Mekbib Altaye, PhD

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-5849

Fax 513-636-7509


Design and analysis of correlated data. This includes developing inference procedures for intraclass correlation, and kappa statistic for binary and polynomial outcomes. Recent research interest includes modeling issues associated with high dimensional data that arise from fMRI, MRI and microbiome studies.

Dr. Altaye has published more than 60 peer-reviewed articles and more than 70 abstracts/posters. He has been invited to present his work in national meetings and co-author a book chapter. He has been a co-investigator, collaborator or biostatistician in more than 20 NIH funded projects. Dr. Altaye provides support for researchers in multiple divisions as well as for the Center for Clinical and Translational Sciences and Training (CCTST). He taught biostatistics courses for the Master of Science Clinical and Translational Research program. He has obtained travel awards to attend workshops from NSF and NIH. One of his articles received a Caffey award for best clinical science or education paper from the Pediatric Radiology Society.


PhD: The University of Western Ontario, London, Canada, 1998.

MSc: Oklahoma State University, Stillwater, OK, 1991.

BSc: Addis Ababa Universtiy, Addis Ababa, Ethiopia, 1983.

View PubMed Publications

Szaflarski JP, Rajagopal A, Altay M, Byars AW, Jacola L, Schmithorst VJ, Schaprio MB, Plante E, Holland SK. Left-handedness and language lateralization in children. Brain Research. 1433: 85-97. 2012.

Cecil KM, Dietrich KN, Altaye M, Egelhoff JC, Lindquist DM, Brubaker CJ, Lanphear BP. Proton magnetic resonance spectroscopy in adults with childhood lead exposure. Environmental Health Perspective. Mar;119(3):403-8. 2011.

Yuan W, Altaye M, Ret J, Schmithorst VJ Byars AW, Plante E, Holland SK. Quantification of children’s head motion in various fMRI language tasks. Human Brain Mapping. 30(5): 1481-9. 2009.

Langberg, JM., Epstein, JN., Altaye M., Molina, B., Arnold, E., Vitiello, B. The transition to middle school is associated with changes in the developmental trajectory of ADHD symptomatology in young adolescents with ADHD. Journal of Clinical Child and Adolescent Psychology. 37(3): 651-63. 2008.

Eaton KP, Szaflarski JP, Altaye M, Ball AL, Kissela BM, Banks C, Holland SK. Reliability of fMRI for studies of language in post-stroke aphasia subjects. NeuroImage. 41(2): 311-22. 2008.

Wilke M, Holland SK, Altaye M, Gaser C. Template-o-matic: a toolbox for creating customized pediatric templates. NeuroImage. 41(3): 903-13. 2008.

Altaye M, Holland SK, Wilke M, Gaser C. Infant brain probability templates for MRI segmentation and normalization. NeuroImage. 43(4): 721-30. 2008.

Szaflarski JP, Schmithorst VJ, Altaye M, Byars AW, Rett J, Plante E, Holland SK. A longitudinal fMRI study of language development in children age 5-11. Annals of Neurology. 59(5): 796-807. 2006.

Altaye M, Donner A, Eliasziw M. A general goodness of fit approach for inference procedures concerning the kappa statistic. Statistics in Medicine. 16: 2479-2488. 2001.

Altaye M, Donner A, Klar N. Inference procedures for assessing interobserver agreement among multiple raters. Biometrics. 57: 584-588. 2001.

Imaging the effect of centrotemporal spikes and seizures. Biostatistician. NIH/NIND. Sep 2011-Jun 2016.