Cincinnati Children’s was recently issued US Patent 9517238 B2 for the work of the inventors Marc E. Rothenberg and Mark Rochman. The invention provides methods of treating allergic inflammatory conditions using an anti-neurotrophin tyrosine kinase receptor 1 (NTRK1)-based therapeutic agent and related compositions and methods. The underlying research for this patent was conducted in the Rothenberg Lab.
Hosting a Food-Allergy-Friendly Holiday Party
FARE Joins with National Academies of Sciences, Engineering and Medicine in Call for Sweeping Changes to Improve Health, Quality of Life of Individuals With Food Allergies
We would like to mention that this vital work was made possible by so many contributors, including our colleague Carina Venter, PhD, RD, who served as a reviewer and contributor to this 500-page report on food allergy.
Trustee Grant Award
Ting Wen, PhD was awarded a Trustee Grant Award by Cincinnati Children’s to support his research.
Allergy Guideline Updating Efforts
We are proud of all the dedicated efforts made to move the guidelines for allergen introduction forward. Our colleague Amal H. Assa’ad, MD, comments in this NPR update, and our colleague Carina Venter, PhD, RD, is involved as a member of the scientific panel who are updating the guidelines that will be published in January on the National Institute of Allergy and Infectious Diseases (NIAID) website. Listen to or read the NPR segment (by Patti Neighmond). Read the Reuter's article (by Rob Goodier). Read Dr. Venter's JACI editorial about the LEAP study findings about early allergen consumption.
5 Tips for Packing a Well-Rounded Nut-free Lunch
LEAP Study Editorial
The Journal of Allergy and Clinical Immunology has included the LEAP (Learning Early About Peanut) nutrition study for its readership. Our colleague Carina Venter, PhD, RD, co-authored an editorial about the study findings about early allergen consumption.
CURED Foundation Donates for Eosinophilic Disorder Treatment and Research
The Campaign Urging Research for Eosinophilic Disease (CURED), a not-for-profit foundation dedicated to those suffering from eosinophilic disorders, has donated $100,000 to the Cincinnati Center for Eosinophilic Disorders (CCED), based at Cincinnati Children’s Hospital Medical Center. The CURED Foundation works extensively in supporting families and raising funds for research. One-hundred percent of funds raised by the CURED Foundation go to research for eosinophilic disorders. To date, CURED has contributed over 4 million dollars to research.
UC Summer Research Prepares Students for STEMM Careers
Two hundred college and high school students from the across the country participated in the 2016 Summer Undergraduate Research Fellowship (SURF) Capstone Poster Sessions sponsored by several programs at the UC College of Medicine and Cincinnati Children’s Hospital Medical Center as part of the SURF initiative, designed to provide rich research internship experiences for college students and high school seniors. All student winners were recognized during an awards ceremony. Marc Rothenberg, MD, PhD, Director of both the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s, gave the ceremony’s keynote speech. At its conclusion, he eulogized Olivia Erhardt, a 2015 SURF participant and Columbia University student who performed summer research in his laboratory at Cincinnati Children’s. Erhardt tragically lost her life in a bus accident during a medical mission trip to Honduras in January 2016.
Infants and Solid Food, an Introductory Course
. Carina Venter, PhD, RD, a research associate and dietician at Cincinnati Children's, discusses the transition from formula to solid food in infancy while navigating potential food allergies.
AAAAI Foundation & Dr. Donald Y.M. Leung/JACI Editors Faculty Development Award
Andrew W. Lindsley, MD, PhD, was interviewed about his recent award, the AAAAI Foundation and Dr. Donald Y.M. Leung/JACI Editors Faculty Development Award for his project investigating how ORMDL3 enhances macrophage function in asthma pathogenesis.
Darrel E. Goll Award for Scholarly Publication
Our collaborator, Leah C. Kottyan, PhD, received the Darrel E. Goll Award at the FASEB Biology of Calpains in Health and Disease Conference. This award recognizes the most outstanding publication in the field of calpains in the past three years, and we are proud for members of the Rothenberg Lab to have contributed to this outstanding work over the years. Their recent calpain publications include explore the tissue specificity and contribution of calpain 14 in eosinophilic esophagitis.
NORD Report on Eosinophilic Esophagitis
.Marc E. Rothenberg, MD, PhD
, assisted in preparing this recent report about eosinophilic esophagitis by the National Organization for Rare Disorders (NORD)
. Learn more about his research in the Rothenberg Lab
Allergy-Friendly On-The-Go Snacks
. Carina Venter, PhD, RD, a research associate and dietician at Cincinnati Children's, and Alison Cassin, MS, RD, LD
, give helpful ideas for allergy-friendly, on-the-go snacks.
. Marc E. Rothenberg, MD, PhD
, and Margaret H. Collins, MD
, comment about how big data and file sharing among researchers and pathologists in the Consortium of Eosinophil Gastrointestinal Disease Researchers (CEGIR)
are having a major impact.
Seasonal Allergies: Is it a Cold, Flu or Allergies
. Michelle B. Lierl, MD
, explains how to differentiate cold, flu, and allergies in this article by Your Teen for Parents
Angela Parker, an administrative assistant in our division, accepted the leadership position of Communications Manager with the African American Professional Advisory Committee (AAPAC) here at Cincinnati Children’s. There are currently over 300 members in the group. In this role, she is responsible for sending out information regarding community outreach, lunch and learns, tutoring opportunities and other events.
Marc Rothenberg Receives First Bunning Chair
Cincinnati Children's honored Denise and Dave Bunning for their contributions to the Division of Allergy and Immunology. Cincinnati Children's decided to use this endowment to establish a Chair in Allergy/Immunology that will bear Dave and Denise’s name. Marc E. Rothenberg, MD, PhD, will be the first incumbent of this Chair.
Scientists Identify Potential Marker of EoE Disease Activity. Patricia C. Fulkerson, MD, PhD, assistant professor in the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s, led recent, preliminary research suggesting that eosinophil progenitors in the blood may be a potential marker for disease activity of eosinophilic esophagitis in children. Learn more about her research in the Fulkerson Lab.
Learning to Eat: The Importance of Texture and Food Variety. Carina Venter, PhD, RD, a research associate and dietician at Cincinnati Children's, and Kate Maslin, PhD, RD, an international collaborator, discuss the important of texture and food variety while learning to eat and its potentially life-long effect on food preferences.
Using Cloud Technology in Rare Disease Research: Interview with CEGIR Principal Investigator
NIH Study Finds Protein May Be Responsible for Damage in Eosinophilic Esophagitis
When You're Allergic to Almost Every Food
First-Place DHC Poster
Jeffrey Rymer, predoctoral fellow in the Rothenberg Lab, won the first prize for his poster at the 2016 Annual Scientific Symposium by the Digestive Health Center.
EoGenius Diagnostic Test for Eosinophilic Esophagitis
Miraca Life Sciences now offers the EoGenius test, an RNA expression test, designed to help diagnose eosinophilic esophagitis (EoE). This test is founded in research led by Marc E. Rothenberg, MD, PhD, and Ting Wen, PhD.
Research Achievement Award
Our Division Director, Marc E. Rothenberg, MD, PhD, was recognized for his dedicated efforts with a Research Achievement Award in the Fifth Annual Faculty Awards by Cincinnati Children's. To see Dr. Rothenberg receive the Research Achievement Award, view the Faculty Awards Presentation Video beginning at time point 00:39:05. Learn more about his research in the Rothenberg Lab.
NIDDK Fellowship Award
Jared Travers, an MD, PhD predoctoral fellow in the Rothenberg Lab, was awarded a fellowship grant to study the role of nuclear IL-33 in mucosal inflammation by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Learn more about his research in the Rothenberg Lab.
Improved Scoring System for the Food Allergic Disease Eosinophilic Esophagitis in Children
Researchers have developed and validated a histologic scoring system to objectively analyze pathologic features of eosinophilic esophagitis (EoE), a severe, often painful food allergy that renders children unable to eat a wide variety of foods. This study was led by researchers in the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s Hospital Medical Center.
TOP DOCTOR 2016 List
In Cincinnati magazine, Michelle B. Lierl, MD, and Kimberly A. Risma, MD, PhD, were named in the TOP DOCTOR 2016 list for Allergy and Immunology subspecialty.
Research Innovation Program Award
Simon P. Hogan, PhD, was awarded funding from the Cincinnati Children's Research Innovation/Pilot Funding Program in 2016. This program will support the Hogan Lab in investigating the involvement of antibiotics in antigen sensitization in food allergy. Learn more about his research in the Hogan Lab.