A photo of Paul Horn.

Biostatistician, Division of Neurology

Professor, UC Department of Pediatrics


Biography & Affiliation


My area of research is statistical analysis and how to apply general statistical methodology to specific pediatric problems. I want to improve statistical analysis in pediatrics to provide more reliable evidence for decision making.

I am interested in providing answers to questions regarding the statistical methodology that applies to pediatric populations, such as appropriate reference ranges. One of my achievements is the development of quantile estimators that are relatively robust for smaller sample sizes.

I am a member of the International Committee for the Clinical and Laboratory Standards Institute. My career spans more 39 years, and I have worked at Cincinnati Children’s since 2013. My research has been published in various respected journals, including Interdisciplinary Neurosurgery, Advanced Techniques and Case Management, Neuroscience, Frontiers in Integrative Neuroscience, Muscle and Nerve, and Neurology.

Research Interests

Robustness; nonparametrics; statistical computing; simulations; reference intervals.

Academic Affiliation

Professor, UC Department of Pediatrics

Research Divisions



PhD: Statistics, Princeton University, Princeton, NJ, 1981.


Evaluation of Posterior Fossa Biometric Measurements on Fetal MRI in the Evaluation of Dandy-Walker Continuum. Nagaraj, UD; Kline-Fath, BM; Horn, PS; Venkatesan, C. American Journal of Neuroradiology. 2021; 42:1716-1721.

Subtraction ictal SPECT co-registered to MRI (SISCOM) patterns in children with temporal lobe epilepsy. Aungaroon, G; Trout, AT; Radhakrishnan, R; Horn, PS; Arya, R; Tenney, JR; Holland, KD; Mangano, FT; Leach, JL; Rozhkov, L; et al. Epilepsy and Behavior. 2021; 121.

Pediatric reference intervals for endocrine markers and fertility hormones in healthy children and adolescents on the Siemens Healthineers Atellica immunoassay system. Bohn, MK; Horn, P; League, D; Steele, P; Hall, A; Adeli, K. Clinical Chemistry and Laboratory Medicine. 2021; 59:1421-1430.

In Silico Predictions of KCNQ Variant Pathogenicity in Epilepsy. Ritter, DM; Horn, PS; Holland, KD. Pediatric Neurology. 2021; 118:48-54.

Relationship between GABA levels and task-dependent cortical excitability in children with attention-deficit/hyperactivity disorder. Harris, AD; Gilbert, DL; Horn, PS; Crocetti, D; Cecil, KM; Edden, RA E; Huddleston, DA; Mostofsky, SH; Puts, NA J. Electromyography and Clinical Neurophysiology. 2021; 132:1163-1172.

Motor cortex modulation and reward in children with attention-deficit/hyperactivity disorder. Detrick, JA; Zink, C; Rosch, KS; Horn, PS; Huddleston, DA; Crocetti, D; Wu, SW; Pedapati, EV; Wassermann, EM; Mostofsky, SH; et al. Brain Communications. 2021; 3.

Brief Report: Intranasal Ketamine in Adolescents and Young Adults with Autism Spectrum Disorder-Initial Results of a Randomized, Controlled, Crossover, Pilot Study. Wink, LK; Reisinger, DL; Horn, P; Shaffer, RC; O'Brien, K; Schmitt, L; Dominick, KR; Pedapati, EV; Erickson, CA. Journal of Autism and Developmental Disorders. 2021; 51:1392-1399.

Features of Menstruation and Menstruation Management in Individuals with Rett Syndrome. Humphrey, KN; Horn, PS; Olshavsky, L; Reebals, L; Standridge, SM. Journal of Pediatric and Adolescent Gynecology. 2021; 34:144-153.

Oral Manifestations and Quality of Life in Children with Tuberous Sclerosis Complex: A Descriptive Study. Gosnell, ES; Krueger, D; Ruck, P; Buff-Lindner, AH; Horn, PS; Griffith, M. Pediatric Dentistry. 2021; 43:140-144.

Implementation of the Mini-Child Tourette Syndrome Impairment Scale: Relationships to Symptom Severity and Treatment Decisions. Garris, JF; Huddleston, DA; Jackson, HS; Horn, PS; Gilbert, DL. Journal of Child Neurology. 2021; 36:288-295.