A photo of M. Christa Krupski.

Member, Division of Bone Marrow Transplantation and Immune Deficiency

Assistant Professor, UC Department of Pediatrics

Board Certified

"I am detail-oriented and love problem-solving. Most of all, I find it rewarding to offer patients with leukemia a chance at a curative approach via bone marrow transplant."

My Biography & Research

Biography

I developed an interest in medicine at a very young age, when I was exposed to several physicians who were very passionate about their work. I was invited to shadow these individuals, and as I observed the incredible work they were doing, my own excitement for the field of medicine grew.

Now, as a hematologist/oncologist specializing in bone marrow transplantation, I enjoy educating patients and families and supporting them as they undergo the transplant. My primary interest is in transplantation for malignancies, such as leukemia.

Cincinnati Children’s has one of the largest bone marrow transplant programs in the country. Our team consists of phenomenal physicians — many of whom are experts in various areas of transplant medicine — and countless support staff who ensure optimal care of our patients and their families.

I am detail-oriented and love problem-solving. Most of all, I find it rewarding to offer patients with leukemia a chance at a curative approach via bone marrow transplant. It is incredibly gratifying to work with children because they are so resilient — they laugh and play, even when they are sick. I am continuously amazed by how tough young children are.

My research interests include complications and adverse effects of bone marrow transplant. One project I am working on is optimizing how we manage mucositis (mouth / throat inflammation and sores) pain post-transplant.

Outside the hospital, my husband and I love international travel and spending time outdoors.

Clinical Interests

Pediatric bone marrow transplant; leukemia; immunotherapy

Academic Affiliation

Assistant Professor, UC Department of Pediatrics

Clinical Divisions

Cancer and Blood Diseases, Bone Marrow Transplantation BMT

Research Divisions

Bone Marrow Transplantation and Immune Deficiency

My Locations

My Education

DO: Kirksville College of Osteopathic Medicine, Kirksville, MO, 2009.

Residency: Pediatrics, University of Louisville, Louisville, KY.

Fellowship: Pediatric Hematology/Oncology, Vanderbilt University, Nashville, TN; Bone Marrow Transplant and Immunodeficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Certification: Pediatrics, 2012; Pediatric Hematology/Oncology, 2017.

My Publications

Selected Publication

Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). Lee, PY; Kellner, ES; Huang, Y; Furutani, E; Huang, Z; Bainter, W; Alosaimi, MF; Stafstrom, K; Platt, CD; Stauber, T; et al. Journal of Allergy and Clinical Immunology. 2020; 145:1664-1672.e10.

Chimeric antigen receptor T-cell therapy in patients with neurologic comorbidities. Rubinstein, JD; Nelson, AS; Krupski, C; O'Brien, W; Taylor, JM; Badgett, TC; Huang, M; Davies, SM; Phillips, CL. Pediatric Blood and Cancer. 2020; 67.

Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors. Holtan, SG; Khera, N; Levine, JE; Chai, X; Storer, B; Liu, HD; Inamoto, Y; Chen, GL; Mayer, S; Arora, M; et al. Blood. 2016; 128:2350-2358.

Use of CD19-directed CAR T-Cell Therapy in an Infant With Refractory Acute Lymphoblastic Leukemia. Breese, EH; Krupski, C; Nelson, AS; Perentesis, JP; Phillips, CL. Journal of Pediatric Hematology/Oncology. 2021; 43:152-154.

Ruxolitinib for the treatment of chronic GVHD and overlap syndrome in children and young adults. Wang, YM; Teusink-Cross, A; Elborai, Y; Krupski, MC; Nelson, AS; Grimley, MS; Flannery, A; Mehta, PA; Bleesing, JJ; Chandra, S; et al. Transplantation. 2021.

Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation. Chandra, S; Chandrakasan, S; Dávila Saldaña, BJ; Bleesing, JJ; Jordan, MB; Kumar, AR; Grimley, MS; Krupski, C; Davies, SM; Khandelwal, P; et al. Journal of Clinical Immunology. 2021; 41:89-98.

CCR5 inhibitor as novel acute graft versus host disease prophylaxis in children and young adults undergoing allogeneic stem cell transplant: results of the phase II study. Khandelwal, P; Fukuda, T; Teusink-Cross, A; Kashuba, AD M; Lane, A; Mehta, PA; Marsh, RA; Jordan, MB; Grimley, MS; Myers, KC; et al. Bone Marrow Transplantation. 2020; 55:1552-1559.

358 A Single Ultra High Dose of Vitamin D is Safe and Feasible in Early Peri-Transplant Period to Prevent Vitamin D Deficiency in Pediatric HSCT Recipients. Wallace, G; Howell, JC; Jodele, S; Myers, KC; Dandoy, CE; El-Bietar, J; Nelson, AS; Teusink-Cross, A; Khandelwal, P; Taggart, CB; et al. Biology of Blood and Marrow Transplantation. 2018; 24:s286-s287.

231 Amphiregulin Modifies the Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN Acute Gvhd Therapy Trials. Holtan, SG; Defor, TE; Howard, A; Pidala, JA; Levine, JE; Wu, JM; Khera, N; Lee, SJ; Bolaños-Meade, J; Ho, VT; et al. Biology of Blood and Marrow Transplantation. 2018; 24:s177-s178.

50 Prediction of Opioid Requirement for Mucositis By Genotype in Children Undergoing Hematopoietic Cell Transplantation. Krupski, MC; Weidner, N; Lane, A; Davies, SM; Teusink-Cross, A; Chandra, S; Lake, KE; Wilkey, A; Bellman, D; Sadhasivam, S; et al. Biology of Blood and Marrow Transplantation. 2017; 23.