Postnatal alveologenesis depends on FOXF1 signaling in c-KIT1 endothelial progenitor cells.
Ren, X; Ustiyan, V; Guo, M; Wang, G; Bolte, C; Zhang, Y; Xu, Y; Whitsett, JA; Kalin, TV; Kalinichenko, VV.
American Journal of Respiratory and Critical Care Medicine.
2019;
200:1164-1176.
The S52F FOXF1 mutation inhibits STAT3 signaling and causes alveolar capillary dysplasia.
Pradhan, A; Dunn, A; Ustiyan, V; Bolte, C; Wang, G; Whitsett, JA; Zhang, Y; Porollo, A; Hu, Y; Xiao, R; et al.
American Journal of Respiratory and Critical Care Medicine.
2019;
200:1045-1056.
The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice.
Sun, L; Ren, X; Wang, I; Pradhan, A; Zhang, Y; Flood, HM; Han, B; Whitsett, JA; Kalin, TV; Kalinichenko, VV.
Science Signaling.
2017;
10:eaai8583-eaai8583.
FOXF1 maintains endothelial barrier function and prevents edema after lung injury.
Cai, Y; Bolte, C; Le, T; Goda, C; Xu, Y; Kalin, TV; Kalinichenko, VV.
Science Signaling.
2016;
9:ra40-ra40.
FOXF1 Transcription Factor Is Required for Formation of Embryonic Vasculature by Regulating VEGF Signaling in Endothelial Cells.
Ren, X; Ustiyan, V; Pradhan, A; Cai, Y; Havrilak, JA; Bolte, CS; Shannon, JM; Kalin, TV; Kalinichenko, VV.
Circulation Research.
2014;
115:709-720.
FOXM1 Promotes Allergen-Induced Goblet Cell Metaplasia and Pulmonary Inflammation.
Ren, X; Shah, TA; Ustiyan, V; Zhang, Y; Shinn, J; Chen, G; Whitsett, JA; Kalin, TV; Kalinichenko, VV.
Molecular and Cellular Biology.
2013;
33:371-386.
Foxm1 Mediates Cross Talk between Kras/Mitogen-Activated Protein Kinase and Canonical Wnt Pathways during Development of Respiratory Epithelium.
Wang, I; Snyder, J; Zhang, Y; Lander, J; Nakafuku, Y; Lin, J; Chen, G; Kalin, TV; Whitsett, JA; Kalinichenko, VV.
Molecular and Cellular Biology.
2012;
32:3838-3850.
Forkhead Box m1 transcription factor is required for perinatal lung function.
Kalin, TV; Wang, I; Meliton, L; Zhang, Y; Wert, SE; Ren, X; Snyder, J; Bell, SM; Jr, GL; Whitsett, JA; et al.
Proceedings of the National Academy of Sciences of USA.
2008;
105:19330-19335.
Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression.
Malin, D; Kim, I; Boetticher, E; Kalin, TV; Ramakrishna, S; Meliton, L; Ustiyan, V; Zhu, X; Kalinichenko, VV.
Molecular and Cellular Biology.
2007;
27:2486-2498.
Genome Editing for Rare Diseases.
Pradhan, A; Kalin, TV; Kalinichenko, VV.
Current stem cell reports.
2020;
6:41-51.