Kana Mizuno, PhD

Member, Clinical Pharmacology
Assistant Professor, UC Department of Pediatrics

kana.mizuno@cchmc.org

About

PhD: Kyoto University, Kyoto, Japan, 2012.

MS: Kyoto University, Kyoto, Japan, 2009.

BS: Tokyo University of Science, Chiba, Japan, 2007.

Research Areas

Clinical Pharmacology

Publications

Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines. Yi, JS; Perla, S; Huang, Y; Mizuno, K; Giordano, FJ; Vinks, AA; Bennett, AM. Cardiovascular Drugs and Therapy. 2022; 36:589-604.

Eculizumab precision-dosing algorithm for thrombotic microangiopathy in children and young adults undergoing HSCT. Mizuno, K; Dandoy, CE; Teusink-Cross, A; Davies, SM; Vinks, AA; Jodele, S. Blood Advances. 2022; 6:1454-1463.

Test-dose pharmacokinetics guided melphalan dose adjustment in reduced intensity conditioning allogeneic transplant for non-malignant disorders. Chandra, S; Mizuno, K; Zhao, J; Davies, SM; Marsh, RA; Fukuda, T; Setchell, KD R; Vinks, AA; Mehta, PA. British Journal of Clinical Pharmacology. 2022; 88:115-127.

Paperspray Ionization Mass Spectrometry as a Tool for Predicting Real-Time Optimized Dosing of the Chemotherapeutic Drug Melphalan. Zhao, J; Sharat, C; Mehta, PA; Mizuno, K; Vinks, AA; Setchell, KD R. Journal of Applied Laboratory Medicine. 2021; 6:625-636.

Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab. Jodele, S; Dandoy, CE; Lane, A; Laskin, BL; Laskin, B; Teusink-Cross, A; Myers, KC; Wallace, G; Nelson, AS; Nelson, A; et al. Blood. 2020; 135:1049-1057.

Pharmacokinetics and Pharmacodynamics Estimation of Eculizumab in a 2-Year-Old Girl With Atypical Hemolytic Uremic Syndrome: A Case Report With 4-Year Follow-Up. Saida, K; Fukuda, T; Mizuno, K; Ogura, M; Kamei, K; Ito, S. Frontiers in Pediatrics. 2019; 7.

Micafungin antifungal prophylaxis in children undergoing HSCT: can we give higher doses, less frequently? A pharmacokinetic study. Chandra, S; Fukuda, T; Mizuno, K; Davies, SM; Teusink-Cross, A; Tarin, R; Marsh, RA; Vinks, AA; Mehta, PA. Journal of Antimicrobial Chemotherapy. 2018; 73:1651-1658.

Population Pharmacokinetics and Optimal Sampling Strategy for Model-Based Precision Dosing of Melphalan in Patients Undergoing Hematopoietic Stem Cell Transplantation. Mizuno, K; Dong, M; Fukuda, T; Chandra, S; Mehta, PA; McConnell, S; Anaissie, EJ; Vinks, AA. Clinical Pharmacokinetics. 2018; 57:625-636.