Jun Ma, PhD

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-7977

Fax 513-636-4317

Email jun.ma@cchmc.org

Molecular mechanisms of gene regulation and embryonic development
Research performed by Dr. Ma’s team focuses on understanding developmental processes at a quantitative and systems level. They aim to establish quantitative models—with predictive power—of how embryonic patterns emerge in a manner that is proportional to embryo size. They perform experimental studies to facilitate model building, and use models to make predictions for experimental validations. They use Drosophila (fruit fly) embryos for their studies. The research by Dr. Ma’s team was supported by grants from the National Institutes of Health and the National Science Foundation.

BS: Peking University, 1978-1982.

PhD: Harvard University, Cambridge, MA, 1983-1988 (degree awarded 1990).

View PubMed Publications

Wu H, Manu Jiao R, Ma J. Temporal and spatial dynamics of scaling-specific features of a gene regulatory network in Drosophila. Nat Commun. 2015.

He F, Wei C, Wu H, Cheung D, Jiao R, Ma J. Fundamental origins and limits for scaling a maternal morphogen gradient. Nat Commun. 2015;6:6679.

Liu J, Ma J. Dampened regulates the activating potency of Bicoid and the embryonic patterning outcome in Drosophila. Nat Commun. 2013;4:2968.

Liu J, Ma J. Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos. Nat Cell Biol. 2011 Jan;13(1):22-9.

He F, Wen Y, Deng J, Lin X, Lu LJ, Jiao R, Ma J. Probing intrinsic properties of a robust morphogen gradient in Drosophila. Dev Cell. 2008 Oct;15(4):558-67.