I’m an epidemiologist with applied research interests in pediatric cardiology, nutrition, and the impact of the developing infant intestinal microbiome on growth and early development. My areas of methodical research interest include applying and developing analytical methods for microbial metagenomic next-generation sequence data, dietary assessment and analysis methodology, predictive modeling and causal inference.
My interest in research stems from a desire to improve the health outcomes of children. I strive for the thoughtful application of epidemiologic research methods and biostatistics to support evidence-based care.
I collaborate broadly as a quantitative methodologist in health sciences research and lead the Biostatistics, Epidemiology and Research Design (BERD) Core of the Center for Clinical & Translational Science & Training (CCTST), the Microbial Metagenomics Analysis Center, and the Biostatistics Service for the Heart Institute Research Core at Cincinnati Children’s. My current work is largely focused on supporting these core services.
I have been a researcher for over 15 years and began working at Cincinnati Children’s in 2014.
PhD: Columbia University, New York, 2009.
MPhil: Columbia University, New York, 2009.
MS: University of Cincinnati, Cincinnati, OH, 2008.
BS: Miami University, Oxford, OH, 2004.
Pediatric cardiology; microbial metagenomics
Application and development of analytical methods for microbial metagenomic next-generation sequence data; dietary assessment and analysis methodology; predictive modeling; causal inference
Biostatistics and Epidemiology
Looking at the full picture, using topic modeling to observe microbiome communities associated with disease. 2024; 1:1-11.
Impact of Functional Status at the Time of Transplant on Short-Term Pediatric Lung Transplant Outcomes in the USA. Lung: an international journal on lungs, airways and breathing. 2024; 202:775-783.
Prediction of cardiac surgery associated acute kidney injury using response to loop diuretic and urine neutrophil gelatinase associated lipocalin. Pediatric Nephrology. 2024; 39:3597-3606.
Abstract 4140698: CASE MANAGERS AND PEER SUPPORT GROUPS (CAMPS) FOR PROPHYLAXIS ADHERENCE IN RHEUMATIC HEART DISEASE. Circulation. 2024; 150:a4140698.
Characteristics and Outcomes of Children and Young Adults With Sepsis Requiring Continuous Renal Replacement Therapy: A Comparative Analysis From the Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK). Critical Care Medicine. 2024; 52:1686-1699.
Immunomodulatory Effect of Selective Cytopheretic Device (SCD) on Neutrophil-to-Lymphocyte Ratio (NLR) and Hematologic Parameters from Multiple AKI Trials. Journal of the American Society of Nephrology : JASN. 2024; 35:10.1681/asn.2024az0471n4.
Isosorbide DiNitrate Effect on Hemodynamic Profile, Liver Stiffness, and Exercise Tolerance in Fontan Circulation (The NEET Clinical Trial). Pediatric Cardiology. 2024; 45:1389-1397.
The Association Between Vasopressin and Adverse Kidney Outcomes in Children and Young Adults Requiring Vasopressors on Continuous Renal Replacement Therapy. Critical Care Explorations. 2024; 6:e1156.
Continuous Kidney Replacement Therapy and Survival in Children and Young Adults: Findings From the Multinational WE-ROCK Collaborative. American Journal of Kidney Diseases. 2024; 84:406-415.e1.
Infectious Complications in Critically Ill Children and Young Adults Receiving Continuous Kidney Replacement Therapy. Journal of the American Society of Nephrology : JASN. 2024; 35:10.1681/asn.20240ynq81c1.