I am an associate professor of pediatrics and the director of the Neurofibromatosis Program within the Division of Oncology. My clinical focus includes neurofibromatosis, plexiform neurofibromas, malignant peripheral nerve sheath tumors and pediatric solid tumors. My research interests center on developmental therapeutics, functional outcome assessments and preventing neurofibromatosis tumor-related morbidity and mortality.
I received my medical degree from the University of Connecticut School of Medicine. I completed my pediatric residency at Cincinnati Children’s, where I also served as chief resident, followed by a fellowship in pediatric hematology/oncology at Children’s National Hospital in Washington, D.C.
BS: University of Connecticut, 2006
MD: University of Connecticut School of Medicine, 2010
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 2013
Chief Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 2014
Fellowship: Pediatric Hematology / Oncology, Children's National Hospital, 2017
Certifications: General Pediatrics, American Board of Pediatrics, 2013; Pediatric Hematology / Oncology, American Board of Pediatrics, 2019
Neurofibromatosis; plexiform neurofibromas; malignant peripheral nerve sheath tumors; pediatric solid tumors; clinical research
Developmental therapeutics; functional outcome assessments; prevention of tumor-related morbidity and mortality
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Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial. Nature Medicine. 2025; 31(1):105-115.
Cancer risk in adults with pathogenic germline variants in RAS/MAPK genes using genomic ascertainment. Genetics in Medicine. 2026; 28(6):102561.
Wide Ranging Neurobehavioral Phenotype in Individuals With Costello Syndrome. American Journal of Medical Genetics, Part A. 2026; 200(5):1138-1144.
MEK inhibitor-induced dropped head syndrome in pediatrics. Neuro-Oncology Pediatrics. 2026; 2(2):wuag024.
Evolution of Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Opportunities for Prevention and Therapeutic Strategies. Annual Review of Cancer Biology. 2026; 10(1):223-241.
Abstract 2548: Circulating proteomic signatures for subtyping NF1 associated peripheral nerve sheath tumors. Cancer Research. 2026; 86(7_Supplement):2548-2548.
Neurofibromatosis type 1-plexiform neurofibromas: Integrating treatment across pediatric and adult populations. Neuro-Oncology. 2026; 28(4):847-863.
SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST). Clinical Cancer Research. 2026; 32(6):1068-1077.
Rare cancers research: Current state of knowledge and emerging opportunities for prevention and interception. Journal of the National Cancer Institute. 2026.
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