A photo of Paul Horn.

Paul S. Horn, PhD

  • Biostatistician, Division of Neurology
  • Professor, UC Department of Pediatrics



My area of research is statistical analysis and how to apply general statistical methodology to specific pediatric problems. I want to improve statistical analysis in pediatrics to provide more reliable evidence for decision making.

I am interested in providing answers to questions regarding the statistical methodology that applies to pediatric populations, such as appropriate reference ranges. One of my achievements is the development of quantile estimators that are relatively robust for smaller sample sizes.

I am a member of the International Committee for the Clinical and Laboratory Standards Institute. My career spans more 39 years, and I have worked at Cincinnati Children’s since 2013. My research has been published in various respected journals, including Interdisciplinary Neurosurgery, Advanced Techniques and Case Management, Neuroscience, Frontiers in Integrative Neuroscience, Muscle and Nerve, and Neurology.


Large body movements on video polysomnography are associated with daytime dysfunction in children with restless sleep disorder. Liu, WK; Dye, TJ; Horn, P; Patterson, C; Garner, D; Simakajornboon, N. Sleep. 2022; 45.

Topiramate Is Safe for Refractory Neonatal Seizures: A Multicenter Retrospective Cohort Study of Necrotizing Enterocolitis Risk. Vawter-Lee, M; Natarajan, N; Rang, K; Horn, PS; Pardo, AC; Thomas, CW. Pediatric Neurology. 2022; 129:7-13.

Regulating Together: Emotion Dysregulation Group Treatment for ASD Youth and Their Caregivers. Shaffer, RC; Schmitt, LM; Reisinger, DL; Coffman, M; Horn, P; Goodwin, MS; Mazefsky, C; Randall, S; Erickson, C. Journal of Autism and Developmental Disorders. 2022.

EEG Correlates of Active Stopping and Preparation for Stopping in Chronic Tic Disorder. Vera, AZ; Pedapati, EV; Larsh, TR; Kohmescher, K; Miyakoshi, M; Huddleston, DA; Jackson, HS; Gilbert, DL; Horn, PS; Wu, SW. Brain Sciences. 2022; 12.

Pediatric reference intervals for 32 routine biochemical markers using the siemens healthineers atellica® CH assays in healthy children and adolescents. Bohn, MK; Horn, P; League, D; Steele, P; Hall, A; Adeli, K. Clinical Biochemistry. 2022; 99:69-77.

Symptom rates and profile clustering in tuberous sclerosis complex-associated neuropsychiatric disorders (TAND). Alperin, S; Krueger, DA; Franz, DN; Agricola, KD; Stires, G; Horn, PS; Capal, JK. Journal of Neurodevelopmental Disorders. 2021; 13.

A distributed network supports spatiotemporal cerebral dynamics of visual naming. Ervin, B; Buroker, J; Byars, AW; Rozhkov, L; Leach, JL; Horn, PS; Scholle, C; Mangano, FT; Greiner, HM; Holland, KD; et al. Electromyography and Clinical Neurophysiology. 2021; 132:2948-2958.

Profile of Autism Spectrum Disorder in Tuberous Sclerosis Complex: Results from a Longitudinal, Prospective, Multisite Study. Capal, JK; Williams, ME; Pearson, DA; Kissinger, R; Horn, PS; Murray, D; Currans, K; Kent, B; Bebin, M; Northrup, H; et al. Annals of Neurology. 2021; 90:874-886.

Associations between Task-Related Modulation of Motor-Evoked Potentials and EEG Event-Related Desynchronization in Children with ADHD. Ewen, JB; Puts, NA; Mostofsky, SH; Horn, PS; Gilbert, DL. Cerebral Cortex. 2021; 31:5526-5535.

Epilepsy Is Heterogeneous in Early-Life Tuberous Sclerosis Complex. Ihnen, SK Z; Capal, JK; Horn, PS; Griffith, M; Sahin, M; Bebin, EM; Wu, JY; Northrup, H; Krueger, DA. Pediatric Neurology. 2021; 123:1-9.