Fumiyasu I, Wujuan S, Ciraolo G, Ratner N, Setchell K, Yoshida Y, Jankowski MP, Dasgupta B. The tumor suppressor LKB1 regulates myelination through mitochondrial metabolism. Nature Comm. 2014;5:4993.

Ross JL, Queme LQ, Shank AT, Hudgins RC, Jankowski MP. Sensitization of group III and IV muscle afferents after ischemia and reperfusion injury. J Pain. 2014;15:1257-1270.

Jankowski MP, Ross JL, Weber JD, Lee FL, Shank AT, Hudgins RC. Age-dependent sensitization of cutaneous nociceptors during developmental inflammation. Mol Pain. 2014;10:34.

Jankowski MP, Rau KK, Ekmann KM, Anderson CE, Koerber HR. Comprehensive phenotyping of group III and IV muscle afferents in mouse. J Neurophys. 2013;109:2374-2381.

Jankowski MP, Anderson W, Anderson CE, Koerber HR. Dynamic changes in heat transducing channel TRPV1 expression regulate mechanically insensitive, heat sensitive C-fiber recruitment after axotomy and regeneration. J Neurosci. 2012;32:17869-73.

Li L, Rutlin M, Abraira V, Cassidy C, Jankowski MP, Luo W, Heintz N, Koerber HR, Woodbury CJ, Ginty DD. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 2011;147:1615-27.

Grants
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Mechanisms of muscle afferent sensitization after ischemia. Principal Investigator. National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. Sep 2013 – Sep 2018.

Growth hormone, pediatric pain and sensory development. Principal Investigator. Cincinnati Children's Hospital Medical Center. Sep 2015 - Sep 2016.

Linking sex differences in cardiovascular reflexes and pain perception. Sponsor. National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. Jul 2016 - Jul 2018. F31AR068896-01A1.

Role of GDNF in the dual modulation of nociception and cardiovascular reflexes during peripheral ischemia. Sponsor. American Heart Association. Jul 2016 - Jul 2018. 16POST29750004.

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