A photo of Kavisha Arora.

Instructor, UC Department of Pediatrics

513-803-7628

Biography & Affiliation

Research Interests

Disease-modifying cellular and molecular mechanisms in Cystic Fibrosis and GI-related disorders; airway mucociliary clearance in Cystic Fibrosis

Academic Affiliation

Instructor, UC Department of Pediatrics

Department

Pulmonary Medicine

Education

PhD: University of Tennessee Health Science Center, Memphis, TN, 2013.

Publications

Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis. Zeng, C; Vanoni, S; Wu, D; Caldwell, JM; Wheeler, JC; Arora, K; Noah, TK; Waggoner, L; Besse, JA; Yamani, AN; et al. Journal of Allergy and Clinical Immunology. 2018; 142:1843-1855.

AC6 is the major adenylate cyclase forming a diarrheagenic protein complex with cystic fibrosis transmembrane conductance regulator in cholera. Thomas, A; Ramananda, Y; Mun, K; Naren, AP; Arora, K. The Journal of biological chemistry. 2018; 293:12949-12959.

Personalized medicine in CF: from modulator development to therapy for cystic fibrosis patients with rare CFTR mutations. Harutyunyan, M; Huang, Y; Mun, K; Yang, F; Arora, K; Naren, AP. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2018; 314:L529-L543.

Guanylate cyclase 2C agonism corrects CFTR mutants. Arora, K; Huang, Y; Mun, K; Yarlagadda, S; Sundaram, N; Kessler, MM; Hannig, G; Kurtz, CB; Silos-Santiago, I; Helmrath, M; et al. JCI insight. 2017; 2.

Epithelial Gpr116 regulates pulmonary alveolar homeostasis via G(q/11) signaling. Brown, K; Filuta, A; Ludwig, M; Seuwen, K; Jaros, J; Vidal, S; Arora, K; Naren, AP; Kandasamy, K; Parthasarathi, K; et al. JCI insight. 2017; 2.

Pharmacological Correction of Cystic Fibrosis: Molecular Mechanisms at the Plasma Membrane to Augment Mutant CFTR Function. Arora, K; Naren, AP. Current Drug Targets. 2016; 17:1275-1281.

Personalized medicine in cystic fibrosis: genistein supplementation as a treatment option for patients with a rare S1045Y-CFTR mutation. Arora, K; Yarlagadda, S; Zhang, W; Moon, C; Bouquet, E; Srinivasan, S; Li, C; Stokes, DC; Naren, AP. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2016; 311:L364-L374.

Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration. Sinha, C; Arora, K; Naren, AP. Jove-Journal of Visualized Experiments. 2016; 2016.

Drug-induced secretory diarrhea: A role for CFTR. Moon, C; Zhang, W; Sundaram, N; Yarlagadda, S; Reddy, VS; Arora, K; Helmrath, MA; Naren, AP. Pharmacological Research. 2015; 102:107-112.

Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis. Arora, K; Sinha, C; Zhang, W; Moon, CS; Ren, A; Yarlagadda, S; Dostmann, WR; Adebiyi, A; Haberman, Y; Denson, LA; et al. The American journal of pathology. 2015; 185:2790-2804.