A photo of Marc Rothenberg.

Director, Division of Allergy and Immunology

Director, Cincinnati Center for Eosinophilic Disorders

Professor, UC Department of Pediatrics

513-803-0257

513-636-3310

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My Biography & Research

Biography

Dr. Rothenberg is director of the Division of Allergy and Immunology at Cincinnati Children's Hospital Medical Center and the Bunning Professor of Pediatrics at Cincinnati Children’s within the University of Cincinnati College of Medicine. He graduated summa cum laude with highest honors in chemistry and biochemistry from Brandeis University. He then completed the MD/PhD program at Harvard Medical School under Dr. Frank Austen, conducting studies on eosinophil hematopoiesis, as he developed the first culture system for human eosinophils. After completing residency at Children’s Hospital, Boston, Dr. Rothenberg did a fellowship in allergy/immunology and hematology at Children’s Hospital. Dr. Rothenberg did post-doctorate training with Dr. Philip Leder, Harvard Medical School, where he cloned the eotaxin chemokine. After being faculty at Harvard Medical School for one year, he came to the University of Cincinnati and Cincinnati Children's, where he has helped build a top program in research, and his division is a leader in allergy and immunology.

His research is focused on molecular analysis of allergic inflammation, primarily on the pathogenesis of eosinophilia. His laboratory takes a multi-disciplinary approach including the development of preclinical murine models: genetics, genomics, molecular immunology, and biochemistry. Dr. Rothenberg’s awards include the 2007 E Mead Johnson Award from the Society of Pediatric Research, 2010 National Institutes of Health MERIT Award, being elected fellow of the American Association for the Advancement of Science American Society for Clinical Investigation, and recognition by Clarivate as a top 1% Highly Cited Researcher. His publications number over 400. He has served on review panels for journals/grant agencies including National Institutes of Health (NIH), Burroughs Trust, and Medical Research Council of the United Kingdom. He served for four years on the Advisory Council of National Institute of Allergy and Infectious Disease. He has been Associate Editor of the Journal of Allergy and Clinical Immunology since 2004. His research has been supported by sources including the NIH, Human Frontier Science Program Organization, Burroughs Wellcome Fund, Dana Foundation, Department of Defense, PCORI and the US-Israel Binational Fund.

Clinical Interests

Eosinophilia; eosinophilic disorders; asthma; allergy; food allergy

 

Research Interests

Eosinophils; chemokines

Academic Affiliation

Professor, UC Department of Pediatrics

Departments

Allergy and Immunology, Eosinophilic Disorders, Allergy and Immunology, Eosinophilic Disorders, Global Health

My Locations

My Education

MD, PhD: Harvard Medical School, Cambridge, MA, 1990.

Residency: Pediatrics, Children's Hospital, Boston, MA, 1991-1992.

Fellowship: Immunology / Allergy, Children's Hospital, Boston, MA, 1992-1994; Hematology / Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, MA, 1992-1995.

Certification: National Board of Medical Examiners, 1991; Board of Registration in Medicine, MA, 1992; American Board of Pediatrics, 1995, 2001, 2008; Ohio State Medical Board, 1997; American Board of Allergy and Immunology, 1997, 2006.

My Publications

Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. Muir, AB; Jensen, ET; Wechsler, JB; Menard-Katcher, P; Falk, GW; Aceves, SS; Furuta, GT; Dellon, ES; Rothenberg, ME; Spergel, JM. Journal of Allergy and Clinical Immunology-In Practice. 2019; 7:2434-2436.

Bagels and LOX in patients with eosinophilic esophagitis. Ben Baruch-Morgenstern, N; Shoda, T; Rothenberg, ME. Journal of Allergy and Clinical Immunology. 2019; 144:41-43.

17 beta-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling. Wheeler, JC; Vanoni, S; Zeng, C; Waggoner, L; Yang, Y; Wu, D; Uddin, J; Karns, R; Kottyan, L; Mukkada, V; et al. Journal of Allergy and Clinical Immunology. 2019; 143:2131-2146.

Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium. Pesek, RD; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, C; Falk, GW; Kuhl, J; Martin, EK; Magier, AZ; Ahmed, F; et al. The American Journal of Gastroenterology (Elsevier). 2019; 114:984-994.

Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia. DiTommaso, LA; Rosenberg, CE; Eby, MD; Tasco, A; Collins, MH; Lyles, JL; Putnam, PE; Mukkada, VA; Rothenberg, ME. Journal of Allergy and Clinical Immunology. 2019; 143:1928-1930.e3.

Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. Wen, T; Aronow, BJ; Rochman, Y; Rochman, M; Kiran, KC; Dexheimer, PJ; Putnam, P; Mukkada, V; Foote, H; Rehn, K; et al. Journal of Clinical Investigation. 2019; 129:2014-2028.

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Kottyan, LC; Maddox, A; Braxton, JR; Stucke, EM; Mukkada, V; Putnam, PE; Abonia, JP; Chehade, M; Wood, RA; Pesek, RD; et al. Genes and Immunity. 2019; 20:281-292.

Analysis of eosinophilic esophagitis in children with repaired congenital esophageal atresia. Krishnan, U; Lijuan, C; Andrew, GJ; Rothenberg, ME; Wen, T. Journal of Allergy and Clinical Immunology. 2019; 143:1455-1464.e2.

Mechanisms of gastrointestinal allergic disorders. Azouz, NP; Rothenberg, ME. Journal of Clinical Investigation. 2019; 130:1419-1430.

Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14. Miller, DE; Forney, C; Rochman, M; Cranert, S; Habel, J; Rymer, J; Lynch, A; Schroeder, C; Lee, J; Sauder, A; et al. G3-Genes Genomes Genetics. 2019; 9:g3.200901.2018-g3.200901.2018.