Watch a video to learn more about Halima Moncrieffe, PhD, and her research.
Halima Moncrieffe, PhD, is an immunologist who has basic and translational research interests in mechanisms of autoimmune disease susceptibility and immunopathology. Dr. Moncrieffe studies how genetic and immunological variants contribute to inflammation and response to medication. The term 'idiopathic' in JIA denotes that there is no known cause for this debilitating disease. Dr. Moncrieffe's research helped reveal a putative immunological trigger for childhood arthritis and provides new insights into the complexities of JIA. Dr. Moncrieffe also identified a biomarker (MRP8/14) that is present in the blood of a subgroup of patients with JIA who are more likely to respond to methotrexate treatment. This work has translated from the research laboratory to patients and is available as a clinical test.
Dr. Moncrieffe has national and international leadership roles including as Chair of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) SOP committee, and as an active member of the International Union of Immunological Societies' Clinical Immunology Committee. Dr. Moncrieffe leads workshops on research and leadership, and she is a regularly invited local and international speaker and panelist. Dr. Moncrieffe was selected as a TEDMED Research Scholar for her immunology expertise. Dr. Moncrieffe is an active mentor and her students have continued postgraduate studies, including at Ivy League institutions, to pursue their careers in research, medicine, nursing, and pharmacy.
Precision medicine; functional genomics; health disparities; pediatric autoimmune disease with specialty in juvenile idiopathic arthritis (JIA) and systemic lupus erythematosus (SLE)
Assistant Professor, UC Department of Pediatrics