Scott M. Bolton, MD
- Attending Physician, Division of Gastroenterology, Hepatology and Nutrition
- Assistant Professor, UC Department of Pediatrics
- scott.bolton@cchmc.org
- Board Certified
About
ScB: Brown University, Providence, RI, 2007.
MD: Vanderbilt University, Nashville, TN, 2011.
Residency: Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH, 2011-2014.
Fellowship: Pediatric Gastroenterology, Northwestern University/ Ann & Robert H. Lurie Children’s Hospital, Chicago, IL, 2015-2018.
Certification: General Pediatrics, 2014.
Interests
Eosinophilic gastrointestinal disorders; esophageal disorders; general pediatric gastroenterology
Services and Specialties
Interests
Eosinophilic gastrointestinal disorders; novel endoscopic approaches to disease evaluation and monitoring; disease outcomes
Research Areas
Publications
Role of mast cells in eosinophilic esophagitis. Current Opinion in Gastroenterology. 2022; 38:541-548.
Defining the Patchy Landscape of Esophageal Eosinophilia in Children With Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2022; 20:1971-1976.e2.
Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission. Journal of Allergy and Clinical Immunology. 2022; 149:2062-2077.
Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022; 162:1635-1649.
Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022; 162:439-453.
Developing a standardized approach for assessing mast cells and eosinophils on tissue biopsies: A Work Group Report of the AAAAI Allergic Skin Diseases Committee. Journal of Allergy and Clinical Immunology. 2021; 148:964-983.
Mast Cell Infiltration Is Associated With Persistent Symptoms and Endoscopic Abnormalities Despite Resolution of Eosinophilia in Pediatric Eosinophilic Esophagitis. The American Journal of Gastroenterology (Elsevier). 2020; 115:224-233.
Eosinophilic Esophagitis Reference Score Accurately Identifies Disease Activity and Treatment Effects in Children. Clinical Gastroenterology and Hepatology. 2018; 16:1056-1063.
Eosinophilic Esophagitis in Children: Endoscopic Findings at Diagnosis and Post-intervention. Current Gastroenterology Reports. 2018; 20:4.
Induction of sustained remission and reversal of pathologic transcriptome achieved with tezepelumab in an adolescent with eosinophilic esophagitis. The Journal of Allergy and Clinical Immunology: in Practice. 2024; 12:3147-3149.e2.
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