Rulang Jiang, PhD

Biography & Affiliation Education Publications

Visit the Jiang Lab

Member, Division of Developmental Biology

Professor, UC Department of Pediatrics

rulang.jiang@cchmc.org

513-636-3212

Biography & Affiliation

Biography

Rulang Jiang, PhD, is professor of Pediatrics at Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine. Prior to joining Cincinnati Children's in 2011, he was a tenured professor of Biomedical Genetics at University of Rochester School of Medicine and Dentistry where he established and led a continuously NIH-funded program in the areas of craniofacial development and birth defect research from 1999 to 2011. At Cincinnati Children's, he has expanded research program into understanding of musculoskeletal diseases and tissue repair/regeneration. In addition to NIH grant support, his research is supported by the Shriners Hospital for Children.

Research Interests

Genetic basis and developmental mechanisms of congenital craniofacial malformations; tendon development, homeostasis, and heterotopic ossification

Academic Affiliation

Professor, UC Department of Pediatrics

Departments

Plastic Surgery, Developmental Biology

Education

BS: Nanjing Normal University, Nanjing, China, 1984.

MS: Genetics, Chinese Academy of Sciences, Beijing, China, 1987.

PhD: Wesleyan University, Middletown, CT, 1995.

Publications

Liu H, Xu J, Jiang R. Mkx-deficient mice exhibit Hedgehog signaling dependent heterotopic ossification in the Achilles tendons. J Bone Miner Res. 2019 Mar;34(3):557-569.

Liu Z, Li C, Xu J, Lan Y, Liu H, Li X, Maire P, Wang X, Jiang R. Crucial and overlapping roles of Six1 and Six2 in craniofacial development. J Dent Res. 2019 Mar 24:22034519835204.

Xu J, Liu H, Lan Y, Adam M, Clouthier DE, Potter SS, Jiang R. Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. eLife. 2019 Jan 14;8.

Fu X, Xu J, Chaturvedi P, Liu H, Jiang R, Lan Y. Identification of Osr2 Transcriptional target genes in palate development. Journal of Dental Research. 2017;96(12):1451-1458.

Li C, Lan Y, Krumlauf R, Jiang R. Modulating Wnt signaling rescues palate morphogenesis in Pax9 mutant mice. Journal of Dental Research. 2017;96(11):1273-1281.

Kwon H-JE, Jia S, Lan Y, Liu H, Jiang R. Activin and BMP4 signaling converge on Wnt activation during odontogenesis. Journal of Dental Research. 2017;96(10):1145-1152.

Jia S, Kwon H-JE, Lan Y, Zhou J, Liu H, Jiang R. Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Developmental Biology. 2016;420(1):110-119.

Lan Y, Zhang N, Liu H, Xu J, Jiang R. Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development. 2016;143:2344-2355.

Xu J, Liu H, Lan Y, Aronow BJ, Kalinichenko VV, Jiang R. A Shh-Foxf-Fgf18-Shh molecular circuit regulating palate development. PLOS Genetics. 2016;12(1):e1005769.

Lan Y, Xu J, Jiang R. Cellular and Molecular Mechanisms of Palatogenesis. Current Topics in Developmental Biology (Craniofacial Development). 2015;115:59-84.