A photo of Lin Fei.

Lin Fei, PhD

  • Professor, UC Department of Pediatrics



As a professor and researcher, I design clinical and non-clinical studies, perform data analysis and presentation and examine mathematical modeling. My primary interests are probability and statistical theory applied to medical research, including distributional theory and optimization.

My interest in this field stems from my mathematical and statistical training and quantitative research. One of my notable discoveries is the probabilistic relationship between sample size and discovery rate in clinical studies, which can be reviewed in some of my publications.

I have been a researcher for over 29 years and began working with Cincinnati Children’s in 2012.

BS: Shanghai Jiaotong University, Shanghai, China, 1982.

MS: The Ohio State University, Columbus, OH, 1984.

PhD: The Ohio State University, Columbus, OH, 1992.


Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Research Areas

Biostatistics and Epidemiology


Racial Disparities in Pediatric Inflammatory Bowel Disease Care: Differences in Outcomes and Health Service Utilization Between Black and White Children. Smith, J; Liu, C; Beck, A; Fei, L; Brokamp, C; Meryum, S; Whaley, KG; Minar, P; Hellmann, J; Denson, LA; et al. The Journal of Pediatrics. 2023; 260:113522.

Presence of Alpha 1 Antitrypsin Risk Variants is Not Associated With Histologic Severity of Pediatric NAFLD. Khan, M; Klepper, C; Orkin, S; Arce-Clachar, AC; Bramlage, K; Fei, L; Miethke, A; Kohli, R; Xanthakos, S; Mouzaki, M. Journal of Pediatric Gastroenterology and Nutrition. 2023; 77:166-170.

Recent Increase in Incidence of Severe Acute Hepatitis of Unknown Etiology in Children is Associated with Infection with Adenovirus and Other Nonhepatotropic Viruses. Peters, AL; Kim, S; Mourya, R; Asai, A; Taylor, A; Rogers, M; Campbell, K; Fei, L; Miethke, A; Balistreri, WF; et al. The Journal of Pediatrics. 2023; 259:113439.

Novel sensory trigger for gastrocolonic response. Dorfman, L; Wongteerasut, A; El-Chammas, K; Sahay, R; Fei, L; Kaul, A. Neurogastroenterology and Motility. 2023; 35:e14528.

T-cell infiltrate intensity is associated with delayed response to treatment in late acute cellular rejection in pediatric liver transplant recipients. Peters, AL; Rogers, M; Begum, G; Sun, Q; Fei, L; Leino, D; Hildeman, D; Woodle, ES. Pediatric Transplantation. 2023; 27:e14475.

Mo2013 PSYCHOLOGICAL DISTRESS IN CHILDREN WITH DISORDERS OF GUT-BRAIN INTERACTION IN COLOMBIA. Santucci, NR; Velasco, C; Cunningham, N; Li, J; Fei, L; Sun, Q; Saps, M. Gastroenterology. 2023; 164:s-953-s-954.

High amplitude propagated contractions with Glycerin versus Bisacodyl: A within-subject comparison in children undergoing colonic manometry. Mansi, S; Bahia, G; Patel, D; Dorfman, L; El-Chammas, K; Fei, L; Liu, C; Santucci, NR; Graham, K; Kaul, A. Neurogastroenterology and Motility. 2023; 35:e14544.

Nonalcoholic Fatty Liver Disease in Young Children with Obesity. Klepper, C; Crimmins, NA; Orkin, S; Sun, Q; Fei, L; Xanthakos, S; Mouzaki, M. Childhood Obesity. 2023; 19:179-185.

BMI Metrics Are Poor Predictors of Pediatric Nonalcoholic Fatty Liver Disease Severity. Klepper, CM; Khurana, T; Sun, Q; Fei, L; Crimmins, NA; Siegel, R; Mouzaki, M. Childhood Obesity. 2023; 19:139-143.

Evaluation of Chronic Constipation in Children With Autism Spectrum Disorder. Coe, A; Ciricillo, J; Mansi, S; El-Chammas, K; Santucci, N; Bali, N; Lu, PL; Damrongmanee, A; Fei, L; Liu, C; et al. Journal of Pediatric Gastroenterology and Nutrition. 2023; 76:154-159.