MS: Pharmaceutical Sciences with Specialization in Drug Development, University of Cincinnati, College of Pharmacy, Cincinnati, OH, 2010.
Post-doctoral Research Fellow: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2008.
PhD: Molecular and Developmental Biology, University of Cincinnati, College of Medicine, Cincinnati, OH, 2003.
BS: Biology, John Carroll University, University Heights, OH, 1998.
Regulations, management, and coordination of clinical research trials in rare lung diseases, specifically pulmonary alveolar proteinosis (PAP); pathogenesis of PAP; developing and validating clinical research tests to diagnose PAP; evaluating several therapeutic options for individuals with PAP; translational pulmonary science; rare lung disease clinical research diagnostic testing; diagnosis of individuals with hereditary or autoimmune PAP clinical trials; National PAP Registry; inhaled GM-CSF treatment for individuals with autoimmune PAP and hereditary PAP; safety and efficacy of Pioglitazone for autoimmune PAP patients
Pulmonary Biology
Pulmonary hypertension during high-dose GM-CSF therapy of autoimmune pulmonary alveolar proteinosis. Pulmonary Circulation. 2024; 14:e70020.
A toxicology study of Csf2ra complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice. Molecular Therapy-Methods & Clinical Development. 2024; 32:101213.
Disseminated nocardiosis and anti-GM-CSF antibodies. European Journal of Clinical Microbiology and Infectious Diseases: an international journal on pathogenesis, diagnosis, epidemiology, therapy, and prevention of infectious diseases. 2024; 43:1003-1007.
Human inherited CCR2 deficiency underlies progressive polycystic lung disease. Cell. 2024; 187:390-408.e23.
Inhaled recombinant GM-CSF reduces the need for whole lung lavage and improves gas exchange in autoimmune pulmonary alveolar proteinosis patients. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2024; 63:2301233.
Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function. Frontiers in Immunology. 2023; 13:1023553.
A dried blood spot test for diagnosis of autoimmune pulmonary alveolar proteinosis. Journal of Immunological Methods. 2022; 511:113366.
Two-year follow-up of exposure, engineering controls, respiratory protection and respiratory health among workers at an indium-tin oxide (ITO) production and reclamation facility. Occupational and Environmental Medicine. 2022; 79:550-556.
Signal Transducer and Activator of Transcription 5B Deficiency-associated Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2022; 205:1245-1250.
Autoimmune Pulmonary Alveolar Proteinosis. American Journal of Respiratory and Critical Care Medicine. 2022; 205:1016-1035.