A photo of Lin Fei.

Associate Professor, UC Department of Pediatrics


Biography & Affiliation


My research area of interest is biostatistics and involves theoretical aspects of ranking and selection problems. I derived some inequalities that characterize the relationship between sample sizes and the probability of making the correct selection of the best treatment groups. I am also interested in multiple testing problems related to sequential clinical trial designs.

Specifically, my work includes:

  • Statistics
  • Ranking and selection
  • Sequential testing
  • Multiple comparisons
  • Probability modeling
  • Stochastic process inference

I model biological processes such as enzyme reaction rates using exponential approximation, bile duct growth patterns using quantile regression and biochemistry evaluation transition courses.

I have been a researcher for more than 18 years. I began my work at Cincinnati Children’s in 2012. My work has been published in many respected journals, including PLoS ONE, Pediatric Blood and Cancer, Pediatric Critical Care Medicine, Cardiology in the Young, European Journal of Clinical Nutrition, Journal of Pediatric Surgery, Pancreas, Pediatric Obesity and Pediatric Nephrology.

Research Interests

Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Research Divisions

Biostatistics and Epidemiology


BS: Shanghai Jiaotong University, Shanghai, China, 1982.

MS: The Ohio State University, Columbus, OH, 1984.

PhD: The Ohio State University, Columbus, OH, 1992.


Effects of Provocative Testing on Phase III Migrating Motor Complex in Children. Damrongmanee, A; El-Chammas, K; Fei, L; Liu, C; Santucci, N; Kaul, A. Journal of Pediatric Gastroenterology and Nutrition. 2021.

Development and Implementation of Augmented Reality Enhanced High-Fidelity Simulation for Recognition of Patient Decompensation. Zackoff, MW; Cruse, B; Sahay, RD; Fei, L; Saupe, J; Schwartz, J; Klein, M; Geis, GL; Tegtmeyer, K. Simulation in Healthcare. 2021; 16:221-230.

Body composition measured by bioelectrical impedance analysis is a viable alternative to magnetic resonance imaging in children with nonalcoholic fatty liver disease. Orkin, S; Yodoshi, T; Romantic, E; Hitchcock, K; Arce-Clachar, AC; Bramlage, K; Sun, Q; Fei, L; Xanthakos, SA; Trout, AT; et al. Journal of Parenteral and Enteral Nutrition. 2021.

Establishing Objective Measures of Clinical Competence in Undergraduate Medical Education Through Immersive Virtual Reality. Zackoff, MW; Young, D; Sahay, RD; Fei, L; Real, FJ; Guiot, A; Lehmann, C; Klein, M. Ambulatory Pediatrics. 2021; 21:575-579.

Effect of a Practice-wide Anti-TNF Proactive Therapeutic Drug Monitoring Program on Outcomes in Pediatric Patients with Inflammatory Bowel Disease. Lyles, JL; Mulgund, AA; Bauman, LE; Su, W; Fei, L; Chona, DL; Sharma, P; Etter, RK; Hellmann, J; Denson, LA; et al. Inflammatory Bowel Diseases. 2021; 27:482-492.

Olfactomedin 4-Positive Neutrophils Are Upregulated after Hemorrhagic Shock. Kassam, AF; Levinsky, NC; Mallela, JP; Angel, K; Opoka, A; Lahni, P; Sahay, RD; Fei, L; Nomellini, V; Wong, HR; et al. American Journal of Respiratory Cell and Molecular Biology. 2021; 64:216-223.

Total pancreatectomy with islet autotransplantation reduces resource utilization in pediatric patients. Kassam, AF; Cortez, AR; Johnston, ME; Zang, H; Fei, L; Lin, TK; Abu-El-Haija, M; Nathan, JD. American Journal of Surgery. 2021.

Four Biomarkers Linked to Activation of Cluster of Differentiation 8-Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure. Leonis, MA; Miethke, AG; Fei, L; Maynor, S; Chapin, CA; Bleesing, JJ H; Alonso, EM; Squires, RH. Hepatology. 2021; 73:233-246.

Can Baseline Characteristics be Used to Predict Liver Disease Outcomes in Pediatric Nonalcoholic Fatty Liver Disease?. Orkin, S; Yodoshi, T; Sun, Q; Fei, L; Meryum, S; Arce-Clachar, AC; Bramlage, K; Beck, AF; Mouzaki, M. Obesity Research. 2021; 29:171-176.

Imaging prediction of islet yield and post-operative insulin requirement in children undergoing total pancreatectomy with islet autotransplantation. Trout, AT; Nolan, HR; Abu-El-Haija, M; Fei, L; Lin, TK; Elder, DA; Nathan, JD. Pancreatology. 2021; 21:269-274.