Allergy and Immunology

Publications

Aceves, SS; Manresa, MC; Dellon, ES; Rieder, F; Collins, MH; Lucendo, AJ; Rothenberg, ME. Tissue remodeling in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2026; 158(2):342-355.

Aoki, M; Yamada, S; Kimura, T; Yamaguchi, M; Tanaka, Y; Matsuyama, K; Osonoi, K; Umetsu, S; Sogo, T; Shoda, T. Changing landscape of pediatric eosinophilic gastrointestinal diseases highlighted by updated consensus criteria. Pediatric Allergy and Immunology. 2026; 37(8):e70439.

Arora, N; Risma, K; Kwan, M; Winslow, A. Penicillin Allergy Decision & Mobile Empowerment (PADME)-Ideation and design of a novel delabeling program for children. Journal of Allergy and Clinical Immunology: In Practice. 2026; 14(5):1192-1195.e3.

Asna Ashari, K; Macrae, R; Hoytema Van Konijnenburg, DP; Platt, CD; Ashoor, M; See, AP; Kielian, A; Danehy, A; Kumar, R; James, E; Risma, K; Ombrello, MJ; Dedeoglu, F; Andzelm, MM. Neurological manifestations and vasculopathy in PLCG2–associated antibody deficiency and immune dysregulation (APLAID): a case series. Pediatric Rheumatology. 2026.

Azouz, NP; Klingler, AM; Beach, SS; Rossey, K; Rochman, M; Paul, M; Caldwell, JM; Brusilovsky, M; Dwyer, AT; Chen, X; Miller, D; Forney, C; Kottyan, LC; Weirauch, MT; Rothenberg, ME. IL-13 and calpain-14 suppress the expression of SPINK7 by regulating OVOL1 in eosinophilic esophagitis. JCI Insight. 2026; 11(12).

Bonfield, M; Gray, J; Ramiriqui, A; Stevens, J; Pandey, U; Canaday, L; Feldman, HA; Zacharias, WJ; Kottyan, L; Waggoner, SN; Deshmukh, H; Steinmeyer, S. Single cell atlas of lung-resident innate lymphoid cells shows impact of age and dysbiosis on epigenetic and transcriptomic programming. Mucosal Immunology. 2026; 19(2):1835-1847.

Caldwell, JM; Ballaban, AY; Li, J; Maddux, R; Harris, S; Dellon, ES; Rothenberg, ME. Cendakimab (anti-IL-13) administration improves esophageal gene expression in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2026; 157(1):118-130.e7.

Cay, M; Onal, C; Herbert, L; Engel, M; Sharma, H; Mahboobeh, M; Assa'ad, A; Moy, J; Bilaver, L; Gupta, R; Warren, C. Psychosocial Burden of Multiple IgE-Mediated Food Allergies in Pediatric Patients and Caregivers in the FORWARD Study. Nutrients. 2026; 18(11).

Chang, HR; Bannon, M; Opper, C; Slavotinek, A; Hijazi, G; Widmeyer, KM; Kellner, ES; Iqneibi, M; Bayart, C; Marathe, KS; Bridges, C. Neonatal Inflammatory Skin and Bowel Disease 1 (NISBD1): A Case of ADAM17 Homozygous Mutation. Pediatric Dermatology. 2026; 43(2):378-381.

Chang, WC; Martin, LJ; Satish, L; Williams, L; Hammonds, M; Jenkins, S; Osswald, G; Caldwell, J; Rothenberg, ME; Khurana Hershey, GK; Biagini, JM. Longitudinal enrichment of eosinophilic esophagitis in children with AD: The MPAACH cohort. Journal of Allergy and Clinical Immunology. 2026; 157(4):999-1001.

Chehade, M; Meyers, S; Mccright-Gill, T; Gifford, R; Sahin, M; Shy, ME; Manion, M; Campbell, D; Rothenberg, ME; Macaluso, M. Collaboration as a Catalyst for Advancing Rare Disease Research: The Experience of the Rare Diseases Clinical Research Network. Clinical and Translational Science. 2026; 19(6):e70585.

Covington, C; Du Toit, G; Spergel, J; Rothenberg, ME. Eosinophilic Gastrointestinal Disorders Prevention: Insights from Early Life Influences and Atopic Conditions. Journal of Allergy and Clinical Immunology: In Practice. 2026; 14(8):1751-1752.

Devonshire, AL; Magier, AZ; Wilson, BE; Rosenberg, C; Winslow, A; Risma, KA; Abonia, JP; Sherenian, MG; Assa'ad, AH; Andorf, S; Schwartz, JT. Peanut oral immunotherapy at a single academic medical center using a volume-based approach with store-purchased peanut products. Journal of Allergy and Clinical Immunology: Global. 2026; 5(3):100652.

Dexheimer, PJ; Hass, MR; Edsall, LE; Diouf, AA; Jones, SH; Donmez, O; Yin, C; Dunn, KA; Forney, C; Hesse, HK; Lawson, LP; Hughes, TR; Kottyan, LC; Weirauch, MT. Systematic investigation reveals extensive Epstein-Barr virus transcriptional regulation of the human genome. Cell Genomics. 2026; 6(8):101303.

Dileep, A; Bilaver, LA; Warren, C; Onal, C; Abellard, A; Fekry, B; Sharma, HP; Assa'ad, AH; Moy, JN; Nimmagadda, S; Jiang, J; Newmark, PJ; Gupta, RS; Mahdavinia, M. Factors Associated with Outgrowing Food Allergies: Insights from a Large Food Allergy Cohort. Annals of Allergy, Asthma and Immunology. 2026.

Dribin, TE; Sampson, HA; Schnadower, D; Anagnostou, A; Fox, AT; Golden, DBK; Michelson, KA; Shaker, MS; Wang, J; Alqurashi, W; Eftekhari, S; Jaffee, H; Carver, M; Camargo, CA. Non-injectable versus injectable epinephrine treatment thresholds for acute allergic reactions in the community. Journal of Allergy and Clinical Immunology: In Practice. 2026; 14(4):976-980.

Dribin, TE; Sampson, HA; Anagnostou, A; Camargo, CA; Fox, AT; Golden, DBK; Michelson, KA; Shaker, MS; Wang, J; Alqurashi, W; Douglas, L; Nickels, C; Moore, RA; Schnadower, D. Epinephrine and emergency medical services activation recommendations during acute allergic reactions in community settings: International consensus report. Journal of Allergy and Clinical Immunology. 2026; 157(2):429-441.

Forrest, CB; Koenigsberg, LJ; Schwebel, DC; Bassuk, AG; Dennery, PA; Flores, G; Murray, KO; Perera, U; Rivara, FP; Kottyan, LC. Recent trends and structural patterns in NIH pediatric research funding, 2015-2024. Pediatric Research. 2026.

Gill, KK; Moore, C; Nwogu, O; Kroner, JW; Chang, W-C; Burkle, J; Virolainen, SJ; Stevens, ML; Baatyrbek, A; Miraldi, ER; Martin, LJ; Andorf, S; Khurana Hershey, GK; Roskin, KM. B-Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization. Allergy. European Journal of Allergy and Clinical Immunology. 2026; 81(2):513-523.

Gonsalves, NP; Dellon, ES; Kliewer, KL; Shoda, T; Yearout, R; Aceves, SS; Arva, NC; Besse, JA; Caldwell, JM; Chehade, M; Deniz, Y; Furuta, GT; Martin, LJ; Rothenberg, ME. Dupilumab versus placebo in adults and adolescents with eosinophilic gastritis (DEGAS): a double-blind, placebo-controlled, phase 2, multicentre, randomised controlled trial. The Lancet Gastroenterology and Hepatology. 2026; 11(8):672-688.

Hamed, M; Naderian, M; Bangash, H; Hernandez, V; Shaibi, GQ; Arslan, M; Saadatagah, S; Sherafati, A; Miller, A; Kamzabek, A; Caraballo, PJ; Freimuth, R; Sharp, RR; Kullo, IJ. Implementing a Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease in a Diverse Cohort. Genetics in Medicine. 2026; 102662.

Hanks, S; Suckiel, S; Golfinopoulos, L; Marathe, P; Odgis, J; Bonini, K; Soper, E; Aguilar, S; Cimino, J; Connolly, J; Kontorovich, A; Murray, M; Abul-Husn, N; Kenny, E. O33: An LDL-C polygenic risk score enables early identification of individuals at high risk for hypercholesterolemia who may otherwise be missed. Genetics in Medicine Open. 2026; 4:104320.

Hussien, H; Moore, DL; Nimri, S; Bilaver, LA; Warren, CM; Wlodarski, M; Jiang, J; Assa'ad, AH; Sharma, HP; Moy, JN; Newmark, P; Fox, S; Gupta, RS; Mahdavinia, M. The age of eczema onset and multiple food allergies. Annals of Allergy, Asthma and Immunology. 2026; 136(3):340-345.e1.

Jolma, A; Laverty, KU; Fathi, A; Yang, AWH; Yellan, I; Vorontsov, IE; Gralak, AJ; Kribelbauer-Swietek, JF; Inukai, S; Razavi, R; Bucher, P; Deplancke, B; Kulakovskiy, IV; Hughes, TR. An expanded codebook of human transcription factor DNA-binding specificity. Nature. 2026; 657(8130):275-283.

Jolma, A; Hernandez-Corchado, A; Yang, AWH; Fathi, A; Laverty, KU; Brechalov, A; Razavi, R; Albu, M; Zheng, H; Kulakovskiy, IV; Najafabadi, HS; Hughes, TR. GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors. Nature Methods. 2026.

Katko, A; Korinfskaya, S; Bejjani, AT; Owoeye, SM; Yang, ZF; Rudrapatna, AN; Potter, S; Wayman, JA; Kotliar, M; Kottyan, LC; Barski, A; Miraldi, ER. Gene regulatory network determinants of rapid recall in human memory CD4+ T cells. Cell reports. 2026; 45(4):117103.

Ketchem, CJ; Gabryszewski, SJ; Rothenberg, ME. Artificial intelligence in the detection and management of eosinophilic gastrointestinal diseases: Applications, challenges, and future outlook. Journal of Allergy and Clinical Immunology. 2026; 157(1):56-58.

Kottyan, LC. Beyond scale in food allergy genetics. Journal of Allergy and Clinical Immunology. 2026; 158(1):46-47.

Kottyan, LC; Richards, S; Tracy, ME; Lawson, LP; Kottyan, IC; Curwin, A; Cobb, B; Esslinger, S; Gerwe, M; Morgan, J; Muglia, L; Harley, JB; Chepelev, I; Kaufman, KM. Sequencing and health data resource of children of African ancestry. Genetics in Medicine. 2026; 28(3):101660.

Lawson, LP; Prows, CA; Cortopassi, J; Davis, KW; Head, M; Martin, LJ; Perez, EF; Sobowale, A; Abul-Husn, NS; Bangash, H; Wiesner, GL; Xian, S; Jarvik, GP; Kullo, I. Return of genome-informed risk-assessment results for common conditions to 23,840 adults and children: An eMERGE network study. American Journal of Human Genetics. 2026; 113(4):678-691.

Lenti, MV; Rossi, CM; Dellon, ES; Lucendo, AJ; Sawada, A; Cianferoni, A; Krishnan, U; Collins, MH; Savarino, EV; Di Sabatino, A. Eosinophilic gastrointestinal diseases. Nature Reviews Disease Primers. 2026; 12(1).

Lim, WK; Wipperman, MF; Rothenberg, ME; Collins, MH; Hamon, SC; Chehade, M; Spergel, JM; Gayvert, KM; Ehmann, PJ; Horowitz, JE; Ajithdoss, DK; Herman, G; Yancopoulos, GD; Hamilton, JD. Dupilumab normalizes the eosinophilic esophagitis disease transcriptome. Journal of Allergy and Clinical Immunology. 2026; 158(2):542-554.

Limdi, N; Beasley, TM; Cortopassi, J; Davis, B; Bangash, H; Chen, J; Chisholm, RL; Chung, WK; Cimino, JJ; Connolly, J; Weng, C; Wiesner, G; Abul-Husn, NS; Veenstra, DL. The Electronic Medical Records and Genomics study: Design and analytic framework for assessing the impact of genome-informed risk assessments. American Journal of Human Genetics. 2026; 113(4):664-677.

Malysheva, V; Ray-Jones, H; Lakes, N; Brown, RA; Cazares, TA; Clay, O; Ohayon, DE; Artemov, P; Wayman, JA; Yang, ZF; Wallace, C; Miraldi, ER; Waggoner, SN; Spivakov, M. High-resolution promoter interaction analysis implicates genes involved in activation of type 3 innate lymphoid cells in immune disease risk. Nature Genetics. 2026; 58(8):1953-1966.

Minaldi, E; Chow, T; Risma, K; Rukasin, C; Norton, A. Outcomes of Pediatric analgesic allergy challenges and the validation of the I3A tool in four U.S. Cohorts. Journal of Allergy and Clinical Immunology. 2026; 157(2):ab102.

Miracle, CE; Zevit, N; Gerster, E; Kliewer, K; Rothenberg, ME. Prevalence and features of eosinophilic gastrointestinal disorders using the large real-world TriNetX database. Journal of Allergy and Clinical Immunology: Global. 2026; 5(5):100762.

Mitul, MT; Sun, Y; Yates, TB; Sureshchandra, S; Kastenschmidt, JM; Sorn, AM; Wagoner, ZW; Joloya, EM; Nair, AK; Daugherty, A; Weirauch, MT; Kottyan, LC; Gewurz, BE; Wagar, LE. A tonsil organoid model reveals Epstein-Barr virus-infected germinal center B cell states during primary infection. Proceedings of the National Academy of Sciences of the United States of America. 2026; 123(33):e2603586123.

Naderian, M; Smith, JL; Dikilitas, O; Hamed, ME; Abul-Husn, NS; Connolly, JJ; Cortopassi, JB; Feng, Q; Hanks, SC; Irvin, R; Wiesner, G; Manolio, TA; Sharp, RR; Kullo, IJ. Additive value of polygenic risk and family history for coronary heart disease risk stratification in two diverse US cohorts. American Journal of Human Genetics. 2026; 113(8):1618-1629.

Namjou, B; Lape, M; Weirauch, MT; Kaufman, KM; Kottyan, LC. Polygenic risk score and phenome-wide association study of the Epstein-Barr virus antibody response. Frontiers in Genetics. 2026; 17:1786510.

Natale, MA; Jindal, R; Rothenberg, ME; Zhang, S. Emerging insights into the presentation, pathophysiology, and management of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2026; 158(2):331-341.

Nguyen, NNM; Brady, AE; Russi, A; Pham, G; Li, B; Turner, LH; Kotliar, M; Barski, A; Sun, X; Way, SS. Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance. Proceedings of the National Academy of Sciences of the United States of America. 2026; 123(13):e2519393123.

Orange, JS; Chinen, J; Horner, CC; Kobrynski, LJ; Ballow, M; Butte, MJ; Chandrakasan, S; Chinn, IK; Satter, LF; Freeman, AF; Greenhawt, M; Ledford, DK; Mosnaim, G; Wang, J. 2025 Inborn errors of immunity practice parameter: Guidance from the Joint Task Force on Practice Parameters, the American Academy of Allergy, Asthma & Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI) and the Clinical Immunology Society (CIS). Annals of Allergy, Asthma and Immunology. 2026; 136(4):426-493.e1.

Pachano, T; Leng, H; Dugied, G; Tribble, T; Loubiere, V; Lee, Y; Rauh, F; Manon, V; Yuan, K; Nurtanto, J; Chen, J; Schramek, D; Stark, A; Taipale, M. Systematic discovery of pathogen effector functions across human pathogens and pathways. Cell. 2026; 189(17):5429-5448.e14.

Ponda, P; Bird, JA; Bufford, JL; Cianferoni, A; Faig, W; Kleiner, GI; Lang, A; Scurlock, AM; Shreffler, WG; Varshney, P; Sicherer, SH; Assa'ad, A. Food oral immunotherapy patient selection, dosing, and monitoring practices among a network of US food allergy centers. Journal of Allergy and Clinical Immunology: In Practice. 2026.

Robson, M; Harville, K; Hoelker, C; Wendling, T; Risma, K. A Novel Framework for Categorizing Classical Allergy from Multi-Dose Intolerance in Children Undergoing Amoxicillin Challenges. Journal of Allergy and Clinical Immunology. 2026; 157(2):ab106.

Robson, M; Harville, K; Hoelker, C; Wendling, T; Risma, K. Beyond Single-Dose Allergy: Developing Predictive Tools for Multi-Dose Intolerance in Pediatric Amoxicillin Challenges. Journal of Allergy and Clinical Immunology. 2026; 157(2):ab292.

Robson, M. Updates in Pediatric Drug Allergy. Current Allergy and Asthma Reports. 2026; 26(1):11.

Rochman, M; Rothenberg, ME. Immune functions of the esophagus. Journal of Allergy and Clinical Immunology. 2026; 157(2):316-328.

Rochman, Y; Melamed, JR; Klingler, AM; Kotliar, M; Rochman, M; Caldwell, JM; Felton, JM; Osswald, GA; Muscat-Rivera, J; Kegel, M; Barski, A; Lewkowich, IP; Weissman, D; Rothenberg, ME. Antigen-specific messenger RNA lipid nanoparticle therapy with mTOR inhibition promotes regulatory T cells and limits allergy. Journal of Allergy and Clinical Immunology. 2026.

Rosado-Tristani, DA; Albu, M; Chen, X; Sasse, A; Laverty, KU; Ray, D; Tam, CL; Ernst, K; Lawson, LP; Morris, QD; Hughes, TR; Weirauch, MT. CisBP-RNA: a web resource for eukaryotic RNA-binding proteins and their motifs. Nucleic Acids Research (NAR). 2026; 54(D1):D98-D105.

Rubin, CJ; Lee, LW; Assa'ad, A; Lara-Corrales, I; Katabi, D; Rahul, H; Ruan, S; Krishna, P; Hristov, R; Chandross, KJ; Gupta, R; Ardeleanu, M; Zhang, A. Emerald Touchless Sensor Quantifies Nighttime Scratching and Sleep Quality in Children With Atopic Dermatitis: PEDISTAD EMERALD Study. Dermatology and Therapy. 2026.

Rukasin, CRF; Chow, TG; Van Stechelman, P; Norton, AE; Stone, CA; Hoelker, C; Risma, K; Koo, G. Direct challenges are safe and effective in children with low-risk allergies to oral cephalosporins. Journal of Allergy and Clinical Immunology: In Practice. 2026; 14(1):286-288.e1.

Sasse, A; Ray, D; Laverty, KU; Tam, CL; Albu, M; Zheng, H; Levdansky, Y; Lyudovyk, O; Dalal, T; Nie, K; Valkov, E; Weirauch, MT; Hughes, TR; Morris, Q. A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function. Nature Biotechnology. 2026; 44(7):1226-1236.

Schwartz, J; Pilipenko, V; He, H; Bolton, S; Collins, MH; Felton, JM; Oswald, GA; Zehnder, LJ; Kemtur, P; Mukkada, VA; Martin, LJ; Rothenberg, ME; Zhang, S. Peripheral blood markers of pediatric eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2026; 157(4):1002-1005.

Sharlin, CS; Yamada, S; Maekawa, Y; Osonoi, K; Matsuyama, K; Osswald, GA; Rochman, M; Taylor, RJ; Yamaguchi, M; Tanaka, Y; Wen, T; Dellon, ES; Rothenberg, ME; Shoda, T. Effects of proton pump inhibitors on remodeling and fibrosis in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2026; 157(5):1114-1126.

Tompkin, JE; Saelao, P; Kruczalak, J; Yeo, H; Olafson, PU; Sim, SB; Oyen, K; Kelley, M; Corpuz, RL; Scheffler, B; Dergousoff, SJ; Soghigian, J; Noh, SM; Benoit, JB. Genome sequencing and multi-stage, blood-feeding, and tissue-specific transcriptome atlas of the Rocky Mountain wood tick provide a critical resource for this vector. Insect Biochemistry and Molecular Biology. 2026; 195:104646.

Trimarchi, MP; Namjou-Khales, B; Ben-Baruch Morgenstern, N; Rochman, M; Chen, X; Osswald, GA; Besse, JA; Shook, MS; Caldwell, JM; Lape, M; Constantine, GM; Martin, LJ; Kottyan, LC; Rothenberg, ME. Multitrait analysis of genome-wide association studies expands eosinophilic esophagitis genetic susceptibility and polygenic risk scores. Journal of Allergy and Clinical Immunology. 2026; 158(2):492-511.

Warren, AN; Gonzalez-Orozco, M; Kuzmin, I; Parameswaran, S; Soto Acosta, R; Kalveram, B; Van Tol, S; Hage, A; Behera, P; Peñaflor-Tellez, Y; Weirauch, MT; Freiberg, A; Bukreyev, A; Rajsbaum, R. PTPN13 Contributes to Ebola Virus-Induced Immune Dysregulation via Dephosphorylation of IRF3 and PI3K-p85. Viruses. 2026; 18(7).

Yamada, S; Aoki, M; Sogo, T; Shoda, T. Increasing Diagnostic Rate of Pediatric Eosinophilic Gastrointestinal Diseases: A Retrospective Analysis of 18 Years of Experience. Journal of Allergy and Clinical Immunology. 2026; 157(2):ab61.

Zhang, S; Pilipenko, V; He, H; Collins, M; Felton, J; Osswald, G; Martin, L; Rothenberg, M. Peripheral blood markers of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2026; 157(2):ab62.