A photo of Andrea M. Gross.

Andrea M. Gross, MD


  • Director, Neurofibromatosis Program, Division of Oncology
  • Associate Professor, UC Department of Pediatrics

About

Biography

I am an associate professor of pediatrics and the director of the Neurofibromatosis Program within the Division of Oncology. My clinical focus includes neurofibromatosis, plexiform neurofibromas, malignant peripheral nerve sheath tumors and pediatric solid tumors. My research interests center on developmental therapeutics, functional outcome assessments and preventing neurofibromatosis tumor-related morbidity and mortality.

I received my medical degree from the University of Connecticut School of Medicine. I completed my pediatric residency at Cincinnati Children’s, where I also served as chief resident, followed by a fellowship in pediatric hematology/oncology at Children’s National Hospital in Washington, D.C.

BS: University of Connecticut, 2006.

MD: University of Connecticut School of Medicine, 2010.

Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 2013.

Chief Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 2014.

Fellowship: Pediatric Hematology / Oncology, Children's National Hospital, 2017.

Certification: General Pediatrics, American Board of Pediatrics, 2013; Pediatric Hematology / Oncology, American Board of Pediatrics, 2019.

Interests

Neurofibromatosis; plexiform neurofibromas; malignant peripheral nerve sheath tumors; pediatric solid tumors; clinical research

Services and Specialties

Interests

Developmental therapeutics; functional outcome assessments; prevention of tumor-related morbidity and mortality

Insurance Information

Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.

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Publications

61430 Dermatologic adverse events in neurofibromatosis patients on MEK inhibitors. Parisi, R; Dhulipalla, S; Widemann, B; Pichard, DC; Gross, A; Weintraub, L. Journal of the American Academy of Dermatology. 2025; 93:ab33.

Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series. Sargen, MR; Fitzhugh, MH; Ko, JS; Close, AG; Horton, SC; Malik, F; Furtado, LV; Bahrami, A; Seynnaeve, BK N; Pappo, AS; Gross, AM; Kaplan, R; Yohe, ME; Berrebi, KG. Pediatric Blood and Cancer. 2025; 72:e31814.

Challenges in Assessing Response in Clinical Trials for Neurofibromatosis Type 1 Plexiform Neurofibromas. Dombi, E; Gross, AM; Widemann, BC; Weiss, BD; Plotkin, SR; Ahlawat, S. Journal of Clinical Oncology. 2025; 43:1843-1844.

Treatment of Cutaneous Neurofibromas in Neurofibromatosis Type 1 With MEK Inhibitor Selumetinib: A Nonrandomized Clinical Trial. Gross, AM; Reid, OH; Baldwin, LA; Cannon, A; Choo-Wosoba, H; Steinberg, SM; Lobbous, M; Wolters, PL; Pichard, DC; Tibery, CM; Dombi, E; Derdak, J; Widemann, BC; Korf, BR. JAMA Dermatology. 2025; 161:533-537.

Anthropometric measurements of children with neurofibromatosis type I: impact of plexiform neurofibroma volume and treatment. Lemberg, KM; Gross, AM; Sproule, LM; Liewehr, DJ; Dombi, E; Baldwin, A; Steinberg, SM; Bornhorst, M; Lodish, M; Blakeley, JO; Widemann, BC. Pediatric Research. 2025; 97:1918-1928.

Consensus recommendations for an integrated diagnostic approach to peripheral nerve sheath tumors arising in the setting of Neurofibromatosis Type 1. Lucas, CG; Gross, AM; Romo, CG; Dehner, CA; Lazar, AJ; Miettinen, M; Pekmezci, M; Quezado, M; Rodriguez, FJ; Stemmer-Rachamimov, A; Viskochil, D; Perry, A; Symposium on Atypical Neurofibroma: State of the S, . Neuro-Oncology. 2025; 27:616-624.

A Pilot Acceptance and Commitment Intervention for Parents of Children With RASopathies. Little, P; Al Ghriwati, N; Siegel, A; Toledo-Tamula, MA; Curlee, MS; Baker, M; Rogge, RD; Yohe, M; Gross, A; Martin, S. Clinical Practice in Pediatric Psychology. 2025; 13:37-48.

A Mixed Methods Study of Medication Adherence in Adults with Neurofibromatosis Type 1 (NF1) on a Clinical Trial of Selumetinib. Curlee, MS; Toledo-Tamula, MA; Baker, M; Wikstrom, D; Harrison, C; Rhodes, A; Fagan, M; Tibery, C; Wolters, PL; Widemann, BC; Gross, AM; Martin, S. Cancers. 2025; 17:295.

Selumetinib in pediatric patients with neurofibromatosis type 1 and plexiform neurofibroma: Propensity score analysis of SPRINT vs. natural history control arm. Adeyemi, A; Gross, AM; Baldwin, A; Dombi, E; Widemann, BC; Sint, KJ. Neuro-Oncology Advances. 2025; 7:vdaf101.

Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial. Gross, AM; O'Sullivan Coyne, G; Dombi, E; Tibery, C; Herrick, WG; Martin, S; Angus, SP; Shern, JF; Rhodes, SD; Foster, JC; Srivastava, AK; Doroshow, JH; Chen, AP; Widemann, BC. Nature Medicine. 2025; 31:105-115.

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