I believe that every patient and family is uniquely different. Listening to their story is powerful in determining a diagnosis and treatment approach.
Erinn S. Kellner, MD



I am the current director of the Transition and Adult Immunodeficiency Program within the Division of Allergy and Immunology at Cincinnati Children’s..

I always loved the field of science and understanding why things happened and why someone would become sick. Fortunately, while in college, I worked in a basic immunology and rheumatology lab with some incredible lifelong mentors, Dr. Westley Reeves and Dr. Pui Lee. This experience made me fall in love with the complexity of the immune system.

Later, I found the field of allergy, immunology and immune deficiency and saw patients who had an interesting overlap of both immune deficiency and autoimmunity. This field allowed me the unique opportunity to see patients from childhood through adulthood. I realized then the emerging need for trained experts in the area of adult immune deficiency.

My specialty is in allergy and clinical immunology, specifically immune deficiency, immune dysregulation and eosinophilic conditions. I believe that every patient and family is uniquely different. Listening to their story is powerful in determining a diagnosis and treatment approach. I work closely with other subspecialists at Cincinnati Children’s Hospital Medical Center and feel fortunate to have an amazing diagnostic immunology lab to help with diagnosis and treatment.

During my Allergy and Immunology Fellowship, I was honored to be the Visiting Immunology Scholars Awardee at Icahn School of Medicine at Mount Sinai. I applied through the Immune Deficiency Foundation and was fortunate to be awarded two weeks with one of the world’s leading experts in adult primary immune deficiency, Dr. Charlotte Cunningham-Rundles. She has served as a career model and also an example for the clinic I am developing.

I was also a participant in the Clinical Immunology Society School in Primary Immunodeficiency Diseases, and a participant in the Clinical Immunology Society Diagnostic School in Primary Immunodeficiency, in which I was selected to go to a conference to improve my immunology skills further.

I won the American Academy of Allergy Asthma & Immunology (AAAAI) Fellow-in-Training Basic and the Clinical Immunology Section Abstract Award for my abstract titled “Cellular defects in CVID patients with chronic lung disease in the USIDNET registry.” I gave an oral presentation of this abstract at the 2018 AAAAI national meeting. This same abstract also won the 2018 Fellow Research Award from the Illinois Society of Allergy, Asthma, and Immunology and was later published in the Journal of Clinical Immunology. These experiences set the stage for pursuing further training at Cincinnati Children’s through a Clinical Immunodeficiency Fellowship and becoming faculty of the Division of Allergy and Immunology.

In my research, I am seeking a better understanding of the pathophysiology and treatment options for patients with common variable immunodeficiency who get an underlying interstitial lung disease, called granulomatous-lymphocytic interstitial lung disease.

In my free time, I enjoy cooking, gardening, hiking, traveling and spending time with my husband and my dog.

BS: University of Florida, Gainesville, FL, 2008.

MD: University of South Florida, Tampa, FL, 2012.

Residency: Internal Medicine, University of South Florida, Tampa, FL, 2013-2016.

Fellowship: Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2016-2018.

Fellowship: Clinical Immunodeficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2018-2019.

Certification: Internal Medicine Board, 2016.

Certification: Allergy and Immunology Board, 2018.


Immune deficiency; immune dysregulation; eosinophilic disorders

Services and Specialties

Allergy and Immunology, Eosinophilic Disorders


Immune deficiency; immune dysregulation; eosinophilic disorders; development of chronic lung disease in patients with immune deficiency and dysregulation

Research Areas

Allergy and Immunology

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COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET Report. McDonnell, J; Cousins, K; Younger, ME M; Lane, A; Abolhassani, H; Abraham, RS; Al-Tamemi, S; Aldave-Becerra, JC; Al-Faris, EH; Alfaro-Murillo, A; Lim, XR; Lopes, JP; López, AL; Tarquini, L. Journal of Clinical Immunology. 2024; 44:86.

Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial. Kliewer, KL; Murray-Petzold, C; Collins, MH; Abonia, JP; Bolton, SM; DiTommaso, LA; Martin, LJ; Zhang, X; Mukkada, VA; Putnam, PE; Lyles, JL; Shoda, T; Klion, AD; Rothenberg, ME. The Lancet Gastroenterology and Hepatology. 2023; 8:803-815.

Quality of life is lower in adults labeled with childhood-onset food allergy than in those with adult-onset food allergy. Patel, GB; Kellner, ES; Clayton, E; Chhiba, KD; Alakija, O; Bryce, PJ; Wechsler, JB; Singh, AM. Annals of Allergy, Asthma, and Immunology. 2021; 127:70-75.e2.

Geographic Variability and Pathogen-Specific Considerations in the Diagnosis and Management of Chronic Granulomatous Disease. Prince, BT; Thielen, BK; Williams, KW; Kellner, ES; Arnold, DE; Cosme-Blanco, W; Redmond, MT; Hartog, NL; Chong, HJ; Holland, SM. Pediatric Health, Medicine and Therapeutics. 2020; 11:257-268.

Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). Lee, PY; Kellner, ES; Huang, Y; Furutani, E; Huang, Z; Bainter, W; Alosaimi, MF; Stafstrom, K; Platt, CD; Stauber, T; Chou, J; Geha, RS; Nigrovic, PA; Zhou, Q. Journal of Allergy and Clinical Immunology. 2020; 145:1664-1672.e10.

The Value of Chromosome Analysis to Interrogate Variants in DNMT3B Causing Immunodeficiency, Centromeric Instability, and Facial Anomaly Syndrome Type I (ICF1). Kellner, ES; Rathbun, PA; Marshall, GS; Tolusso, LK; Smolarek, TA; Sun, M; Chandra, S; Bleesing, J; Marsh, RA. Journal of Clinical Immunology. 2019; 39:857-859.

Cellular Defects in CVID Patients with Chronic Lung Disease in the USIDNET Registry. Kellner, ES; Fuleihan, R; Cunningham-Rundles, C; Wechsler, JB; Consortium, US I D N E T. Journal of Clinical Immunology. 2019; 39:569-576.

Allogeneic hematopoietic stem cell transplant outcomes for patients with dominant negative IKZF1/IKAROS mutations. Kellner, ES; Krupski, C; Kuehn, HS; Rosenzweig, SD; Yoshida, N; Kojima, S; Boutboul, D; Latour, S; Barlogis, V; Galambrun, C; Stray-Pedersen, A; Erichsen, HC; Marsh, RA. Journal of Allergy and Clinical Immunology. 2019; 144:339-342.

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