Allergy and Immunology Research

  

Our Mission

To improve the health of children with allergic and immune conditions through innovative research, outstanding clinical care and education of the current and next generation of leaders in healthcare and research.

Fundamental Studies

We focus on uncovering the molecular mechanisms (steps) of inflammation, primarily those involved in allergic and other immune-mediated disorders.

Translational Investigation

We concentrate on discovering key processes in the initiation and propagation of allergic and other immune-mediated responses in the lung (asthma), skin (eczema), upper respiratory tract (allergic rhinitis) and gastrointestinal tract (especially eosinophilic gastrointestinal disordersinflammatory bowel disease and food allergy) as well as systemically (anaphylaxis). Molecular pathways involved in macrophage activation syndrome (perforin mutations) and hypereosinophilic syndrome (IL-5 and activated tyrosine kinases) are primary focus areas. 

Clinical Trials

We focus on uncovering clinical, genetic and therapeutic principles concerning asthma, eosinophilic disorders (e.g., eosinophilic esophagitis and hypereosinophilic syndrome), macrophage activation syndrome and food allergy. Innovative clinical trials, based on fundamental and translational laboratory findings, are highly prioritized.

Our Clinic

Image of esophagus.
Learn more about our clinic. We offer comprehensive care for children with allergic and immunologic disorders as well as opportunities for clinical research studies.  Read More

Research Collaborations

Image of neutrophils.
Our investigators conduct studies in collaboration with outstanding researchers locally, nationally and internationally. Read More

Research and Training Details

Faculty15
Joint Appointment Faculty3
Research Fellows and Post Docs6
Research Graduate Students15
Direct Annual Grant Support$4,000,764
Direct Annual Industry Support$322,821
Publications45

Clinical Activities and Training

Staff Physicians2
Clinical Fellows7
Inpatient Encounters452
Outpatient Encounters6,614