A photo of Lin Fei.

Associate Professor, UC Department of Pediatrics


Biography & Affiliation


My research area of interest is biostatistics and involves theoretical aspects of ranking and selection problems. I derived some inequalities that characterize the relationship between sample sizes and the probability of making the correct selection of the best treatment groups. I am also interested in multiple testing problems related to sequential clinical trial designs.

Specifically, my work includes:

  • Statistics
  • Ranking and selection
  • Sequential testing
  • Multiple comparisons
  • Probability modeling
  • Stochastic process inference

I model biological processes such as enzyme reaction rates using exponential approximation, bile duct growth patterns using quantile regression and biochemistry evaluation transition courses.

I have been a researcher for more than 18 years. I began my work at Cincinnati Children’s in 2012. My work has been published in many respected journals, including PLoS ONE, Pediatric Blood and Cancer, Pediatric Critical Care Medicine, Cardiology in the Young, European Journal of Clinical Nutrition, Journal of Pediatric Surgery, Pancreas, Pediatric Obesity and Pediatric Nephrology.

Research Interests

Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Research Divisions



BS: Shanghai Jiaotong University, Shanghai, China, 1982.

MS: The Ohio State University, Columbus, OH, 1984.

PhD: The Ohio State University, Columbus, OH, 1992.


Glucocorticoid Receptor Polymorphisms in Children Undergoing Congenital Heart Surgery with Cardiopulmonary Bypass. Flores, S; Iliopoulos, I; Loomba, RS; Opoka, AM; Sahay, RD; Fei, L; Cooper, DS. Journal of Pediatric Intensive Care. 2020; 9:241-247.

Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease. Lam, S; Singh, R; Dillman, JR; Trout, AT; Serai, SD; Sharma, D; Sheridan, R; Su, W; Fei, L; Karns, R; et al. Hepatology Communications. 2020; 4:1680-1693.

Development and Implementation of Augmented Reality Enhanced High-Fidelity Simulation for Recognition of Patient Decompensation. Zackoff, MW; Cruse, B; Sahay, RD; Fei, L; Saupe, J; Schwartz, J; Klein, M; Geis, GL; Tegtmeyer, K. Simulation in Healthcare: Journal of the society for simulation in healthcare. 2020; Publish Ahead of Print.

Identifying Predictors of Response to Vitamin E for the Treatment of Pediatric Nonalcoholic Steatohepatitis. Yodoshi, T; Orkin, S; Arce-Clachar, AC; Bramlage, K; Su, W; Fei, L; Xanthakos, SA; Mouzaki, M. Journal of Parenteral and Enteral Nutrition. 2020; 44:1301-1307.

Validation of threshold values for pancreas thickness and T1-weighted signal intensity ratio in the pediatric pancreas. McCleary, BM; Trout, AT; Dillman, JR; Sun, Q; Fei, L; Abu-El-Haija, M. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2020; 50:1381-1386.

Microbial shifts and shorter time to bowel resection surgery associated with c. difficile in pediatric Crohn's disease. Hellmann, J; Andersen, H; Fei, L; Linn, A; Bezold, R; Lake, K; Jackson, K; Meyer, D; Dirksing, K; Bonkowski, E; et al. Inflammatory Bowel Diseases. 2020; 26:1212-1221.

Muscle Mass Is Linked to Liver Disease Severity in Pediatric Nonalcoholic Fatty Liver Disease. Yodoshi, T; Orkin, S; Clachar, AA; Bramlage, K; Sun, Q; Fei, L; Beck, AF; Xanthakos, SA; Trout, AT; Mouzaki, M. The Journal of Pediatrics. 2020; 223:93-99.e2.

Glomerular Hyperfiltration Is Associated with Liver Disease Severity in Children with Nonalcoholic Fatty Liver Disease. Yodoshi, T; Arce-Clachar, AC; Sun, Q; Fei, L; Bramlage, K; Xanthakos, SA; Flores, F; Mouzaki, M. The Journal of Pediatrics. 2020; 222:127-133.

Impact of vascular anomalies on the PTEN phenotype in children and young adults. Gurunathan, A; Ricci, K; Iacobas, I; Rednam, SP; Wusik, K; Fei, L; Hammilll, AM. Pediatric Blood and Cancer. 2020; 67.

Longitudinal characterization of olfactomedin-4 expressing neutrophils in pediatric patients undergoing bone marrow transplantation. Stark, JE; Opoka, AM; Fei, L; Zang, H; Davies, SM; Wong, HR; Alder, MN. PLoS ONE. 2020; 15:e0233738-e0233738.