A photo of William O'Brien.

Director, Pediatric Neuroradiology Fellowship, Department of Radiology and Medical Imaging

Associate Professor, UC Department of Radiology


My Biography & Research


William T. O’Brien, Sr, DO, received a Bachelor of Science degree in Environmental Engineering from the U.S. Military Academy at West Point and attended medical school at the Philadelphia College of Osteopathic Medicine. He completed a radiology residency at David Grant USAF Medical Center at Travis Air Base, California and fellowships in neuroradiology and pediatric neuroradiology at the University of Cincinnati and Cincinnati Children’s Hospital Medical Center. During his military career, Dr. O’Brien served in a variety of academic roles, to include department chairman and radiology residency program director. He joined the faculty at Cincinnati Children’s Hospital Medical Center in 2017 as the director of the Pediatric Neuroradiology Fellowship Program.

Clinical Interests

Pediatric neuroimaging

Academic Affiliation

Associate Professor, UC Department of Radiology


Radiology, Radiology

My Education

DO: Philadelphia College of Osteopathic Medicine, Philadelphia, PA.

Residency: David Grant USAF Medical Center, Travis AFB, CA.

Fellowships: Neuroradiology, University of Cincinnati, Cincinnati, OH; Pediatric Neuroradiology, Cincinnati Children's Hospital, Cincinnati, OH.

Certifications: Diagnostic Radiology; Neuroradiology.

My Publications

O’Brien WT. Top 3 Differentials in Radiology: A Case Review, 2nd ed. New York: Thieme, 2017.

Kirkland JD, Dahlin B, O’Brien WT. The transclival artery – a variant persistent carotid-basilar arterial anastomosis not previously reported. J Neurointerv Surg. 2017;9(3):e11.

O’Brien WT, Hamelin S, Weitzel EK. The preoperative sinus CT: avoiding a CLOSE call with surgical complications. Radiology. 2016;281:10-21.

O’Brien WT, Shen P, Lee P. The dens: normal development, developmental variants and anomalies, and traumatic injuries. J Clin Imaging Sci. 2015;5(2):1-6.

O’Brien WT. Top 3 Differentials in Neuroradiology: A Case Review. New York: Thieme, 2014.

Betts A, O’Brien WT, Davies BW, Youssef OH. A systematic approach to CT evaluation of orbital trauma. Emerg Radiol. 2014;21(5):511-31.

O’Brien WT. Imaging of primary posterior fossa brain tumors in children. J Am Osteopath Coll Radiol. 2013;2(3):2-12.

O’Brien WT, Vagal A, Cornelius R. Applications of computed tomography angiography (CTA) in neuroimaging. Semin Roentgenol. 2010;45(2):107-115.

O’Brien WT, Lattin GE Jr, Thompson KA. Lemierre syndrome: an all-but-forgotten disease. AJR Am J Roentgenol. 2006;187(3):w324.

Takahashi M, Hackney D, Zhang G, Wehrli S, Wright A, O’Brien WT, Uematsu H, Wehrli F, Selzer M. Magnetic resonance microimaging of intra-axonal water diffusion in live excised lamprey spinal cord. PNAS Proc Natl Acad Sci. 2002;99(25):16192-96.