Identification of anoctamin 1 (ANO1) as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis.
Vanoni, S; Zeng, C; Marella, S; Uddin, J; Wu, D; Arora, K; Ptaschinski, C; Que, J; Noah, T; Waggoner, L; et al.
Journal of Allergy and Clinical Immunology.
2020;
145:239-254.e2.
Targeting DNAJB9, a novel ER luminal co-chaperone, to rescue ΔF508-CFTR.
Huang, Y; Arora, K; Mun, KS; Yang, F; Moon, C; Yarlagadda, S; Jegga, A; Weaver, T; Naren, AP.
Scientific Reports.
2019;
9.
Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders.
Mun, KS; Arora, K; Huang, Y; Yang, F; Yarlagadda, S; Ramananda, Y; Abu-El-Haija, M; Palermo, JJ; Appakalai, BN; Nathan, JD; et al.
Nature Communications.
2019;
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IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis.
Noah, TK; Knoop, KA; McDonald, KG; Gustafsson, JK; Waggoner, L; Vanoni, S; Batie, M; Arora, K; Naren, AP; Wang, Y; et al.
Journal of Allergy and Clinical Immunology.
2019;
144:1058-1073.e3.
Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis.
Zeng, C; Vanoni, S; Wu, D; Caldwell, JM; Wheeler, JC; Arora, K; Noah, TK; Waggoner, L; Besse, JA; Yamani, AN; et al.
Journal of Allergy and Clinical Immunology.
2018;
142:1843-1855.
AC6 is the major adenylate cyclase forming a diarrheagenic protein complex with cystic fibrosis transmembrane conductance regulator in cholera.
Thomas, A; Ramananda, Y; Mun, K; Naren, AP; Arora, K.
Journal of Biological Chemistry.
2018;
293:12949-12959.
Personalized medicine in CF: from modulator development to therapy for cystic fibrosis patients with rare CFTR mutations.
Harutyunyan, M; Huang, Y; Mun, K; Yang, F; Arora, K; Naren, AP.
American Journal of Physiology - Lung Cellular and Molecular Physiology.
2018;
314:L529-L543.
PP-2, a src-kinase inhibitor, is a potential corrector for F508del-CFTR in cystic fibrosis.
Wang, Y; Arora, K; Yang, F; Shin, W; Chen, J; Kihara, D; Naren, AP; Jegga, AG.
Cold Spring Harbor Laboratory.
2018.
Guanylate cyclase 2C agonism corrects CFTR mutants.
Arora, K; Huang, Y; Mun, K; Yarlagadda, S; Sundaram, N; Kessler, MM; Hannig, G; Kurtz, CB; Silos-Santiago, I; Helmrath, M; et al.
JCI insight.
2017;
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Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling.
Brown, K; Filuta, A; Ludwig, M; Seuwen, K; Jaros, J; Vidal, S; Arora, K; Naren, AP; Kandasamy, K; Parthasarathi, K; et al.
JCI insight.
2017;
2.