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Jaime L. Lopes, PhD

  • Director, Genetics and Genomics Diagnostic Laboratory, Division of Human Genetics
  • Assistant Professor, UC Department of Pediatrics



Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair. Chaudhry, SR; Lopes, J; Levin, NK; Kalpage, H; Tainsky, MA. Cell Death Discovery. 2021; 7.

Most noninvasive prenatal screens failing due to inadequate fetal cell free DNA are negative for trisomy when repeated. Lopes, JL; Lopes, GS; Enninga, EA L; Kearney, HM; Hoppman, NL; Rowsey, RA. Prenatal Diagnosis. 2020; 40:831-837.

Characterizing false-positive fluorescence in situ hybridization results by mate-pair sequencing in a patient with chronic myeloid leukemia and progression to myeloid blast crisis. Lopes, JL; Webley, M; Pitel, BA; Pearce, KE; Smadbeck, JB; Johnson, SH; Vasmatzis, G; Sukov, WR; Greipp, PT; Hoppman, NL; et al. Cancer genetics. 2020; 243:48-51.

Unconventional Diagnosis Based on Somatic Findings through Germ Line Whole-Exome Sequencing. Lopes, JL; Rasmussen, KJ; Mehta, N; Boczek, NJ; Hasadsri, L. Clinical Chemistry. 2020; 66:48-51.

Encyclopedia of Evolutionary Psychological Science. Lopes, J. . : Springer International Publishing; Springer International Publishing; 2020.

FANCM, RAD1, CHEK1 and TP53I3 act as BRCA-like tumor suppressors and are mutated in hereditary ovarian cancer. Lopes, JL; Chaudhry, S; Lopes, GS; Levin, NK; Tainsky, MA. Cancer genetics. 2019; 235-236:57-64.

Whole Exome Sequencing: A Necessary Tool for the Future of Clinical Cancer Care. Chaudhry, S; Lopes, J; Levin, N; Tainsky, M. 2017; 5:1106-1107.

Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability. Stafford, JL; Dyson, G; Levin, NK; Chaudhry, S; Rosati, R; Kalpage, H; Wernette, C; Petrucelli, N; Simon, MS; Tainsky, MA. PLoS ONE. 2017; 12.