Paul S. Horn, PhD

Biostatistician, Division of Neurology
Professor, UC Department of Pediatrics

paul.horn@cchmc.org

About

Biography

My area of research is statistical analysis and how to apply general statistical methodology to specific pediatric problems. I want to improve statistical analysis in pediatrics to provide more reliable evidence for decision making.

I am interested in providing answers to questions regarding the statistical methodology that applies to pediatric populations, such as appropriate reference ranges. One of my achievements is the development of quantile estimators that are relatively robust for smaller sample sizes.

I am a member of the International Committee for the Clinical and Laboratory Standards Institute. My career spans more 39 years, and I have worked at Cincinnati Children’s since 2013. My research has been published in various respected journals, including Interdisciplinary Neurosurgery, Advanced Techniques and Case Management, Neuroscience, Frontiers in Integrative Neuroscience, Muscle and Nerve, and Neurology.

Interests

Robustness; nonparametrics; statistical computing; simulations; reference intervals.

Research Areas

Neurology

Publications

In children with attention‐deficit/hyperactivity disorder, less task‐related up‐modulation of motor cortex during response inhibition. Gilbert, DL; Crocetti, D; Horn, PS; Wu, SW; Huddleston, DA; Ehrman, JM; Migneault, KY; Mostofsky, SH. 2025.

Cenobamate's Efficacy for Seizure Treatment in Tuberous Sclerosis Complex. Aungaroon, G; Cooke, A; Ritter, D; Krueger, D; Horn, P; Franz, DN. Pediatric Neurology. 2024; 161:201-207.

Racial, Ethnic, and Socioeconomic Disparities in Pediatric Aquaporin-4-Positive Neuromyelitis Optica Spectrum Disorder. Poisson, KE; Nguyen, L; Horn, PS; Beck, AF; Wu, H; Wesselkamper, K; Ness, JM; Wheeler, YS. Pediatric Neurology. 2024; 161:194-200.

Healthcare provider recognition of pregnancy related risks and management considerations in patients with tuberous sclerosis complex. Rose, M; Ritter, D; Gupta, N; Tolusso, L; Horn, P; Wakefield, E; Glass, J. Orphanet Journal of Rare Diseases. 2024; 19:4.

Examining the feasibility and utility of heart rate variability on intervention outcomes targeting emotion regulation in autism: a brief report. Reisinger, DL; Goodwin, MS; Horn, PS; Schmitt, LM; Coffman, MC; Shaffer, RC. Scientific Reports. 2024; 14:15409.

The impact of genotype on age at loss of ambulation in individuals with Duchenne muscular dystrophy treated with corticosteroids: A single-center study of 555 patients. Zygmunt, A; Wong, B; Moon, D; Horn, P; Rathbun, R; Lambert, J; Bange, J; Rybalsky, I; Reebals, L; Tian, C. Muscle and Nerve. 2024; 70:1053-1061.

Telehealth regulating together pilot trial: emotion regulation intervention for autistic children and adolescents. Coffman, M; Wells, M; Schmitt, LM; Reisinger, DL; Horn, PS; Shaffer, RC. Frontiers in Psychiatry. 2024; 15:1401148.

330P Trends in creatine kinase levels and 10-meter walk-run velocity in pediatric Becker muscular dystrophy treated with glucocorticoid steroids. Zygmunt, A; Vilaisaktipakorn, P; Sharaf, T; Shiuan, Y; Horn, P; Bange, J; Reebals, L; Rybalsky, I; Tian, C. Neuromuscular Disorders. 2024; 43:104441.661.

High-gamma modulation language mapping and cognitive outcomes after epilepsy surgery. Ervin, B; Kargol, C; Byars, AW; Buroker, J; Rozhkov, L; Skoch, J; Mangano, FT; Greiner, HM; Horn, PS; Holland, K; Arya, R. Epilepsia. 2024; 65:3052-3063.

324P A longitudinal study of creatine kinase, creatinine levels, and appendicular lean mass index in pediatric Becker muscular dystrophy. Horn, P; Zygmunt, A; Vilaisaktipakorn, P; Sharaf, T; Shiuan, Y; Rybalsky, I; Reebals, L; Bange, J; Tian, C. Neuromuscular Disorders. 2024; 43:104441.655.