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Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor.
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The Rhesus Macaque Serves As a Model for Human Lateral Branch Nephrogenesis.
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Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.
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Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis.
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Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism.
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