A photo of Qingnian Goh.

Qingnian Goh, PhD

  • Instructor, UC Department of Orthopedic Surgery

About

Biography

I have been a biomedical researcher for over 13 years and began working at Cincinnati Children’s in 2014. My research aims to identify the underlying biological mechanisms that govern skeletal muscle growth and muscle disorders in children. Ultimately, I strive to make a difference by optimizing muscle health and development in children with muscle weaknesses.

I work with Dr. Roger Cornwall, MD, to study neuromuscular contractures in children with brachial plexus birth injuries. We are examining the biological basis of contractures and exploring nonsurgical interventions to prevent them. Our works have been published in many well-respected journals, including JCI Insight, FASEB Journal and FEBS Letters.

I also have a strong commitment to mentoring undergraduate, graduate and medical students in biomedical research. Their works and contributions have garnered individual awards and led to journal publications. My former trainees have successfully transitioned to industry positions and have also been accepted into medical school programs.

BS: University of Vermont, Burlington, VT, 2007.

MS: James Madison University, Harrisonburg, VA, 2010.

PhD: University of Toledo, Toledo, OH, 2014.

Postdoc: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2019.

Services and Specialties

Orthopaedic Surgery

Interests

Skeletal muscle biology; pediatric muscle disorder

Research Areas

Orthopaedics

Publications

Selected

NRG/ErbB signaling regulates neonatal muscle growth but not neuromuscular contractures in neonatal brachial plexus injury. Ho, BL; Goh, Q; Nikolaou, S; Hu, L; Shay-Winkler, K; Cornwall, R. FEBS Letters. 2021; 595:655-666.

Selected

Timing of proteasome inhibition as a pharmacologic strategy for prevention of muscle contractures in neonatal brachial plexus injury. Goh, Q; Nikolaou, S; Shay-Winkler, K; Emmert, ME; Cornwall, R. FASEB Journal. 2021; 35.

Selected

Scientific advances in the understanding of contracture pathogenesis in brachial plexus birth injury. Goh, Q; Cornwall, R. 2020; 2:1-18.

Selected

Proteasome inhibition preserves longitudinal growth of denervated muscle and prevents neonatal neuromuscular contractures. Nikolaou, S; Cramer, AA W; Hu, L; Goh, Q; Millay, DP; Cornwall, R. JCI insight. 2019; 4.

Selected

Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle. Goh, Q; Song, T; Petrany, MJ; Cramer, AA W; Sun, C; Sadayappan, S; Lee, S; Millay, DP. eLife. 2019; 8.

Selected

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy. Goh, Q; Millay, DP. eLife. 2017; 6.

Selected

Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development. Quinn, ME; Goh, Q; Kurosaka, M; Gamage, DG; Petrany, MJ; Prasad, V; Millay, DP. Nature Communications. 2017; 8.

Selected

Intercellular adhesion molecule-1 expression by skeletal muscle cells augments myogenesis. Goh, Q; Dearth, CL; Corbett, JT; Pierre, P; Chadee, DN; Pizza, FX. Experimental Cell Research. 2015; 331:292-308.

Selected

Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response. Dearth, CL; Goh, Q; Marino, JS; Cicinelli, PA; Torres-Palsa, MJ; Pierre, P; Worth, RG; Pizza, FX. PLoS ONE. 2013; 8.

Selected

Recovery from cycling exercise: effects of carbohydrate and protein beverages. Goh, Q; Boop, CA; Luden, ND; Smith, AG; Womack, CJ; Saunders, MJ. Nutrients. 2012; 4:568-584.