A photo of Ernest Pedapati.

Assistant Professor, UC Department of Psychiatry and Behavioral Neuroscience


Board Certified

My Biography & Research


Dr. Pedapati specializes in the treatment of neuropsychiatric disease associated with ASD, genetic and other neurodevelopmental disorders including interdisciplinary treatment planning and advanced medication management. Prior to his faculty appointment, he had clinical and research training under Craig Erickson, MD, and pediatric transcranial magnetic stimulation under Donald Gilbert, MD, MS.

In 2013, the PI was successful in designing and obtaining IRB approval and competitive funding for a TMS project through the American Academy of Child & Adolescent Psychiatry Pilot Research Award and currently completing the study, "Cortical Plasticity in Adolescent Depression" which attempts to use TMS to determine whether abnormal neuroplasticity can be quantified in adolescent depression.

In his final year of residency, he applied and secured a highly competitive institutional mentor career development award (Procter Scholar) to support 90% time dedicated to independent research activities including obtaining preliminary data on TMS measures of cortical plasticity in ASD and the development of an implicit false belief task of social cognition for future TMS modulation. In addition he continues to be an active subinvestigator extensively contributing to NIH R01 project examining TMS measures of motor physiology in ADHD pioneered the use of SICI as a biomarker in ADHD and measurement of cortical plasticity in healthy youth. 

Clinical Interests

Neurodevelopmental disorders; autism spectrum disorders; fragile X; genetic disorders; schizophrenia

Research Interests

Transcranial magnetic stimulation; transcranial direct current stimulation; TMS; TDCS; EEG; autism; fragile x; eye tracking; electrophysiology.

Academic Affiliation

Assistant Professor, UC Department of Psychiatry and Behavioral Neuroscience

Clinical Divisions

Neurology, Psychiatry, Tuberous Sclerosis

Research Divisions

Neurology, Psychiatry

My Locations

My Education

MD: University of Massachusetts, Worcester, MA, 2009.

Residency: Pediatrics/Adult Psychiatry/Child Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Certification: Pediatrics, American Board of Pediatrics.

My Publications

Selected Publication

Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Goel, A; Cantu, DA; Guilfoyle, J; Chaudhari, GR; Newadkar, A; Todisco, B; de Alba, D; Kourdougli, N; Schmitt, LM; Pedapati, E; et al. Nature Neuroscience. 2018; 21:1404-1411.

Early behavioral and developmental interventions in ADNP-syndrome: A case report of SWI/SNF-related neurodevelopmental syndrome. Shillington, A; Pedapati, E; Hopkin, R; Suhrie, K. Molecular Genetics and Genomic Medicine. 2020; 8.

Examination of correlates to health-related quality of life in individuals with fragile X syndrome. Coffman, MC; Shaffer, RC; Schmitt, LM; Dominick, KC; Pedapati, E; Wang, A; Berry-Kravis, E; Tartaglia, N; Erickson, CA. Brain Sciences. 2020; 10:213-213.

Pediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome. Fitzpatrick, SE; Schmitt, LM; Adams, R; Pedapati, EV; Wink, LK; Shaffer, RC; Sage, J; Weber, JD; Dominick, KC; Erickson, CA. Journal of Autism and Developmental Disorders. 2020; 50:1056-1063.

Atypical Social Attention and Emotional Face Processing in Autism Spectrum Disorder: Insights From Face Scanning and Pupillometry. Reisinger, DL; Shaffer, RC; Horn, PS; Hong, MP; Pedapati, EV; Dominick, KC; Erickson, CA. Frontiers in Integrative Neuroscience. 2020; 13.

The relationship between expressive language sampling and clinical measures in fragile X syndrome and typical development. Shaffer, RC; Schmitt, L; Thurman, AJ; Abbeduto, L; Hong, M; Pedapati, E; Dominick, K; Sweeney, J; Erickson, C. Brain Sciences. 2020; 10:66-66.

Differentiating social preference and social anxiety phenotypes in fragile X syndrome using an eye gaze analysis: a pilot study. Hong, MP; Eckert, EM; Pedapati, EV; Shaffer, RC; Dominick, KC; Wink, LK; Sweeney, JA; Erickson, CA. Journal of Neurodevelopmental Disorders. 2019; 11.

Motor cortex facilitation: a marker of attention deficit hyperactivity disorder co-occurrence in autism spectrum disorder. Pedapati, EV; Mooney, LN; Wu, SW; Erickson, CA; Sweeney, JA; Shaffer, RC; Horn, PS; Wink, LK; Gilbert, DL. Translational Psychiatry. 2019; 9.

Pharmacologic Interventions for Irritability, Aggression, Agitation and Self-Injurious Behavior in Fragile X Syndrome: An Initial Cross-Sectional Analysis. Eckert, EM; Dominick, KC; Pedapati, EV; Wink, LK; Shaffer, RC; Andrews, H; Choo, T; Chen, C; Kaufmann, WE; Tartaglia, N; et al. Journal of Autism and Developmental Disorders. 2019; 49:4595-4602.

Auditory EEG Biomarkers in Fragile X Syndrome: Clinical Relevance. Ethridge, LE; De Stefano, LA; Schmitt, LM; Woodruff, NE; Brown, KL; Tran, M; Wang, J; Pedapati, EV; Erickson, CA; Sweeney, JA. Frontiers in Integrative Neuroscience. 2019; 13.