Allergy and Immunology
Clinical Trials

Clinical Trials for Allergies and Immunologic Disorders

We at the Division of Allergy and Immunology at Cincinnati Children’s are devoted to providing the best care for our patients. Our dedicated clinical staff partner with families to improve the health and quality of life of our patients. Our involvement in human research studies, also known as clinical trials, helps us to determine what treatments and strategies work best for our patients. Our division’s clinical trials team is dedicated to bringing cutting-edge therapies to our child and adult patients.

For more about our clinical trials, visit these clinicaltrials.gov webpages:

Allergy

Food Allergy

Eosinophilic Gastrointestinal Disease

Hypereosinophilic Syndrome

Ongoing Clinical Studies and Trials

CEGIR OMEGA Study for Patients with Eosinophilic Esophagitis (EoE), Eosinophilic Gastritis (EG), and Eosinophilic Colitis (EC)

What is the purpose of this study?

The purpose of this observational research study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EG, and EC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look.  We want to see if scores on standard questionnaires can give us an idea how well the person is doing.

Who can participate?

Children and adults ages 3-65 years that have been diagnosed with EoE, EG, or EC.

Details

General CEGIR OMEGA Description (PDF)
Adult (18-65 years) CEGIR OMEGA (PDF)
Pediatric (3-17 years) CEGIR OMEGA (PDF)

Who should I contact for more information?

ccedresearch@cchmg.org

Where can I find additional information?

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

Eosinophilic Gastrointestinal Disorders with Connective Tissue Disorders

Have you been diagnosed with an Eosinophilic Gastrointestinal Disorder and / or a Connective Tissue Disorder? The Cincinnati Center for Eosinophilic Disorders is conducting a research study designed to develop a better understanding and improved treatment plans for patients diagnosed with eosinophilic gastrointestinal disorders (EGID).

Who

Those of all ages who have been diagnosed with an EGID and a CTD (e.g., Marfan’s Syndrome, Ehlers-Danlos Syndrome, Hypermobility Syndrome, etc.).

What

Saliva samples and a brief medical history will be collected.

How

All study procedures will be done by phone, via mail and via the internet.

Why

To better understand the relationship between EGID and connective tissue disorders.

Contact

If you are interested in participating or have any questions, please contact ccedresearch@cchmc.org , 513-803-3078

Family Tree Study

Have several people in your family been diagnosed with an Eosinophilic Gastrointestinal Disorder (EGID)? The Cincinnati Center for Eosinophilic Disorders is conducting a research study designed to develop a better understanding and improved treatment plans for patients with eosinophilic gastrointestinal disorders (EGID).

Who

Families who have more than one member diagnosed with an EGID, particularly those families with three generations of diagnoses (e.g. grandparent, parent, and child), or families with cousins who have been diagnosed. 

What

Saliva samples and a brief medical history will be collected.

How

All study procedures will be done by phone, via mail, and via the internet.

Why

To better understand genetic factors that may influence how EGID is passed down through families.

Contact

If you are interested in participating or have any questions, please contact ccedresearch@cchmc.org

Twin Study  

Are you a twin diagnosed with an Eosinophilic Gastrointestinal Disorder (EGID)?   The Cincinnati Center for Eosinophilic Disorders is conducting a research study designed to develop a better understanding and improved treatment plans for patients with eosinophilic gastrointestinal disorders (EGID). 

Who

Identical and fraternal twins and multiple births of all ages with at least one sibling diagnosed with an EGID.

What

Saliva samples and a brief medical history will be collected.

How

All study procedures will be done by phone, via mail, and via the internet.

Why

To identify the genetic and environmental factors that contribute to the diagnosis of an EGID. 

Contact

If you are interested in participating or have any questions, please contact ccedresearch@cchmc.org

Common Allergy and Immunology Terms
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