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A photo of Rulang Jiang.

Member, Division of Developmental Biology

Professor, UC Department of Pediatrics

513-636-3212

Biography & Affiliation

Biography

Rulang Jiang, PhD, is professor of Pediatrics at Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine. Prior to joining Cincinnati Children's in 2011, he was a tenured professor of Biomedical Genetics at University of Rochester School of Medicine and Dentistry where he established and led a continuously NIH-funded program in the areas of craniofacial development and birth defect research from 1999 to 2011. At Cincinnati Children's, he has expanded research program into understanding of musculoskeletal diseases and tissue repair/regeneration. In addition to NIH grant support, his research is supported by the Shriners Hospital for Children.

Research Interests

Genetic basis and developmental mechanisms of congenital craniofacial malformations; tendon development, homeostasis, and heterotopic ossification

Academic Affiliation

Professor, UC Department of Pediatrics

Departments

Plastic Surgery, Developmental Biology

Education

BS: Nanjing Normal University, Nanjing, China, 1984.

MS: Genetics, Chinese Academy of Sciences, Beijing, China, 1987.

PhD: Wesleyan University, Middletown, CT, 1995.

Publications

Requirement of Hyaluronan Synthase-2 in Craniofacial and Palate Development. Lan, Y; Qin, C; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2019; 98:1367-1375.

Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development. Liu, Z; Li, C; Xu, J; Lan, Y; Liu, H; Li, X; Maire, P; Wang, X; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2019; 98:572-579.

Mkx-Deficient Mice Exhibit Hedgehog Signaling-Dependent Ectopic Ossification in the Achilles Tendons. Liu, H; Xu, J; Jiang, R. Journal of Bone and Mineral Research. 2019; 34:557-569.

Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. Xu, J; Liu, H; Lan, Y; Adam, M; Clouthier, DE; Potter, S; Jiang, R. eLife. 2019; 8.

Identification of Osr2 Transcriptional Target Genes in Palate Development. Fu, X; Xu, J; Chaturvedi, P; Liu, H; Jiang, R; Lan, Y. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1451-1458.

Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice. Li, C; Lan, Y; Krumlauf, R; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1273-1281.

Molecular and Cellular Mechanisms of Palate Development. Li, C; Lan, Y; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1184-1191.

Activin and Bmp4 Signaling Converge on Wnt Activation during Odontogenesis. Kwon, HE; Jia, S; Lan, Y; Liu, H; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1145-1152.

Osr1 functions downstream of Hedgehog pathway to regulate foregut development. Han, L; Xu, J; Grigg, E; Slack, M; Chaturvedi, P; Jiang, R; Zorn, AM. Developmental Biology. 2017; 427:72-83.

Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Jia, S; Kwon, HE; Lan, Y; Zhou, J; Liu, H; Jiang, R. Developmental Biology. 2016; 420:110-119.