I’m a researcher interested in monogenic and multigenic human diseases, personalized medicine, genomics and bioinformatics. I have extensive academic and industry experience.

For several decades, I worked at the Pasteur Institute, the University of Michigan and Stanford University. During my PhD thesis, I was the first researcher to map the first genes involved in hearing loss. My postdoctoral work led to the establishment of the first Microarray Technology Core at the Cancer Center at the University of Michigan, and I was one of the founders of the Stanford Diabetes Research Center. I served as director of its Diabetes Genomics Analysis Core, the Sequencing Operations Center for Genomics and Personalized Medicine, and the Stem Cell Genomics at the Stanford Center of Excellence in Stem Cell Genomics. I also served as the director of Next Generation Sequencing and DNA Building at Zymergen.

During my academic research career, I used cutting-edge technologies, including genomics, next-generation sequencing and stem cell research, to resolve key scientific issues in monogenic and multigenic human diseases, such as hearing loss, kidney diseases, muscular dystrophy, cardiomyopathy and prostate cancer. I have co-authored more than 40 high-impact publications in the field of genomics.

My high priority is leading the Genomics Sequencing Facility at Cincinnati Children’s, ensuring it has state-of-the-art technology for clinicians and researchers to provide high-quality genomics testing for patients and research discoveries. My long-term research goal is to identify and advance clinical genetic diagnostics that would lead to early intervention or prevention and contribute to a patient's well-being. I aim to build a national / international collaborative program to identify genetic causes of rare and complex disorders and enhance clinical genetic diagnosis.

I have been a researcher for over 29 years and began working at Cincinnati Children’s in 2022.