About
Biography
I have been a biomedical researcher for over 13 years and began working at Cincinnati Children’s in 2014. My research aims to identify the underlying biological mechanisms that govern skeletal muscle growth and muscle disorders in children. Ultimately, I strive to make a difference by optimizing muscle health and development in children with muscle weaknesses.
I work with Dr. Roger Cornwall, MD, to study neuromuscular contractures in children with brachial plexus birth injuries. We are examining the biological basis of contractures and exploring nonsurgical interventions to prevent them. Our works have been published in many well-respected journals, including JCI Insight, FASEB Journal and FEBS Letters.
I also have a strong commitment to mentoring undergraduate, graduate and medical students in biomedical research. Their works and contributions have garnered individual awards and led to journal publications. My former trainees have successfully transitioned to industry positions and have also been accepted into medical school programs.
BS: University of Vermont, Burlington, VT, 2007.
MS: James Madison University, Harrisonburg, VA, 2010.
PhD: University of Toledo, Toledo, OH, 2014.
Postdoc: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2019.
Services and Specialties
Orthopaedic Surgery
Interests
Skeletal muscle biology; pediatric muscle disorder
Research Areas
Orthopaedics
Publications
Sexual dimorphisms in skeletal muscle: current concepts and research horizons. Journal of applied physiology (Bethesda, Md. : 1985). 2024; 137:274-299.
The Relative Efficacy of Available Proteasome Inhibitors in Preventing Muscle Contractures Following Neonatal Brachial Plexus Injury. The Journal of Bone and Joint Surgery. 2024; 106:727-734.
The role of sympathetic innervation in neonatal muscle growth and neuromuscular contractures. The Federation of European Biochemical Societies (FEBS) Journal. 2023; 290:4877-4898.
Brachial plexus birth injury and cerebral palsy lead to a common contracture phenotype characterized by reduced functional muscle length and strength. Frontiers in Rehabilitation Sciences. 2022; 3:983159.
NRG/ErbB signaling regulates neonatal muscle growth but not neuromuscular contractures in neonatal brachial plexus injury. FEBS Letters. 2021; 595:655-666.
Timing of proteasome inhibition as a pharmacologic strategy for prevention of muscle contractures in neonatal brachial plexus injury. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021; 35:e21214.
Scientific Advances in the Understanding of Contracture Pathogenesis in Brachial Plexus Birth Injury. 2020; 2:129.
Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle. eLife. 2019; 8:e44876.
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