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Director, Cell Manipulation Laboratory and Translational Development, Translational Core Laboratory
Associate Professor, UC Department of Pediatrics
Regulating human pluripotent stem cell; somatic cell reprogramming in iPSC; human embryonic stem cell physiology and differentiation; hESC; cystic fibrosis
Experimental Hematology and Cancer Biology, Cancer and Blood Diseases
Carolyn M. Lutzko, PhD4/2/2020
BA: University of Guelph, S.Sc. Hon, Molecular Biology and Genetics Guelph, Ontario, Canada 1992.
PhD: University of Toronto, PhD Department of Laboratory Medicine Toronto, Ontario, Canada 1999.
Fellowship: Childrens Hospital Los Angeles Department of Pediatrics Division of Research Immunology/BMT Los Angeles, CA, 1999-2002.
Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium.
Salomonis, N; Dexheimer, PJ; Omberg, L; Schroll, R; Bush, S; Huo, J; Schriml, L; Sui, SH; Keddache, M; Mayhew, C; et al.
Stem Cell Reports.
Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells.
Nayak, RC; Trump, LR; Aronow, BJ; Myers, K; Mehta, P; Kalfa, T; Wellendorf, AM; Valencia, CA; Paddison, PJ; Horwitz, MS; et al.
Journal of Clinical Investigation.
Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy.
Rubinstein, JD; Zhu, X; Lutzko, C; Leemhuis, T; Cancelas, JA; Jodele, S; Bollard, CM; Hanley, PJ; Davies, SM; Grimley, MS; et al.
Mouse models of neutropenia reveal progenitor-stage-specific defects.
Muench, DE; Olsson, A; Ferchen, K; Pham, G; Serafin, RA; Chutipongtanate, S; Dwivedi, P; Song, B; Hay, S; Chetal, K; et al.
EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects.
Rubinstein, JD; Burns, K; Absalon, M; Lutzko, C; Leemhuis, T; Chandra, S; Hanley, PJ; Keller, MD; Davies, SM; Nelson, A; et al.
Pediatric Blood and Cancer.
CD38brightCD8+ T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells.
Khandelwal, P; Chaturvedi, V; Owsley, E; Lane, A; Heyenbruch, D; Lutzko, CM; Leemhuis, T; Grimley, MS; Nelson, AS; Davies, SM; et al.
Biology of Blood and Marrow Transplantation.
Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo.
Trump, LR; Nayak, RC; Singh, AK; Emberesh, S; Wellendorf, AM; Lutzko, CM; Cancelas, JA.
Stem Cells Translational Medicine.
Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives.
Daily, K; Sui, SJ H; Schriml, LM; Dexheimer, PJ; Salomonis, N; Schroll, R; Bush, S; Keddache, M; Mayhew, C; Lotia, S; et al.
Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency.
Nasimuzzaman, M; Lynn, D; Ernst, R; Beuerlein, M; Smith, RH; Shrestha, A; Cross, S; Link, K; Lutzko, C; Nordling, D; et al.
Molecular Therapy-Methods & Clinical Development.
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