A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption.
Shima, K; Arumugam, P; Sallese, A; Horio, Y; Ma, Y; Trapnell, C; Wessendarp, M; Chalk, C; McCarthy, C; Carey, BC; et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology.
2022;
322:L438-L448.
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation.
Wessendarp, M; Watanabe-Chailland, M; Liu, S; Stankiewicz, T; Ma, Y; Kasam, RK; Shima, K; Chalk, C; Carey, B; Rosendale, L; et al.
Mitochondrion.
2022;
62:85-101.
Early Results from a Phase 1/2 Study of Aru-1801 Gene Therapy for Sickle Cell Disease (SCD): Manufacturing Process Enhancements Improve Efficacy of a Modified Gamma Globin Lentivirus Vector and Reduced Intensity Conditioning Transplant.
Grimley, M; Asnani, M; Shrestha, A; Felker, S; Lutzko, C; Arumugam, PI; Witting, S; Knight-Madden, J; Niss, O; Quinn, CT; et al.
Blood.
2020;
136:20-21.
Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia.
Hudock, KM; Collins, MS; Imbrogno, M; Snowball, J; Kramer, EL; Brewington, JJ; Gollomp, K; McCarthy, C; Ostmann, AJ; Kopras, EJ; et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology.
2020;
319:L137-L147.
FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation.
Black, M; Arumugam, P; Shukla, S; Pradhan, A; Ustiyan, V; Milewski, D; Kalinichenko, VV; Kalin, TV.
Molecular Biology of the Cell.
2020;
31:1411-1424.
Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra-/- Mice.
Arumugam, P; Suzuki, T; Shima, K; McCarthy, C; Sallese, A; Wessendarp, M; Ma, Y; Meyer, J; Black, D; Chalk, C; et al.
Molecular Therapy.
2019;
27:1597-1611.
Elimination of the fibrinogen integrin αMβ2-binding motif improves renal pathology in mice with sickle cell anemia.
Nasimuzzaman, M; Arumugam, PI; Mullins, ES; James, JM; VandenHeuvel, K; Narciso, MG; Shaw, MA; McGraw, S; Aronow, BJ; Malik, P.
Blood Advances.
2019;
3:1519-1532.
Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis.
McCarthy, C; Lee, E; Bridges, JP; Sallese, A; Suzuki, T; Woods, JC; Bartholmai, BJ; Wang, T; Chalk, C; Carey, BC; et al.
Nature Communications.
2018;
9.
Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential.
Goodman, MA; Arumugam, P; Pillis, DM; Loberg, A; Nasimuzzaman, M; Lynn, D; van der Loo, JC M; Dexheimer, PJ; Keddache, M; Jr, BT R; et al.
Journal of Virology.
2018;
92.
Targeting cholesterol homeostasis in lung diseases.
Sallese, A; Suzuki, T; McCarthy, C; Bridges, J; Filuta, A; Arumugam, P; Shima, K; Ma, Y; Wessendarp, M; Black, D; et al.
Scientific Reports.
2017;
7.