A photo of Lin Fei.

Lin Fei, PhD

  • Associate Professor, UC Department of Pediatrics

About

Biography

My research area of interest is biostatistics and involves theoretical aspects of ranking and selection problems. I derived some inequalities that characterize the relationship between sample sizes and the probability of making the correct selection of the best treatment groups. I am also interested in multiple testing problems related to sequential clinical trial designs.

Specifically, my work includes:

  • Statistics
  • Ranking and selection
  • Sequential testing
  • Multiple comparisons
  • Probability modeling
  • Stochastic process inference

I model biological processes such as enzyme reaction rates using exponential approximation, bile duct growth patterns using quantile regression and biochemistry evaluation transition courses.

I have been a researcher for more than 18 years. I began my work at Cincinnati Children’s in 2012. My work has been published in many respected journals, including PLoS ONE, Pediatric Blood and Cancer, Pediatric Critical Care Medicine, Cardiology in the Young, European Journal of Clinical Nutrition, Journal of Pediatric Surgery, Pancreas, Pediatric Obesity and Pediatric Nephrology.

BS: Shanghai Jiaotong University, Shanghai, China, 1982.

MS: The Ohio State University, Columbus, OH, 1984.

PhD: The Ohio State University, Columbus, OH, 1992.

Interests

Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Research Areas

Biostatistics and Epidemiology

Publications

Effect of percutaneous electrical nerve field stimulation on mechanosensitivity, sleep, and psychological comorbidities in adolescents with functional abdominal pain disorders. Santucci, NR; King, C; El-Chammas, KI; Wongteerasut, A; Damrongmanee, A; Graham, K; Fei, L; Sahay, R; Jones, C; Cunningham, NR; et al. Neurogastroenterology and Motility. 2022; 34.

Integration of the Renal Angina Index and Urine Neutrophil Gelatinase-Associated Lipocalin Improves Severe Acute Kidney Injury Prediction in Critically Ill Children and Young Adults. Goldstein, SL; Krallman, KA; Kirby, C; Roy, JP; Collins, M; Fox, K; Schmerge, A; Wilder, S; Gerhardt, B; Chima, R; et al. Kidney International Reports. 2022; 7:1842-1849.

Clinically Meaningful Body Mass Index Change Impacts Pediatric Nonalcoholic Fatty Liver Disease. Khurana, T; Klepper, C; Fei, L; Sun, Q; Bramlage, K; Arce-Clachar, AC; Xanthakos, S; Mouzaki, M. Journal of Pediatrics. 2022.

Outcomes of combined pyloric botulinum toxin injection and balloon dilation in dyspepsia with and without delayed gastric emptying. Santucci, N; Kemme, S; El-Chammas, K; Chidambaram, M; Mathur, M; Castillo, D; Sun, Q; Fei, L; Kaul, A. Saudi Journal of Gastroenterology. 2022; 28:268-275.

Pancreas volumes and predictive factors in healthy children. Qiu, L; Dillman, JR; Sun, Q; Fei, L; Abu-El-Haija, M; Trout, AT. Pediatric Radiology. 2022.

Nonalcoholic Fatty Liver Disease in Young Children with Obesity. Klepper, C; Crimmins, NA; Orkin, S; Sun, Q; Fei, L; Xanthakos, S; Mouzaki, M. Childhood Obesity. 2022.

Serum Proteomics Uncovers Biomarkers of Clinical Portal Hypertension in Children With Biliary Atresia. Osborn, J; Mourya, R; Thanekar, U; Su, W; Fei, L; Shivakumar, P; Bezerra, JA. Hepatology Communications. 2022; 6:995-1004.

Randomized Controlled Trial of Interactive Spaced Education to Support Constipation Management by Pediatric Primary Care Providers. Mallon, D; Fei, L; Farrell, M; Anderson, JB; Klein, M. Journal of Pediatric Gastroenterology and Nutrition. 2022; 74:568-574.

BMI Metrics Are Poor Predictors of Pediatric Nonalcoholic Fatty Liver Disease Severity. Klepper, CM; Khurana, T; Sun, Q; Fei, L; Crimmins, NA; Siegel, R; Mouzaki, M. Childhood Obesity. 2022.

Non-Invasive Approaches to Estimate Liver Steatosis and Stiffness in Children With Non-Alcoholic Fatty Liver Disease. Yodoshi, T; Orkin, S; Trout, AT; Arce-Clachar, AC; Bramlage, K; Liu, C; Fei, L; Dillman, JR; Xanthakos, SA; Mouzaki, M. Journal of Pediatric Gastroenterology and Nutrition. 2022; 74:495-502.