Allergy and Immunology

• American Academy of Allergy Asthma and Immunology (AAAAI)
• American Partnership for Eosinophilic Disorders (APFED)
• ausEE - Australian Eosinophilic Gastrointestinal Disorders Group
• Asociación Española de Esofagitis Eosinofilica (AEDESEO) - Spanish Eosinophilic Esophagitis Group
• Campaign Urging Research for Eosinophilic Disease (CURED)
• Children’s Milk Allergy and Gastrointestinal Coalition U.S. (Children's MAGIC)
• Coalition of Eosinophil Patient Advocacy Groups (C-EOS)
• Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)
• End Allergies Together (EAT)
• Eosinophilic Family Coalition (EFC)
• Families Affected with Eosinophilic Disorders (FABED) - British Eosinophilic Disorders Group
• Food Allergy & Anaphylaxis Connection Team (FAACT)
• Food Allergy Research & Education (FARE)
• Lehedva - Israeli Eosinophilic Esophagitis Group
• Mothers of Children Having Allergies (MOCHA)
• National Center for Advancing Translational Sciences (NCATS)
• National Institute of Allergy and Infectious Diseases (NIAID)
• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Utah Food Allergy Network (UFAN) and the Division of Eosinophilic Support (UFAN-DOES)

DECEMBER 4

How to Talk to Party Hosts About Kids' Nut Allergies

NOVEMBER 14

Lawmakers Propose Council to Help People With Rare Diseases

NOVEMBER 13

Nucala (mepolizumab) is the first treatment to show a significant reduction in flares for patients with Hypereosinophilic Syndrome (HES) 

NOVEMBER 7-10

5th CURED EGID Research Conference and Patient Education Program and "The CURED" Video

OCTOBER

Penicillin Allergy Testing Service set to launch in mid-November

OCTOBER 25

AP-1 activity induced by co-stimulation is rehired for chromatin opening during T cell activation

Marc E. Rothenberg, MD, PhD, shares, "I am pleased to share this research from the Barski Lab. This is an important contribution to the field, defining the epigenetic and transcriptional processes involved in T cell memory. This has direct implications in understanding the immunologic basis of a variety of diseases including allergy." 

OCTOBER 23 

5th CURED Research Conference and Patient Education Program Begins Nov. 7

OCTOBER 5

Efficacy of Dupilumab in Phase 2 Randomized Trial of Adults with Active Eosinophilic Esophagitis

Marc E. Rothenberg, MD, PhD, shares, "These positive data are good news for the patients, as this is a very promising therapy for eosinophilic esophagitis (EoE). This is also good news for the research field, as these clinical results are based on over a decade of research by the Rothenberg Lab, providing the scientific basis of blocking this pathway in EoE and related eosinophilic gastrointestinal disorders (EGIDs)." 

SEPTEMBER 21

Travel Award by Ohio Physiological Society

Rishi Mehta, a student in the Rothenberg Lab, was awarded the AD Instruments Travel Award of the Ohio Physiological Society, which will provide support for him to attend the Experimental Biology 2020 conference. He presented his research in the Rothenberg Lab under the title of "Loss of peptidyl-arginine deiminase 1-mediated citrullination drives esophageal epithelial barrier impairment in allergic inflammation".

AUGUST 5

Phase 2 Randomized, Double-Blind Placebo0Controlled Study in Patients with Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

Marc E. Rothenberg, MD, PhD, shares, "This is exciting news for the eosinophil gastrointestinal community. This early study met the key endpoints and looks promising for the future treatment of eosinophilic gastrointestinal disease. Here at Cincinnati Children's, we are pleased to have contributed to the preclinical research, design and implementation of this drug and study."

MARCH 12

Dr. Rothenberg received the Paul Ehrlich Lectureship Award

Dr. Rothenberg, the Principal Investigator for the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), has been awarded the highest honor bestowed by the International Eosinophil Society for his major contributions to the advancement of our understanding of the eosinophil.

FEBRUARY 19 

Can an Antibody Against IL-13 Be Used to Treat Eosinophilic Esophagitis?

JANUARY 31 

FOX Cincinnati FARE Interview

Sandy Durrani, MD, discusses the increase of allergies on local Cincinnati FOX News in an interview arranged the by Food Allergy Research and Education (FARE).

JANUARY 16

Knopp Biosciences Expands Research Collaboration with Cincinnati Children's to Characterize Effect of Dexpramipexole in Inflammatory Diseases

Through a previous collaboration with Knopp, Patricia Fulkerson, MD, PhD and her team employed an induced pluripotent stem cell (iPSC) culture system to study the ability of dexpramipexole to inhibit the maturation of eosinophil progenitor cells. Looking forward, Dr. Fulkerson and her team will investigate molecular pathways in eosinophil development and attempt to further elucidate the effect of dexpramipexole on those pathways.

JANUARY

Allergy and Immunology Division: Select Research Advances of 2018 Video

Through our sustained commitment to research and clinical excellence for allergic and immunologic conditions, we will continue to change the outcome together. This slideshow highlights notable scientific advances made by The Division of Allergy and Immunology at Cincinnati Children’s in 2018. Our research has advanced the understanding, diagnosis, prevention, and treatment of many rare and common allergic and immunologic diseases.

JANUARY

Zuckerman Scholar

Netali Morgenstern-Ben Baruch is a 2018/2019 Zuckerman Israeli Postdoctoral Scholar of the Zuckerman Scholars Program and is investigating an inhibitory receptor, ILT-2, to learn about its role in the type 2 inflammatory disease Eosinophilic esophagitis (EoE).

NOVEMBER

Marc Rothenberg, MD, PhD Recognized as a Highly Cited Researcher for 2018

NOVEMBER 22

New Drug Could Be Game-changer For Kids With Severe Peanut Allergies

NOVEMBER 18

Landmark PALISADE Trial of AR101 Published in New England Journal of Medicine - read the open-access journal article

NOVEMBER 9

Anti-IL-13 Phase 2 Trial for Eosinophilic Esophagitis

OCTOBER

Proyecto EoE y Ausencia de Proteina SPINK7:Entrevista al Investigador Principal - see the October issue (pages 8-9) of the AEDESEO newsletter for an interview with Marc Rothenberg, MD, PhD

OCTOBER 24

Scientists Discover Why So Many Children Born With a Defective Esophagus Develop Severe Food Allergies

OCTOBER 22

DBV Technologies Announces Submission of Biologics License Application for Viaskin Peanut to the U.S. Food and Drug Administration

OCTOBER 18

A revolutionary treatment for allergies to peanuts and other foods is going mainstream--but do the benefits outweigh the risks?

OCTOBER 12

Thomas J. Fischer Endowed Education Fund

SEPTEMBER 7

Durrani Spem Facit

Our clinical team members are dedicated to excellence in patient care. For Sandy Durrani, MD, this was recently recognized by a grateful patient family naming a star “Durrani Spem Facit”, which loosely translates from Latin to mean ‘hope maker’. We are so proud of Sandy and all of our stellar team members for changing the outcome together.

JULY 3

Eosinophilic Esophagitis Video: What is EoE?

JUNE 6

Study Finds Absence of Key Protein, SPINK7, May Drive EoE: Replacement Therapy Reversed Effects in Tissue Experiments

MAY 2

Discovery Could Lead to Personalized Medical Therapies for Emerging New Food Allergy Disorder

JANUARY 3

Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers
This is a fantastic summary of the formation of CEGIR, the Consortium of Eosinophilic Gastrointestinal Disease Researchers, the first large-scale collaboration between key stakeholders in the field of eosinophilic gastrointestinal disorders, including researchers, patients and the key funding agency, the NIH. CEGIR is dedicated to improving the lives of individuals with eosinophilic gastrointestinal disorders through innovative research, clinical expertise and education via collaborations between scientists, health care providers, patients, and professional organizations.

DECEMBER 5

Tips for Hosting a Food-Allergy-Friendly Holiday Party

NOVEMBER 16

Cincinnati Children's Research Paves Way For Newly Approved Asthma Drug

NOVEMBER 8

A Family Journey
The CURED Conference brought together patient families, physicians, and researchers from across the globe to learn from each other. One of the most moving and memorable presentations was a patient perspective from Kara Root, whose story inspires us here at Cincinnati Children’s as well those across the eosinophilic gastrointestinal disorder (EGID) community. You can read more about Kara and her family’s journey on her blog.

OCTOBER 23

Celebrating 140 Collective Years of Service of Allergy and Immunology at Cincinnati Children's
The Division of Allergy and Immunology is celebrating a unique year as six division faculty observe their 10-, 20-, 30-, and 40-year Cincinnati Children's service anniversaries! Their sustained contributions at multiple levels and their influence on past and future generations put the division in a strong position. Here, they offer insight into the changes they have been part of and where the division is going.

OCTOBER 10

Environmental Factors Could Adjust Risk of Eosinophilic Esophagitis in People with Particular Gene Variants

AUGUST 30

Handy Checklist: Going to College with an Eosinophilic Gastrointestinal Disorder

AUGUST 30

Pushing for Progress in a Rare Eosinophilic Condition: Eosinophilic Gastritis

JULY 17

What's the right time to use an EpiPen?
Amal H. Assa'ad, MD comments about administering epinephrine auto-injectors for anaphylaxis in this news video.

JULY 13

Family Fights For Formula Coverage Despite it Being Illinois Law
In this NCB Chicago news segment, Marc E. Rothenberg, MD, PhD and professional and family colleagues comment about insurance coverage for medical formulas.

MAY 22

FARE Patient Registry
The FARE Patient Registry launched on May 22, 2017 and is a patient-powered research registry, created with collaboration by FARE’s Medical Advisory Board, members of the Outcomes Research Advisory Board and AltaVoice, a leading registry platform and expert in the field of online protection and privacy.

MAY 17

FDA-approved drug helps treat rare immunologic disease, study finds
The NIH reports on a phase 3 clinical trail that they co-funded and that tested mepolizumab (humanized antibody against IL-5) as an alternative treatment for an eosinophilic syndrome, eosinophilic granulomatosis with polyangiitis (EGPA; previously known as Churg-Strauss syndrome).

MARCH 30

2017 FARE Research Retreat: Q&A with Dr. Simon Hogan
Simon P. Hogan, PhD, received a FARE Investigator in Food Allergy Award in 2015. With this support, the Hogan Lab is investigating how proteins released at the start of an allergic response can cause blood vessels to leak during life-threatening anaphylaxis. Understanding the chain of chemical events that leads to anaphylactic shock is a key step in devising strategies to prevent severe food allergy symptoms. Hogan presented at the FARE 2017 Research Retreat and explains his work in this Q&A on the FARE blog.

MARCH 28

Poster of Distinction, Nutrition Research Day
Mark Rochman, PhD, and Carina Venter, PhD, RN, and their students, Rachel Ernst and Tarah Wagner won the Poster of Distinction at the Nutrition Research Day Poster Session at Cincinnati Children's for their work on peanut protein levels.Ernst and Wagner went on to take first place in the Agriculture / Food Science category at their high school's capstone competition on April 28.

MARCH 16

K08 Award
Andrew W. Lindsley, MD, PhD was awarded a K08 from the National Institute of Allergy and Infectious Diseases (NIAID). This NIH clinical scientist career development award will support the Lindsley Lab in investigating how the sphingolipid ORMDL3 regulates dendritic cells in asthma.

MARCH 15

NIH R01 and DHC Awards
Patricia C. Fulkerson, MD, PhD was awarded an R01 from National Institute of Allergy and Infectious Diseases (NIAID). This R01 will support the Fulkerson Lab in investigating the role of the transcription factor Aiolos in eosinophilic asthma. Learn more about her research in the Fulkerson Lab.

MARCH 3-6

2017 AAAAI Annual Meeting Awards
For the 2017 American Academy of Asthma, Allergy & Immunology (AAAAI) Annual Meeting, our Cincinnati Children’s/University of Cincinnati College of Medicine colleagues presented over 50 presentations, which is an impressive number. This underscores the collective impact that Cincinnati Children’s/University of Cincinnati College of Medicine is having in our field. Dr. Justin Wheeler was the recipient for the award for the 2017 AAAAI/APFED Best Oral Abstract on eosinophilic gastrointestinal diseases by a fellow-in-training. Amnah Yamani, a predoctoral student in the Hogan Lab, was selected to be in the featured poster session. Amal H. Assa’ad, MD, was selected to give the first Leonard Bernstein Lectureship. This lectureship was established in memory of our legendary Dr. Leonard Bernstein, who was a pioneer in the allergy field, founder of the allergy discipline in Cincinnati and a wonderful mentor and contributor to our program. The lectureship was sponsored by donations from the Bernstein Family and Dr. Bernstein’s past trainees and colleagues.

MARCH 5

FADDA Interest Section
Amal H. Assa’ad, MD, was elected by her peers to serve as the Secretary of the AAAAI’s Food allergy, anaphylaxis, dermatology and drug Allergy (FADDA) Interest Section from March 5, 2017 until March 2019. After the 2019 AAAAI Annual Meeting and until the 2021 Annual Meeting, she will serve in the role as the Vice Chair of the interest section, and then from 2021 until 2023, she will serve in the role of Chair of FADDA.

FEBRUARY 17

Clinical Care Award
Michelle B. Lierl, MD, was selected by The Faculty Awards Committee at Cincinnati Children's for the Clinical Care Award. This is a well-deserved honor for Dr. Lierl, who is now in her 30th anniversary year at Cincinnati Children's. In addition to her great clinical service, Dr. Lierl researches fungal allergens in the Lierl Lab and has created a fungal spore photo website.

JANUARY 17

2016 Division Research Advances Video
We invite you to watch a short video detailing a few of the Division of Allergy and Immunology’s Research Advances of 2016. Through our sustained commitment to research and clinical excellence for allergic and immunologic conditions, we will continue to change the outcome together.

JANUARY 3

CURED Foundation donates for Eosinophilic Disorder Treatment and Research
The Campaign Urging Research for Eosinophilic Disease (CURED), a not-for-profit foundation dedicated to those suffering from eosinophilic disorders, has donated $200,000 to the Cincinnati Center for Eosinophilic Disorders (CCED), based at Cincinnati Children’s Hospital Medical Center. The CURED Foundation works extensively in supporting families and raising funds for research. One-hundred percent of funds raised by the CURED Foundation go to research for eosinophilic disorders. To date, CURED has contributed over 4 million dollars to research.

JANUARY

2017 NIAID Addendum Guidelines for Preventing Peanut Allergy
In 2015, findings from a landmark NIAID-funded clinical trial called the Learning Early About Peanut (LEAP) study showed that introducing peanut-containing foods to infants at high risk for developing peanut allergy was safe and led to an 81% relative reduction in the subsequent development of peanut allergy. Due to the strength of these results, NIAID established a coordinating committee that convened an expert panel to update the 2010 Guidelines to specifically address the prevention of peanut allergy. Amal H. Assa'ad, MD, and Carina Venter, PhD, RD, contributed to the Addendum Guidelines for the Prevention of Peanut Allergy in the United States that were published in the January 2017 issue of Annals of Allergy and Immunology, along with a guest editorial by Amal H. Assa'ad, MD.

JANUARY

2017 AAAAI Distinguished Service Award
Well-deserved congratulations go to Kimberly A. Risma, MD, PhD, for being selected for the 2017 Distinguished Service Award of the American Academy of Asthma, Allergy & Immunology (AAAAI) for her leadership with the Chrysalis Project. The Chrysalis Project is a program for medical students and internal medicine and/or pediatric residents that provides them the opportunity to explore a career in allergy/immunology. It is housed within the AAAAI Annual Meeting and includes pairing the Chrysalis mentee with a fellow-in-training mentor, didactic lectures with allergy/immunology faculty, career option presentations, and free conference registration and access to the leading knowledge in the hundreds of AAAAI meeting sessions, workshops, symposia, seminars, and oral abstracts. Dr. Risma has helped to propel this program to become a jewel of our society and is thus greatly impacting our field and its future. Through her efforts, she has established a ‘pipeline’ of strong physicians in our field. In 2010, Dr. Risma was nominated by the Board of AAAAI to assume the co-Chair position of the Chrysalis Program Project after a pause in the program’s funding. She has subsequently worked tirelessly on the Chrysalis Project with current AAAAI president, Dr. Tom Fleisher between 2010-15 and former AAAAI president, Dr. Wesley Burks in 2015-17. Under her leadership, the program has expanded from 20 to 50 attendees per year. The Chrysalis Project has been extraordinarily well received as is evident from the growing number of highly qualified applicants and attendees, the positive reviews, and the growing number of fellowship applicants who credit the Chrysalis Project.

DECEMBER 13

Cincinnati Children’s was recently issued US Patent 9517238 B2 for the work of the inventors Marc E. Rothenberg and Mark Rochman. The invention provides methods of treating allergic inflammatory conditions using an anti-neurotrophin tyrosine kinase receptor 1 (NTRK1)-based therapeutic agent and related compositions and methods. The underlying research for this patent was conducted in the Rothenberg Lab.

DECEMBER 13

Hosting a Food-Allergy-Friendly Holiday Party

NOVEMBER 30

FARE Joins with National Academies of Sciences, Engineering and Medicine in Call for Sweeping Changes to Improve Health, Quality of Life of Individuals With Food Allergies
We would like to mention that this vital work was made possible by so many contributors, including our colleague Carina Venter, PhD, RD, who served as a reviewer and contributor to this 500-page report on food allergy.

NOVEMBER

Trustee Grant Award
Ting Wen, PhD was awarded a Trustee Grant Award by Cincinnati Children’s to support his research.

NOVEMBER 11

Allergy Guideline Updating Efforts
We are proud of all the dedicated efforts made to move the guidelines for allergen introduction forward. Our colleague Amal H. Assa’ad, MD, comments in this NPR update, and our colleague Carina Venter, PhD, RD, is involved as a member of the scientific panel who are updating the guidelines that will be published in January on the National Institute of Allergy and Infectious Diseases (NIAID) website. Listen to or read the NPR segment (by Patti Neighmond). Read the Reuter's article (by Rob Goodier). Read Dr. Venter's JACI editorial about the LEAP study findings about early allergen consumption.

September 23

5 Tips for Packing a Well-Rounded Nut-free Lunch

AUGUST 29

LEAP Study Editorial
The Journal of Allergy and Clinical Immunology has included the LEAP (Learning Early About Peanut) nutrition study for its readership. Our colleague Carina Venter, PhD, RD, co-authored an editorial about the study findings about early allergen consumption.

AUGUST

CURED Foundation Donates for Eosinophilic Disorder Treatment and Research
The Campaign Urging Research for Eosinophilic Disease (CURED), a not-for-profit foundation dedicated to those suffering from eosinophilic disorders, has donated $100,000 to the Cincinnati Center for Eosinophilic Disorders (CCED), based at Cincinnati Children’s Hospital Medical Center. The CURED Foundation works extensively in supporting families and raising funds for research. One-hundred percent of funds raised by the CURED Foundation go to research for eosinophilic disorders. To date, CURED has contributed over 4 million dollars to research.

August

UC Summer Research Prepares Students for STEMM Careers
Two hundred college and high school students from the across the country participated in the 2016 Summer Undergraduate Research Fellowship (SURF) Capstone Poster Sessions sponsored by several programs at the UC College of Medicine and Cincinnati Children’s Hospital Medical Center as part of the SURF initiative, designed to provide rich research internship experiences for college students and high school seniors. All student winners were recognized during an awards ceremony. Marc Rothenberg, MD, PhD, Director of both the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s, gave the ceremony’s keynote speech. At its conclusion, he eulogized Olivia Erhardt, a 2015 SURF participant and Columbia University student who performed summer research in his laboratory at Cincinnati Children’s. Erhardt tragically lost her life in a bus accident during a medical mission trip to Honduras in January 2016.

July

Infants and Solid Food, an Introductory Course. Carina Venter, PhD, RD, a research associate and dietician at Cincinnati Children's, discusses the transition from formula to solid food in infancy while navigating potential food allergies.

AAAAI Foundation & Dr. Donald Y.M. Leung/JACI Editors Faculty Development Award
Andrew W. Lindsley, MD, PhD, was interviewed about his recent award, the AAAAI Foundation and Dr. Donald Y.M. Leung/JACI Editors Faculty Development Award for his project investigating how ORMDL3 enhances macrophage function in asthma pathogenesis.

July 22

Darrel E. Goll Award for Scholarly Publication
Our collaborator, Leah C. Kottyan, PhD, received the Darrel E. Goll Award at the FASEB Biology of Calpains in Health and Disease Conference. This award recognizes the most outstanding publication in the field of calpains in the past three years, and we are proud for members of the Rothenberg Lab to have contributed to this outstanding work over the years. Their recent calpain publications include explore the tissue specificity and contribution of calpain 14 in eosinophilic esophagitis.

July 21

NORD Report on Eosinophilic Esophagitis.Marc E. Rothenberg, MD, PhD, assisted in preparing this recent report about eosinophilic esophagitis by the National Organization for Rare Disorders (NORD). Learn more about his research in the Rothenberg Lab.

July 12

Allergy-Friendly On-The-Go Snacks. Carina Venter, PhD, RD, a research associate and dietician at Cincinnati Children's, and Alison Cassin, MS, RD, LD, give helpful ideas for allergy-friendly, on-the-go snacks.

July 9

Harnessing the Power of Big Data. Marc E. Rothenberg, MD, PhD, and Margaret H. Collins, MD, comment about how big data and file sharing among researchers and pathologists in the Consortium of Eosinophil Gastrointestinal Disease Researchers (CEGIR) are having a major impact.

July 7

Seasonal Allergies: Is it a Cold, Flu or Allergies. Michelle B. Lierl, MD, explains how to differentiate cold, flu, and allergies in this article by Your Teen for Parents.

June

Angela Parker, an administrative assistant in our division, accepted the leadership position of Communications Manager with the African American Professional Advisory Committee (AAPAC) here at Cincinnati Children’s. There are currently over 300 members in the group. In this role, she is responsible for sending out information regarding community outreach, lunch and learns, tutoring opportunities and other events.

May 17

Marc Rothenberg Receives First Bunning Chair
Cincinnati Children's honored Denise and Dave Bunning for their contributions to the Division of Allergy and Immunology. Cincinnati Children's decided to use this endowment to establish a Chair in Allergy/Immunology that will bear Dave and Denise’s name. Marc E. Rothenberg, MD, PhD, will be the first incumbent of this Chair.

May 16

Scientists Identify Potential Marker of EoE Disease Activity. Patricia C. Fulkerson, MD, PhD, assistant professor in the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s, led recent, preliminary research suggesting that eosinophil progenitors in the blood may be a potential marker for disease activity of eosinophilic esophagitis in children. Learn more about her research in the Fulkerson Lab.

May 13

Learning to Eat: The Importance of Texture and Food Variety. Carina Venter, PhD, RD, a research associate and dietician at Cincinnati Children's, and Kate Maslin, PhD, RD, an international collaborator, discuss the important of texture and food variety while learning to eat and its potentially life-long effect on food preferences.

April 15

Using Cloud Technology in Rare Disease Research: Interview with CEGIR Principal Investigator

April 7

NIH Study Finds Protein May Be Responsible for Damage in Eosinophilic Esophagitis

March 9

When You're Allergic to Almost Every Food

March 1

First-Place DHC Poster
Jeffrey Rymer, predoctoral fellow in the Rothenberg Lab, won the first prize for his poster at the 2016 Annual Scientific Symposium by the Digestive Health Center.

March 1

EoGenius Diagnostic Test for Eosinophilic Esophagitis
Miraca Life Sciences now offers the EoGenius test, an RNA expression test, designed to help diagnose eosinophilic esophagitis (EoE). This test is founded in research led by Marc E. Rothenberg, MD, PhD, and Ting Wen, PhD.

February 19

Research Achievement Award

Our Division Director, Marc E. Rothenberg, MD, PhD, was recognized for his dedicated efforts with a Research Achievement Award in the Fifth Annual Faculty Awards by Cincinnati Children's. To see Dr. Rothenberg receive the Research Achievement Award, view the Faculty Awards Presentation Video beginning at time point 00:39:05. Learn more about his research in the Rothenberg Lab.

February 12

NIDDK Fellowship Award

Jared Travers, an MD, PhD predoctoral fellow in the Rothenberg Lab, was awarded a fellowship grant to study the role of nuclear IL-33 in mucosal inflammation by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Learn more about his research in the Rothenberg Lab.

February 9

Improved Scoring System for the Food Allergic Disease Eosinophilic Esophagitis in Children
Researchers have developed and validated a histologic scoring system to objectively analyze pathologic features of eosinophilic esophagitis (EoE), a severe, often painful food allergy that renders children unable to eat a wide variety of foods. This study was led by researchers in the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s Hospital Medical Center.

January 1

TOP DOCTOR 2016 List
In Cincinnati magazine, Michelle B. Lierl, MD, and Kimberly A. Risma, MD, PhD, were named in the TOP DOCTOR 2016 list for Allergy and Immunology subspecialty.

January

Research Innovation Program Award
Simon P. Hogan, PhD, was awarded funding from the Cincinnati Children's Research Innovation/Pilot Funding Program in 2016. This program will support the Hogan Lab in investigating the involvement of antibiotics in antigen sensitization in food allergy. Learn more about his research in the Hogan Lab.

December

Eosinophil Researcher Honored as Schmidlapp Woman Scholar
Patricia C. Fulkerson, MD, PhD, assistant professor in the Division of Allergy and Immunology and the Cincinnati Center for Eosinophilic Disorders at Cincinnati Children’s, has been selected as a 2015 Schmidlapp Woman Scholar by the the Fifth Third Bank / Charlotte R. Schmidlapp Women Scholars Program. Learn more about her research in the Fulkerson Lab.

December

Cincinnati Golfers for Charity
Thank you to the Cincinnati Golfers for Charity for supporting our clinical and research efforts in the Cincinnati Center for Eosinophilic Disorders.

November

The Untold Story of a New Asthma Drug
The FDA approved the drug mepolizumab on November 4th to help treat severe asthma, which was an achievement grounded in many years of research and testing by innumerable physicians and scientists, including those at Cincinnati Children's, such as Marc Rothenberg, MD, PhD. Learn more about his research in the Rothenberg Lab.

October 5

Noah Kennedy: Colerain Football's Mightiest Team Member

September 30

Department of Defense Award

Yui-Hsi Wang, PhD, was awarded a FY14 Peer Reviewed Medical Research Program (PRMRP) Investigator-Initiated Research Award from the United States Department of Defense for his project "IL-9-Producing Mast Cell Precursors and Food Allergy".

September 30

DP2 Award

Artem Barski, PhD, was awarded a DP2 Award by the National Institutes of Health for his project "Direct Epigenetic Reprogramming of T Cells". Learn more about his research in the Barski Lab.

September 23

New Cell Type May Help Explain Why Some People Have Dangerous Food Allergies

Yui-Hsi Wang, PhD, and his colleagues report their discovery of a new cell type that appears to drive life-threatening food allergies and may help explain why some people get severe allergic reactions and others do not.

September 1

NIAID R01
Marc Rothenberg, MD, PhD, was awarded an R01 by the National Institute of Allergy and Infectious Diseases (NIAID) for his project "Genetic and Immunological Dissection of Eosinophilic Esophagitis". Learn more about his research in the Rothenberg Lab.

August 7

Most Outstanding Translational Research Achievement between 2010-2015

At the faculty "State of the Union" address, Marc Rothenberg, MD, PhD, was recognized with the "Most Outstanding Translational Research Achievement between 2010-2015" for his work towards the Nature Genetics publication," Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease” published in Nat Genet. 2014 Aug;46(8):895-900." Learn more about his research in the Rothenberg Lab.

August

EoE in Evolution: The Search Continues for Better Treatments and Diagnostics
Marc Rothenberg, MD, PhD, director of the division and the Cincinnati Center for Eosinophilic Disorders comments in this article about the search for better treatment and diagnostics for eosinophilic esophagitis (EoE). Learn more about his research in the Rothenberg Lab.

July

Trustee Award

Artem Barski, PhD, was awarded a Trustee Award by Cincinnati Children's for his project "Epigenetic Suppression of IL4 Expression in T Cells". Learn more about his research in the Barski Lab.

JUNE 29

Cincinnati Children's becomes Center of Excellence and an inaugural member of the Food Allergy Research & Education (FARE) Clinical Network.

JUNE

Digestive Health Center Pilot and Feasibility Award

Ting Wen, PhD, was awarded a Digestive Health Center Pilot and Feasibility Award for his project "Analysis and Function of Esophageal Lymphocytes in Eosinophilic Esophagitis".

June 4

Parent-reported Symptoms Gauge Pathogenic Features of the Food Allergic Disease Eosinophilic Esophagitis in Children

June

Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High-Risk Infants

May

NIAID Award

Divisional collaborators Simon P. Hogan, PhD, and Yui-Hsi Wang, PhD, and national collaborator Rodney Newberry, MD, (Washington University in St. Louis) were awarded a multi-principal investigator R01 grant from the National Institute of Allergy and Infectious Diseases (NIAID) for their project "Food Allergy and Goblet Cell Antigen Passages". Learn more about research in the Hogan Lab.

May

CURED Foundation Donates $100,000 For Eosinophilic Disorder Treatment and Research

May

AAI Careers in Immunology Fellowship

Artem Barski, PhD, and Masahi Yukawa were awarded a Careers in Immunology Fellowship award by the American Association of Immunologists (AAI). Learn more about their research in the Barski Lab.

April

Cincinnati Children's Moms Expand Camp for Kids with Eosinophilic Disorders

April

Integrating Grantseeking and Fundraising

Division Business Director, Kevin Titus, MBA, was recently asked for his perspective on the important of integrated strategic planning for the white paper Integrating Grantseeking into Hospital Foundation Fundraising Plans published by Hanover Research.

March

APFED HOPE Pilot Grant

Ting Wen, PhD, was awarded a 2015 APFED HOPE Pilot Grant for his project "Defining Esophageal Lymphocyte Phenotype and Function in Eosinophilic Esophagitis" from the American Partnership for Eosinophilic Disorders (APFED). This award is designed to support the initiation of research that will be the basis of a larger research project within the subspecialty of eosinophilic disorders.

March

Cincinnati Children's T1 Innovative Core Grant

Artem Barski, PhD, and Andrey V. Kartashov, MS, were awarded a T1 Innovative Core Grant by Cincinnati Children's for the Wardrobe Server. Wardrobe is a software package for storing and analyzing chromatin immunoprecipiation sequencing, RNA sequencing, and similar datasets. It was collaboratively generated by Barski and Kartashov. Learn more about their research in the Barski Lab.

March

FARE Award

Simon P. Hogan, PhD, was awarded a 2015 FARE Investigator in Food Allergy Award. This Mid-Career Investigator Award from Food Allergy Research & Education (FARE) will support Hogan in identifying the key proteins and cells that cause the blood vessel fluid leak leading to severe anaphylaxis triggered by foods. Learn more about his research in the Hogan Lab.

March

First-Place Graduate Student Research Forum Poster

Congratulations to Rothenberg Lab member and predoctoral fellow Rahul D'Mello for winning First Place at the 2015 Graduate Student Research Forum poster competition at the University of Cincinnati College of Medicine.

March

ASCI Young Physician-Scientist Award

Patricia C. Fulkerson, MD, PhD, was awarded a 2015 Young Physician-Scientist Award by the American Society for Clinical Investigation. The ASCI Council Young Physician-Scientist Awards recognize early-stage physician-scientists who are early in their first faculty appointment and have made notable achievements in their research. This award provides an honorarium for her to present her research at the ASCI/ American Association of Physicians (AAP) Joint Meeting. Learn more about her research in the Fulkerson Lab.

March 3

First-Place DHC Poster

Nurit Azouz, PhD, a research fellow in the Rothenberg Lab, won the first prize for her poster at the 2015 Annual Scientific Symposium by the Digestive Health Center.

February 28

New Patient Contact Registry for Rare Eosinophilic Gastrointestinal Diseases

To coincide with Rare Disease Day® 2015, the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) launched a patient contact registry for individuals with eosinophilic gastrointestinal diseases (EGID), a group of rare diseases. Marc Rothenberg, MD, PhD, is the principal investigator of the National Institutes of Health grant that funds the CEGIR (U54 AI117804).

February 25

MicroRNA Potential Biomarker for Esophagitis

Faculty member Ting Wen, PhD, recently commented in an article discussing microRNA as potential biomarkers for esophagitis.

February

Mentoring Achievement Award

Our division's Director of Research, Simon P. Hogan, PhD, was recognized for his dedicated efforts with the Mentoring Achievement Award in the Fourth Annual Faculty Awards by Cincinnati Children's.

Joseph E. Ghory, M.D.

1915-1988

Dr. Joseph Ghory was born and raised in Cincinnati, Ohio. He received his M.D. from the Ohio State University College of Medicine in 1939. After completing a pediatric residency at the Children's Hospital in Cincinnati, he practiced general pediatrics in Cincinnati for 17 years.

He was devoted to teaching and was instrumental in establishing the pediatric residency training program at Good Samaritan Hospital, where he served as the first director of pediatric education. He was elected president of the Cincinnati Pediatric Society, the Children’s Hospital Medical Staff and the Academy of Medicine of Cincinnati. Impressed by the large number of children with allergic diseases, he sought additional training in allergy and became the first board-certified pediatric allergist in Cincinnati in 1960. Together with Dr. Leonard Bernstein, Dr. Ghory established the Allergy Fellowship at the University of Cincinnati and the Children’s Hospital.

Dr. Ghory’s special interest and vision was the long-term care and rehabilitation of children with intractable asthma, using a community approach with involvement of the family and a limited hospital stay. He thus became director of the Convalescent Hospital for Children in Cincinnati, organized and presided over the national Association of Convalescent Homes and Hospitals for Asthmatic Children and was chairman of the Rehabilitation Committee of the American Academy of Allergy and Immunology.

Dr. Ghory’s greatest pride was his family, and his legacy lives on in two of his daughters, Ann Ghory, M.D. and Patricia Ghory, M.D., who are practicing allergists in the Cincinnati area, and now in three of his grandchildren, who are now our young practicing and future allergists. 

2010-2019

2019 – William W. Busse

2018 – Seema Aceves

2017 – Elizabeth Phillips

2016 – Carina Venter

2015 – Kara Shah

2014 – Linda Cox

2013 – Kimberly Risma

2012 – David Fleischer

2011 – Amal Assa’ad

2000-2009

2009 – Marc Rothenberg

2008 – Scott Sicherer

2007 – Carolyn Kercsmar

2006 – Jim Gern

2005 – Sally Wenzel

2004 – Anne-Marie Irani

2003 – Donald Leung

2002 – Fernando Martinez

2001 – Marianne Frieri

2000 – Wesley Burks

1991-1999

1999 – Alan Kaplan

1998 – Bruce Bochner

1997 – Robert Lemanske

1996 – Peter Creticos

1995 – Michael Blais

1994 – Paul Greenberger

1993 – Elliot Ellis

1992 – Louise Marker

1991 – Sami Bahna