Timothy D. Le Cras, PhD

Vascular malformations are disorders in which blood or lymphatic vessels develop abnormally, often causing serious health problems in children. A better understanding these conditions is essential for improving treatments and saving the lives of children with life-threatening vascular malformations or anomalies.

My research focuses on how blood and lymphatic vessels grow and what goes wrong when vascular diseases develop. By studying patient samples and cells, my team works to identify the key biological changes that drive these disorders and to discover new treatment options.

Working with colleagues at Cincinnati Children’s, we have also studied genetic changes that contribute to vascular malformations in children. Our research has helped uncover new approaches for targeted treatment.

A key strength of our work is our close collaboration with physicians at Cincinnati Children’s and other pediatric hospitals. These partnerships allow us to study patient blood samples and gain unique insights into disease processes.

I have more than 30 years of experience in vascular research and have been part of Cincinnati Children’s since 2001. My work has been published in leading medical and scientific journals and is focused on improving the diagnosis and treatment of vascular disorders in children.