A photo of Rolf Stottmann.

Associate Professor, UC Department of Pediatrics

513-636-7136

Biography & Affiliation

Research Interests

Developmental neurobiology; genetics; animal models of human congenital defects

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Divisions

Human Genetics, Developmental Biology

Education

BS: University of Maryland, College Park, MD, 1995.

MS: University of Maryland, College Park, MD, 1997.

PhD: Duke University School of Medicine, Durham, NC, 2004.

Postdoctoral Training: Brigham & Women’s Hospital; Harvard Medical School.

Publications

Nubp2 is required for cranial neural crest survival in the mouse. DiStasio, A; Paulding, D; Chaturvedi, P; Stottmann, RW. Developmental Biology. 2020; 458:189-199.

Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants. Snedeker, J; Jr, GW J; Paulding, DF; Abdelhamed, Z; Prows, DR; Stottmann, RW. PLoS Genetics. 2019; 15:e1008467-e1008467.

Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis. Magini, P; Smits, DJ; Vandervore, L; Schot, R; Columbaro, M; Kasteleijn, E; van der Ent, M; Palombo, F; Lequin, MH; Dremmen, M; et al. The American Journal of Human Genetics. 2019; 105:689-705.

Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence. Lukacs, M; Gilley, J; Zhu, Y; Orsomando, G; Angeletti, C; Liu, J; Yang, X; Park, J; Hopkin, RJ; Coleman, MP; et al. Experimental Neurology. 2019; 320:112961-112961.

Differential requirements of tubulin genes in mammalian forebrain development. Bittermann, E; Abdelhamed, Z; Liegel, RP; Menke, C; Timms, A; Beier, DR; Stottmann, RW. PLoS Genetics. 2019; 15:e1008243-e1008243.

Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival. Lukacs, M; Roberts, T; Chatuverdi, P; Stottmann, RW. eLife. 2019; 8.

Using human sequencing to guide craniofacial research. Liegel, RP; Finnerty, E; Blizzard, L; DiStasio, A; Hufnagel, RB; Saal, HM; Sund, KL; Prows, CA; Stottmann, RW. Genesis: the Journal of Genetics and Development. 2019; 57:e23259-e23259.

A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Abdelhamed, Z; Vuong, SM; Hill, L; Shula, C; Timms, A; Beier, D; Campbell, K; Mangano, FT; Stottmann, RW; Goto, J. Development (Cambridge). 2018; 145:dev154500-dev154500.

Ttc21b is required in Bergmann glia for proper granule cell radial migration. Driver, AM; Shumrick, C; Stottmann, RW. Journal of Developmental Biology. 2017; 5:18-18.

Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly. DiStasio, A; Driver, A; Sund, K; Donlin, M; Muraleedharan, RM; Pooya, S; Kline-Fath, B; Kaufman, KM; Prows, CA; Schorry, E; et al. Human Molecular Genetics. 2017; 26:4836-4848.