Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance–Weighted Meta-Analysis.
Kawai, VK; Shi, M; Feng, Q; Chung, CP; Liu, G; Cox, NJ; Jarvik, GP; Lee, MT M; Hebbring, SJ; Harley, JB; et al.
Arthritis and Rheumatology.
2020;
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A polygenic and phenotypic risk prediction for polycystic ovary syndrome evaluated by phenomewide association studies.
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Journal of Clinical Endocrinology and Metabolism.
2020;
105:1918-1936.
Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization.
Robinson, JR; Carroll, RJ; Bastarache, L; Chen, Q; Mou, Z; Wei, W; Connolly, JJ; Mentch, F; Sleiman, P; Crane, PK; et al.
World Journal of Surgery.
2020;
44:84-94.
A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR.
Safarova, MS; Satterfield, BA; Fan, X; Austin, EE; Ye, Z; Bastarache, L; Zheng, N; Ritchie, MD; Borthwick, KM; Williams, MS; et al.
npj Genomic Medicine.
2019;
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GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
Namjou, B; Lingren, T; Huang, Y; Parameswaran, S; Cobb, BL; Stanaway, IB; Connolly, JJ; Mentch, FD; Benoit, B; Niu, X; et al.
BMC Medicine.
2019;
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Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network.
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The American Journal of Human Genetics.
2019;
105:588-605.
The eMERGE genotype set of 83,717 subjects imputed to similar to 40 million variants genome wide and association with the herpes zoster medical record phenotype.
Stanaway, IB; Hall, TO; Rosenthal, EA; Palmer, M; Naranbhai, V; Knevel, R; Namjou-Khales, B; Carroll, RJ; Kiryluk, K; Gordon, AS; et al.
Genetic Epidemiology.
2019;
43:63-81.
A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Mosley, JD; Feng, Q; Wells, QS; Van Driest, SL; Shaffer, CM; Edwards, TL; Bastarache, L; Wei, W; Davis, LK; McCarty, CA; et al.
Nature Communications.
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Probing the Virtual Proteome to Identify Novel Disease Biomarkers.
Mosley, JD; Benson, MD; Smith, JG; Melander, O; Ngo, D; Shaffer, CM; Ferguson, JF; Herzig, MS; McCarty, CA; Chute, CG; et al.
Circulation.
2018;
138:2469-2481.
A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
Patel, ZH; Lu, X; Miller, D; Forney, CR; Lee, J; Lynch, A; Schroeder, C; Parks, L; Magnusen, AF; Chen, X; et al.
Human Molecular Genetics.
2018;
27:2392-2404.