Gene therapy with the DWORF micropeptide attenuates cardiomyopathy in mice.
Makarewich, CA; Bezprozvannaya, S; Gibson, AM; Bassel-Duby, R; Olson, EN.
Circulation Research.
2020;
127:1340-1342.
The hidden world of membrane microproteins.
Makarewich, CA.
Experimental Cell Research.
2020;
388:111853-111853.
Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers.
Singh, DR; Dalton, MP; Cho, EE; Pribadi, MP; Zak, TJ; Seflova, J; Makarewich, CA; Olson, EN; Robia, SL.
Journal of Molecular Biology.
2019;
431:4429-4443.
The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
Makarewich, CA; Munir, AZ; Schiattarella, GG; Bezprozvannaya, S; Raguimova, ON; Cho, EE; Vidal, AH; Robia, SL; Bassel-Duby, R; Olson, EN.
eLife.
2018;
7.
MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation.
Makarewich, CA; Baskin, KK; Munir, AZ; Bezprozvannaya, S; Sharma, G; Khemtong, C; Shah, AM; McAnally, JR; Malloy, CR; Szweda, LI; et al.
Cell Reports.
2018;
23:3701-3709.
Mining for Micropeptides.
Makarewich, CA; Olson, EN.
Trends in Cell Biology.
2017;
27:685-696.
Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.
Anderson, DM; Makarewich, CA; Anderson, KM; Shelton, JM; Bezprozvannaya, S; Bassel-Duby, R; Olson, EN.
Science Signaling.
2016;
9:ra119-ra119.
Muscle physiology: A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle.
Nelson, BR; Makarewich, CA; Anderson, DM; Winders, BR; Troupes, CD; Wu, F; Reese, AL; McAnally, JR; Chen, X; Kavalali, ET; et al.
Science.
2016;
351:271-275.
MED12 regulates a transcriptional network of calcium-handling genes in the heart.
Baskin, KK; Makarewich, CA; DeLeon, SM; Ye, W; Chen, B; Beetz, N; Schrewe, H; Bassel-Duby, R; Olson, EN.
JCI insight.
2017;
2.
A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9.
Carroll, KJ; Makarewich, CA; McAnally, J; Anderson, DM; Zentilin, L; Liu, N; Giacca, M; Bassel-Duby, R; Olson, EN.
Proceedings of the National Academy of Sciences of USA.
2016;
113:338-343.