A photo of Michael Grimley.

Michael S. Grimley, MD

  • Medical Director, Division of Bone Marrow Transplantation and Immune Deficiency
  • Professor, UC Department of Pediatrics
I believe that each patient is unique. I use a cooperative approach to treatment, in which I partner with the treatment team, the patient and their family.



I’ve been interested in medicine for as long as I can remember. My medical school experiences with the children solidified my feeling that pediatrics was the area I related to best.

Similarly, my exposure to pediatric and adult hematology/oncology patients and physicians in medical school confirmed that I wanted to work with these patients and colleagues.

As a bone marrow transplant physician, I believe that each patient is unique. I use a cooperative approach to treatment, in which I partner with the treatment team, the patient and their family.

My research involves finding treatments for and prevention of viral infections in immunocompromised patients.

When I’m not treating patients or involved in research, I enjoy spending time with my family.

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A case of treatment-resistant membranous nephropathy associated with graft versus host disease successfully treated with daratumumab. Benoit, SW; Khandelwal, P; Grimley, MS. Pediatric Transplantation. 2022; 26.

Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant. Rubinstein, JD; Lutzko, C; Leemhuis, T; Zhu, X; Pham, G; Ray, L; Thomas, S; Dourson, C; Wilhelm, J; Lane, A; et al. Blood Advances. 2022; 6:2897-2907.

Granulocyte Colony-Stimulating Factor Is Safe and Well Tolerated following Allogeneic Transplantation in Patients with Sickle Cell Disease. Shah, NC; Bhoopatiraju, S; Abraham, A; Anderson, E; Andreansky, M; Bhatia, M; Chaudhury, S; Cuvelier, GD E; Godder, K; Grimley, M; et al. Transplantation and cellular therapy. 2022; 28:174.e1-174.e5.

Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation. Qayed, M; Watkins, B; Gillespie, S; Bratrude, B; Betz, K; Choi, SW; Davis, J; Duncan, C; Giller, R; Grimley, M; et al. Blood Advances. 2022; 6:746-749.

Ruxolitinib for the Treatment of Chronic GVHD and Overlap Syndrome in Children and Young Adults. Wang, YZ M; Teusink-Cross, A; Elborai, Y; Krupski, MC; Nelson, AS; Grimley, MS; Flannery, A; Mehta, PA; Bleesing, JJ; Chandra, S; et al. Transplantation. 2022; 106:412-419.

Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients. Rubinstein, JD; Jodele, S; Heyenbruch, D; Wilhelm, J; Thomas, S; Lutzko, C; Zhu, X; Leemhuis, T; Cancelas, JA; Keller, M; et al. Transplantation and cellular therapy. 2022; 28:116.e1-116.e7.

Early stool microbiome and metabolome signatures in pediatric patients undergoing allogeneic hematopoietic cell transplantation. Elgarten, CW; Tanes, C; Lee, JJ; Danziger-Isakov, LA; Grimley, MS; Green, M; Michaels, MG; Barnum, JL; Ardura, MI; Auletta, JJ; et al. Pediatric Blood and Cancer. 2022; 69.

Case Report: Fatal Complications of BK Virus-Hemorrhagic Cystitis and Severe Cytokine Release Syndrome Following BK Virus-Specific T-Cells. Holland, EM; Gonzalez, C; Levy, E; Valera, VA; Chalfin, H; Klicka-Skeels, J; Yates, B; Kleiner, DE; Hadigan, C; Dave, H; et al. Frontiers in Immunology. 2021; 12.

Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted. Rubinstein, JD; Zhu, X; Leemhuis, T; Pham, G; Ray, L; Emberesh, S; Jodele, S; Thomas, S; Cancelas, JA; Bollard, CM; et al. Blood Advances. 2021; 5:3309-3321.

Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD. Watkins, B; Qayed, M; McCracken, C; Bratrude, B; Betz, K; Suessmuth, Y; Yu, A; Sinclair, S; Furlan, S; Bosinger, S; et al. Journal of Clinical Oncology. 2021; 39:1865-1877.

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