A photo of Ajay Dixit.

Ajay Dixit, MSc, PhD

  • Member, Division of Gastroenterology, Hepatology and Nutrition
  • Assistant Professor, UC Department of Pediatrics

About

PhD: Indian Institute of Science.

MSc: Osmania University.

Interests

Molecular and cellular processes underlying the protective and detrimental immune responses in acute and chronic pancreatitis; underlying factors driving unresolved inflammation, fibrosis, immune suppression, and the development of pancreatic cancer.

Research Areas

Gastroenterology Hepatology and Nutrition

Publications

Abstract A033: Blocking TNF-a producing macrophage activates antitumor immunity in pancreatic cancer via IL33. Dixit, A; Provenzano, P; Sarver, A; Zettervall, J; Huang, H; Zheng, K; Brekken, R. Cancer Research. 2024; 84:a033.

Targeting TNF-α-producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling. Dixit, A; Sarver, A; Zettervall, J; Huang, H; Zheng, K; Brekken, RA; Provenzano, PP. JCI insight. 2022; 7:e153242.

Immune Cell Metabolism and Function. Dixit, A; Singh, M. Immuno-Oncology Crosstalk and Metabolism. : Springer Nature; Springer Nature; 2022.

Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis. Tiwari, A; Tashiro, K; Dixit, A; Soni, A; Vogel, K; Hall, B; Shafqat, I; Slaughter, J; Param, N; Le, A; Deshpande, AJ; Commisso, C; Provenzano, PP; Bagchi, A. Gastroenterology. 2020; 159:1882-1897.e5.

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