Sandra Andorf.

Assistant Professor, UC Department of Pediatrics

513-517-7132

Biography & Affiliation

Biography

Sandra Andorf, PhD, is a computational biologist with particular interest in computational immunology. She received her PhD in bioinformatics from the University of Potsdam, Germany, in 2011. Her professional development path has led her from biology, to working in a translational bioinformatics lab during her postdoc, to focusing on computational and statistical approaches in the intersection of clinical and immunological research.

Research Interests

Computational immunology; biomedical informatics; publicly available clinical data; food allergy

Academic Affiliation

Assistant Professor, UC Department of Pediatrics

Divisions

Biomedical Informatics, Allergy and Immunology

Education

BS: Westphalian University of Applied Sciences, Germany, 2005.

MS: Westphalian University of Applied Sciences, Germany, 2007.

PhD: University of Potsdam, Germany, 2011.

Publications

Selected Publication

Global metabolic profiling to model biological processes of aging in twins. Bunning, BJ; Contrepois, K; Lee-McMullen, B; Dhondalay, GK R; Zhang, W; Tupa, D; Raeber, O; Desai, M; Nadeau, KC; Snyder, MP; et al. Aging Cell. 2020; 19.

A Phase 2 Randomized Controlled Multisite Study Using Omalizumab-facilitated Rapid Desensitization to Test Continued vs Discontinued Dosing in Multifood Allergic Individuals. Andorf, S; Purington, N; Kumar, D; Long, A; O'Laughlin, KL; Sicherer, S; Sampson, H; Cianferoni, A; Whitehorn, TB; Petroni, D; et al. EClinicalMedicine. 2019; 7:27-38.

MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data. Hu, Z; Jujjavarapu, C; Hughey, JJ; Andorf, S; Lee, H; Gherardini, PF; Spitzer, MH; Thomas, CG; Campbell, J; Dunn, P; et al. Cell Reports. 2018; 24:1377-1388.

Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial. Andorf, S; Purington, N; Block, WM; Long, AJ; Tupa, D; Brittain, E; Spergel, AR; Desai, M; Galli, SJ; Nadeau, KC; et al. The Lancet Gastroenterology and Hepatology. 2018; 3:85-94.

Association of Clinical Reactivity with Sensitization to Allergen Components in Multifood-Allergic Children. Andorf, S; Borres, MP; Block, W; Tupa, D; Bollyky, JB; Sampath, V; Elizur, A; Lidholm, J; Jones, JE; Galli, SJ; et al. Journal of Allergy and Clinical Immunology-In Practice. 2017; 5:1325-1334.e4.

Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study. Chinthrajah, RS; Purington, N; Andorf, S; Long, A; O'Laughlin, KL; Lyu, SC; Manohar, M; Boyd, SD; Tibshirani, R; Maecker, H; et al. The Lancet. 2019; 394:1437-1449.

Proteasome-dependent regulation of distinct metabolic states during long-term culture of human iPSC-derived cardiomyocytes. Ebert, A; Joshi, AU; Andorf, S; Dai, Y; Sampathkumar, S; Chen, H; Li, Y; Garg, P; Toischer, K; Hasenfuss, G; et al. Circulation Research. 2019; 125:90-103.

A pilot study showing a stronger H1N1 influenza vaccination response during pregnancy in women who subsequently deliver preterm. Andorf, S; Bhattacharya, S; Gaudilliere, B; Shaw, GM; Stevenson, DK; Butte, AJ; Sirota, M. Journal of Reproductive Immunology. 2019; 132:16-20.

Analysis of a Large Standardized Food Challenge Data Set to Determine Predictors of Positive Outcome Across Multiple Allergens. Sindher, S; Long, AJ; Purington, N; Chollet, M; Slatkin, S; Andorf, S; Tupa, D; Kumar, D; Woch, MA; O'Laughlin, KL; et al. Frontiers in Immunology. 2018; 9.

Eliciting Dose and Safety Outcomes From a Large Dataset of Standardized Multiple Food Challenges. Purington, N; Chinthrajah, RS; Long, A; Sindher, S; Andorf, S; O'Laughlin, K; Woch, MA; Scheiber, A; Assa'ad, A; Pongracic, J; et al. Frontiers in Immunology. 2018; 9.