Allergy and Immunology
Publications

Publications

Abe, Y; Kofman, ER; Ouyang, Z; Cruz-Becerr, G; Spann, NJ; Seidman, JS; Troutman, TD; Stender, JD; Taylor, H; Fan, W; Evans, RM; Kadonaga, JT; Rosenfeld, MG; Glass, CK. A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of USA. 2024; 121:e2316104121.

Abonia, JP. Therapeutic management of eosinophilic esophagitis. Encyclopedia of Food Allergy. : Elsevier; Elsevier; 2024.

Abonia, JP; Rudman Spergel, AK; Hirano, I; Shoda, T; Zhang, X; Martin, LJ; Mukkada, VA; Putnam, PE; Blacklidge, M; Neilson, D; Menard-Katcher, P; Falk, G; Gonsalves, NP; Peterson, K. Losartan Treatment Reduces Esophageal Eosinophilic Inflammation in a Subset of Eosinophilic Esophagitis. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:2427-2438.e3.

Altrichter, S; Giménez-Arnau, AM; Bernstein, JA; Metz, M; Bahadori, L; Bergquist, M; Brooks, L; Ho, CN; Jain, P; Lukka, PB; Lynn, L; Assaad, A; Assaad, A; Assaad, A. Benralizumab does not elicit therapeutic effect in patients with chronic spontaneous urticaria: results from the phase IIb multinational randomized double-blind placebo-controlled ARROYO trial. British Journal of Dermatology. 2024; 191:187-199.

Armstrong, ND; Patki, A; Srinivasasainagendra, V; Ge, T; Lange, LA; Kottyan, L; Namjou, B; Shah, AS; Rasmussen-Torvik, LJ; Jarvik, GP; Meigs, JB; Karlson, EW; Limdi, NA; Irvin, MR; Tiwari, HK. Variant level heritability estimates of type 2 diabetes in African Americans. Scientific Reports. 2024; 14:14009.

Bahna, SL; Assa'ad, AH; Bellanti, JA; Bernstein, DI; Davis, CM; Greenberger, PA; Wood, RA. Where is academic medicine going?: Part 2. Academic career and patient care. Annals of Allergy, Asthma, and Immunology. 2024; 133:364-365.

Bahna, SL; Assa'ad, AH; Bellanti, JA; Bernstein, DI; Davis, CM; Greenberger, PA; Wood, RA. Where is academic medicine going?: Part 1. Medical education and research. Annals of Allergy, Asthma, and Immunology. 2024; 133:242-243.

Bannon, M; Thivalapill, N; Fithian, E; Jiang, J; Herbert, L; Fox, S; Warren, C; Sharma, H; Mahdavinia, M; Gupta, R; Bilaver, L; Assa'Ad, A. Differences in familiarity with oral immunotherapy among caregivers of White and Black children with food allergy. Annals of Allergy, Asthma, and Immunology. 2024; 133:581-584.e3.

Ben-Baruch Morgenstern, N; Rochman, M; Kotliar, M; Dunn, JL M; Mack, L; Besse, J; Natale, MA; Klingler, AM; Felton, JM; Caldwell, JM; Barski, A; Rothenberg, ME. Single-cell RNA-sequencing of human eosinophils in allergic inflammation in the esophagus. Journal of Allergy and Clinical Immunology. 2024; 154:974-987.

Ben-Baruch Morgenstern, N; Rochman, Y; Caldwell, JM; Collins, MH; Mukkada, VA; Putnam, PE; Bolton, SM; Kliewer, KL; Rothenberg, ME. TH2 cell compensatory effect following benralizumab treatment for eosinophilic gastritis. Journal of Allergy and Clinical Immunology. 2024; 154:1325-1332.e2.

Bernstein, JA; Bernstein, JS; Makol, R; Ward, S. Allergic Rhinitis: A Review. Journal of the American Medical Association (JAMA). 2024; 331:866-877.

Bognanni, A; Fiocchi, A; Arasi, S; Chu, DK; Ansotegui, I; Assa'ad, AH; Bahna, SL; Berni Canani, R; Bozzola, M; Dahdah, L; Warner, A; Wong, GW K; Schünemann, HJ; Brozek, JL. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guideline update - XII - Recommendations on milk formula supplements with and without probiotics for infants and toddlers with CMA. World Allergy Organization Journal. 2024; 17:100888.

Bognanni, A; Firmino, RT; Arasi, S; Chu, DK; Chu, AW L; Waffenschmidt, S; Agarwal, A; Dziechciarz, P; Horvath, A; Mihara, H; Waserman, S; Fiocchi, A; Schünemann, HJ; Brozek, JL. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guideline update - XI - Milk supplement/replacement formulas for infants and toddlers with CMA - Systematic review. World Allergy Organization Journal. 2024; 17:100947.

Castells, M; Giannetti, MP; Hamilton, MJ; Novak, P; Pozdnyakova, O; Nicoloro-SantaBarbara, J; Jennings, SV; Francomano, C; Kim, B; Glover, SC; Lyons, JJ; Togias, A; Wheatley, L; Milner, JD. Mast cell activation syndrome: Current understanding and research needs. Journal of Allergy and Clinical Immunology. 2024; 154:255-263.

Chehade, M; Dellon, ES; Spergel, JM; Collins, MH; Rothenberg, ME; Pesek, RD; Hirano, I; Liu, R; Laws, E; Mortensen, E; Patel, N; Yancopoulos, GD; Glotfelty, L; Maloney, J. Dupilumab for Eosinophilic Esophagitis in Patients 1 to 11 Years of Age. The New England Journal of Medicine. 2024; 390:2239-2251.

Correia Marques, M; Rubin, D; Shuldiner, EG; Datta, M; Schmitz, E; Gutierrez Cruz, G; Patt, A; Bennett, E; Grom, A; Foell, D; Woo, P; Yeung, RS M; Zeft, AS; Zeggini, E. Enrichment of Rare Variants of Hemophagocytic Lymphohistiocytosis Genes in Systemic Juvenile Idiopathic Arthritis. Arthritis and Rheumatology. 2024; 76:1566-1572.

Dai, D; Gu, S; Han, X; Ding, H; Jiang, Y; Zhang, X; Yao, C; Hong, S; Zhang, J; Shen, Y; Kottyan, LC; Weirauch, MT; Vinuesa, CG; Shen, N. The transcription factor ZEB2 drives the formation of age-associated B cells. Science. 2024; 383:413-421.

Dourson, AJ; Fadaka, AO; Warshak, AM; Paranjpe, A; Weinhaus, B; Queme, LF; Hofmann, MC; Evans, HM; Donmez, OA; Forney, C; Weirauch, MT; Kottyan, LC; Lucas, D; Deepe, GS; Jankowski, MP. Macrophage memories of early-life injury drive neonatal nociceptive priming. Cell Reports. 2024; 43:114129.

Dunn, JL M; Szep, A; Gonzalez Galan, E; Zhang, S; Marlman, J; Caldwell, JM; Troutman, TD; Rothenberg, ME. Eosinophil specialization is regulated by exposure to the esophageal epithelial microenvironment. Journal of Leukocyte Biology. 2024; 116:1007-1020.

Fulkerson, PC; Lussier, SJ; Bendixsen, CG; Castina, SM; Gebretsadik, T; Marlin, JS; Russell, PB; Seibold, MA; Everman, JL; Moore, CM; Zoratti, EM; Togias, A; Hartert, TV; Heros Study Team, OB O T. Human Epidemiology and Response to SARS-CoV-2 (HEROS): objectives, design, and enrollment results of a 12-city remote observational surveillance study of households with children, using direct-to-participant methods. American Journal of Epidemiology. 2024; 193:1329-1338.

Furuta, GT; Dellon, ES; Straumann, A; Gonsalves, N; Rothenberg, ME; Hirano, I. Building and implementing a research infrastructure for eosinophilic gastrointestinal diseases. Journal of Allergy and Clinical Immunology. 2024; 153:1536-1539.

Ganguly, S; Rosenthal, SB; Ishizuka, K; Troutman, TD; Rohm, TV; Khader, N; Aleman-Muench, G; Sano, Y; Archilei, S; Soroosh, P; Loomba, R; Glass, CK; Brenner, DA; Dhar, D. Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2. Proceedings of the National Academy of Sciences of USA. 2024; 121:e2405746121.

Gautam, Y; Satish, L; Ramirez, S; Grashel, B; Biagini, JM; Martin, LJ; Rothenberg, ME; Khurana Hershey, GK; Mersha, TB. Joint genotype and ancestry analysis identify novel loci associated with atopic dermatitis in African American population. Human Genetics and Genomics Advances. 2024; 5:100350.

Hirano, I; Dellon, ES; Falk, GW; Gonsalves, NP; Furuta, GT; Bredenoord, AJ; Straumann, A; Schoepfer, A; Chang, JW; Peterson, K; Vanuytsel, T; Woodland, P; Greuter, T; Kuang, FL. Ascending to New Heights for Novel Therapeutics for Eosinophilic Esophagitis. Gastroenterology. 2024; 166:1-10.

Kay-Green, S; Thivalapill, N; Bilaver, L; Jiang, J; Assa'ad, A; Fox, S; Sharma, H; Mahdavinia, M; Herbert, L; Warren, C; Gupta, R. Food Allergy Reaction Severity and Management in a Diverse Population. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:681-685.

Kim, B; Rothenberg, ME; Sun, X; Bachert, C; Artis, D; Zaheer, R; Deniz, Y; Rowe, P; Cyr, S. Neuroimmune interplay during type 2 inflammation: Symptoms, mechanisms, and therapeutic targets in atopic diseases. Journal of Allergy and Clinical Immunology. 2024; 153:879-893.

Kim, T; Martínez-Bonet, M; Wang, Q; Hackert, N; Sparks, JA; Baglaenko, Y; Koh, B; Darbousset, R; Laza-Briviesca, R; Chen, X; Weirauch, MT; Raychaudhuri, S; Rao, DA; Nigrovic, PA. Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Nature Communications. 2024; 15:2150.

Lanier, K; Scherzer, R; Coletta, C; Ogbogu, PU; Risma, KA; Redmond, M. Factors Influencing Career Choice of Allergy and Immunology Fellows-in-Training: A Work Group Report of the AAAAI Program Directors Assembly Executive Committee. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:627-632.e4.

Lee, TM; Miller, E; Sridhar, A; Fan, X; Dexheimer, PJ; Bansal, N; Godown, J; Hsu, DT; Kantor, P; Kirmani, S; Ware, SM; Chung, WK; Wilkinson, JD; Lipshultz, SE. Pediatric cardiomyopathy illustrates the importance of reinterpreting the significance of genetic variants. Progress in Pediatric Cardiology. 2024; 74:101732.

Lennon, NJ; Kottyan, LC; Kachulis, C; Abul-Husn, NS; Arias, J; Belbin, G; Below, JE; Berndt, SI; Chung, WK; Cimino, JJ; Weng, C; Wiesner, GL; Yin, X; Kenny, EE. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature Medicine. 2024; 30:480-487.

Lewis, AC F; Chisholm, RL; Connolly, JJ; Esplin, ED; Glessner, J; Gordon, A; Green, RC; Hakonarson, H; Harr, M; Holm, IA; Sterling, R; Terek, S; Wei, WQ; Fullerton, SM. Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network. The American Journal of Human Genetics. 2024; 111:999-1005.

Li, G; Mahajan, S; Ma, S; Jeffery, ED; Zhang, X; Bhattacharjee, A; Venkatasubramanian, M; Weirauch, MT; Miraldi, ER; Grimes, HL; Sheynkman, GM; Tilburgs, T; Salomonis, N. Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. Science Translational Medicine. 2024; 16:eade2886.

Li, Y; Devonshire, A; Huang, B; Andorf, S. Risk subgroups and intervention effects among infants at high risk for peanut allergy: A model for clinical decision making. Clinical and Experimental Allergy. 2024; 54:185-194.

Lopez-Nunez, O; Bernieh, A; Kliewer, KL; Kemtur, P; Bolton, SM; Mukkada, VA; Schablein, R; Woods, C; Rothenberg, ME; Collins, MH. Transnasal Endoscopy Acquires Esophageal Biopsies Adequate for Comprehensive Pathology Evaluation in Patients With Eosinophilic Esophagitis. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2024; 27:327-334.

Macaluso, M; Rothenberg, ME; Ferkol, T; Kuhnell, P; Kaminski, HJ; Kimberlin, DW; Benatar, M; Chehade, M. Impact of the COVID-19 Pandemic on People Living With Rare Diseases and Their Families: Results of a National Survey. JMIR Public Health and Surveillance. 2024; 10:e48430.

Martin, LJ; Zhang, X; Chehade, M; Davis, CM; Dellon, ES; Falk, GW; Gupta, SK; Hirano, I; Hiremath, GS; Katzka, DA; Yang, GY; Furuta, GT; Rothenberg, ME; Aceves, SS. Long-term durability between parent and child patient-reported outcomes in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2024; 154:1232-1240.e12.

Matsuyama, K; Yamada, S; Sato, H; Zhan, J; Shoda, T. Advances in omics data for eosinophilic esophagitis: moving towards multi-omics analyses. Journal of Gastroenterology. 2024; 59:963-978.

McDonnell, J; Cousins, K; Younger, ME M; Lane, A; Abolhassani, H; Abraham, RS; Al-Tamemi, S; Aldave-Becerra, JC; Al-Faris, EH; Alfaro-Murillo, A; Lim, XR; Lopes, JP; López, AL; Tarquini, L. COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET Report. Journal of Clinical Immunology. 2024; 44:86.

Melhem, RA; Hassoun, Y. Advancements in Biologic Therapies for Eosinophilic Gastrointestinal Diseases: A Comprehensive Review. Immunology and Allergy Clinics of North America. 2024; 44:615-627.

Oliva, S; Aceves, SS; Zevit, N; Rothenberg, ME; Furuta, GT; Dellon, ES. Crafting a Therapeutic Pyramid for Eosinophilic Esophagitis in the Age of Biologics. Clinical Gastroenterology and Hepatology. 2024; 22:1763-1769.

Papadopoulou, A; Amil-Dias, J; Auth, MK-H; Chehade, M; Collins, MH; Gupta, SK; Gutiérrez-Junquera, C; Orel, R; Vieira, MC; Zevit, N; Strauman, A; Thapar, N; Yang, G; Furuta, GT. Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis. Journal of Pediatric Gastroenterology and Nutrition. 2024; 78:122-152.

Pfirrman, S; Devonshire, A; Winslow, A. Environmental Interventions for Preventing Atopic Diseases. Current Allergy and Asthma Reports. 2024; 24:233-251.

Potter, SJ; Zhang, L; Kotliar, M; Wu, Y; Schafer, C; Stefan, K; Boukas, L; Qu’d, D; Bodamer, O; Simpson, BN; Barski, A; Lindsley, AW; Bjornsson, HT. KMT2D regulates activation, localization, and integrin expression by T-cells. Frontiers in Immunology. 2024; 15:1341745.

Proper, SP; Dwyer, AT; Appiagyei, A; Felton, JM; Ben-Baruch Morgenstern, N; Marlman, JM; Kotliar, M; Barski, A; Troutman, TD; Rothenberg, ME; Mersha, TB; Azouz, NP. Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis. Frontiers in Allergy. 2024; 5:1323405.

Robson, M; Assa'ad, A. Food allergy: Definitions and overview. Encyclopedia of Food Allergy. : Elsevier; Elsevier; 2024.

Rochman, M; Klinger, AM; Caldwell, JM; Sadovsky, Y; Rothenberg, ME. Amniotic fluid modifies esophageal epithelium differentiation and inflammatory responses. American Journal of Physiology: Gastrointestinal and Liver Physiology. 2024; 327:G629-G639.

Rothenberg, ME; Dellon, ES; Collins, MH. Two Clinical Trials Assessing Treatments for Eosinophilic Esophagitis. Reply. The New England Journal of Medicine. 2024; 391:1067-1068.

Rothenberg, ME; Dellon, ES; Collins, MH; Bredenoord, AJ; Hirano, I; Peterson, KA; Brooks, L; Caldwell, JM; Fjällbrant, H; Grindebacke, H; McCrae, C; Sinibaldi, D; White, WI; Datto, CJ. Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis. The New England Journal of Medicine. 2024; 390:2252-2263.

Ruffner, MA; Shoda, T; Lal, M; Mrozek, Z; Muir, AB; Spergel, JM; Dellon, ES; Rothenberg, ME. Persistent esophageal changes after histologic remission in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2024; 153:1063-1072.

Sato, H; Dellon, ES; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Davis, CM; Falk, GW; Furuta, GT; Gonsalves, NP; Wechsler, JB; Yang, GY; Rothenberg, ME; Shoda, T. Clinical and molecular correlates of the Index of Severity for Eosinophilic Esophagitis. Journal of Allergy and Clinical Immunology. 2024; 154:375-386.e4.

Sato, H; Taylor, RJ; Sakai, N; Osonoi, K; Rothenberg, ME; Shoda, T. Eosinophil Involvement Outside the Esophagus in Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2024; 22:1531-1534.e2.

Sharlin, CS; Collins, MH; Bolton, SM; Osswald, GA; Safadi, GS; Kliewer, KL; Rothenberg, ME; Shoda, T; Mukkada, VA. Induction of sustained remission and reversal of pathologic transcriptome achieved with tezepelumab in an adolescent with eosinophilic esophagitis. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:3147-3149.e2.

Shoda, T; Taylor, RJ; Sakai, N; Rothenberg, ME. Common and disparate clinical presentations and mechanisms in different eosinophilic gastrointestinal diseases. Journal of Allergy and Clinical Immunology. 2024; 153:1472-1484.

Shook, MS; Lu, X; Chen, X; Edsall, LE; Granitto, M; Virolainen, SJ; Forney, C; Donmez, OA; Parameswaran, S; Fadden, C; Martin, L; Satish, L; Weirauch, MT; Kottyan, LC. Massively Parallel Analysis of Genotype-Dependent Enhancer Activity Among Atopic Dermatitis Genetic Risk Variants. 2024.

Shook, MS; Lu, X; Chen, X; Parameswaran, S; Edsall, L; Trimarchi, MP; Ernst, K; Granitto, M; Forney, C; Donmez, OA; Diouf, AA; VonHandorf, A; Rothenberg, ME; Weirauch, MT; Kottyan, LC. Systematic identification of genotype-dependent enhancer variants in eosinophilic esophagitis. The American Journal of Human Genetics. 2024; 111:280-294.

Skevaki, C; Nadeau, KC; Rothenberg, ME; Alahmad, B; Mmbaga, BT; Masenga, GG; Sampath, V; Christiani, DC; Haahtela, T; Renz, H. Impact of climate change on immune responses and barrier defense. Journal of Allergy and Clinical Immunology. 2024; 153:1194-1205.

Sun, C; Swoboda, CO; Morales, FM; Calvo, C; Petrany, MJ; Parameswaran, S; VonHandorf, A; Weirauch, MT; Lepper, C; Millay, DP. Lineage tracing of nuclei in skeletal myofibers uncovers distinct transcripts and interplay between myonuclear populations. Nature Communications. 2024; 15:9372.

Sun, KY; Bai, X; Chen, S; Bao, S; Zhang, C; Kapoor, M; Backman, J; Joseph, T; Maxwell, E; Mitra, G; Ghosh, A; Martinez, SR; Gillies, C; Gurski, L. A deep catalogue of protein-coding variation in 983,578 individuals. Nature. 2024; 631:583-592.

Underwood, B; Mills, C; Devonshire, AL; Andorf, S; Assa'ad, AH; Ramsey, R; Schwartz, JT. OIT-BRAVE questionnaire: Development and clinical implementation of a screening instrument for patient-reported difficulties during oral immunotherapy. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:2524-2526.e1.

Venter, C; Meyer, R; Groetch, M; Nowak-Wegrzyn, A; Mennini, M; Pawankar, R; Kamenwa, R; Assa'ad, A; Amara, S; Fiocchi, A; Vandenplas, Y; Waserman, S; Warner, A; Wong, GW K. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines update - XVI - Nutritional management of cow's milk allergy. World Allergy Organization Journal. 2024; 17:100931.

Viel, KC M F; Parameswaran, S; Donmez, OA; Forney, CR; Hass, MR; Yin, C; Jones, SH; Prosser, HK; Diouf, AA; Gittens, OE; Gewurz, B; Zhao, B; Kottyan, LC; Weirauch, MT. Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome. BMC Genomics. 2024; 25:273.

Virolainen, SJ; Satish, L; Biagini, JM; Chaib, H; Chang, WC; Dexheimer, PJ; Dixon, MR; Dunn, K; Fletcher, D; Forney, C; Shook, M; Weirauch, MT; Khurana Hershey, GK; Kottyan, LC. Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. JCI insight. 2024; 9:e178258.

Wang, Q; Kim, T; Martínez-Bonet, M; Aguiar, VR C; Sim, S; Cui, J; Sparks, JA; Chen, X; Todd, M; Wauford, B; Marion, MC; Langefeld, CD; Weirauch, MT; Gutierrez-Arcelus, M; Nigrovic, PA. High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. Nature Communications. 2024; 15:6804.

Winslow, A; Mills, C; Schwartz, JT; Assa'ad, A. Implementing Food Oral Immunotherapy Into Clinical Practice: Quality and Safety Perspectives From a US Academic Center. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:1159-1169.

Wright, BL; Abonia, JP; Abud, EM; Aceves, SS; Ackerman, SJ; Braskett, M; Chang, JW; Chehade, M; Constantine, GM; Davis, CM; Spergel, JM; Uchida, AM; Wechsler, JB; Pesek, RD. Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting. Journal of Allergy and Clinical Immunology. 2024; 154:882-892.

Zhang, S; Caldwell, J; Rochman, M; Collins, M; Rothenberg, M. Machine Learning-Based Characterization of Esophageal Mast Cells in Eosinophilic Esophagitis Reveals Mast Cell Degranulation. Journal of Allergy and Clinical Immunology. 2024; 153:ab222.

Zhang, S; Caldwell, JM; Rochman, M; Collins, MH; Rothenberg, ME. Machine learning-based identification and characterization of mast cells in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2024; 153:1381-1391.e6.