Ernest Pedapati, MD, MS, FAAP
- Assistant Professor, UC Department of Psychiatry and Behavioral Neuroscience
- Board Certified
About
Biography
I specialize in the treatment of neuropsychiatric diseases associated with ASD, genetic, and other neurodevelopmental disorders, including interdisciplinary treatment planning and advanced medication management. Prior to my faculty appointment, I received clinical and research training under Craig Erickson, MD, and pediatric transcranial magnetic stimulation under Donald Gilbert, MD, MS.
In 2013, I successfully designed and obtained IRB approval and competitive funding for a TMS project through the American Academy of Child & Adolescent Psychiatry Pilot Research Award. I am currently completing the study, "Cortical Plasticity in Adolescent Depression," which aims to use TMS to determine whether abnormal neuroplasticity can be quantified in adolescent depression.
During my final year of residency, I applied for and secured a highly competitive institutional mentor career development award (Procter Scholar), which allowed me to dedicate 90% of my time to independent research activities. This included obtaining preliminary data on TMS measures of cortical plasticity in ASD and developing an implicit false belief task of social cognition for future TMS modulation. Additionally, I continue to be an active subinvestigator, extensively contributing to an NIH R01 project examining TMS measures of motor physiology in ADHD. I pioneered the use of SICI as a biomarker in ADHD and the measurement of cortical plasticity in healthy youth.
MD: University of Massachusetts, Worcester, MA, 2009.
Residency: Pediatrics/Adult Psychiatry/Child Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Certification: Pediatrics, American Board of Pediatrics.
Interests
Neurodevelopmental disorders; autism spectrum disorders; fragile X; genetic disorders; schizophrenia
Services and Specialties
Neurology, Psychiatry, Tuberous Sclerosis
Interests
Transcranial magnetic stimulation; transcranial direct current stimulation; TMS; TDCS; EEG; autism; fragile x; eye tracking; electrophysiology.
Research Areas
Neurology, Psychiatry
Locations (2)
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Nature Neuroscience. 2018; 21:1404-1411.
Expert Clinician Certainty in Diagnosing Autism Spectrum Disorder in 16-30-Month-Olds: A Multi-site Trial Secondary Analysis. Journal of Autism and Developmental Disorders. 2024; 54:393-408.
Neuropsychiatric feature-based subgrouping reveals neural sensory processing spectrum in female FMR1 premutation carriers: A pilot study. Frontiers in Integrative Neuroscience. 2023; 17:898215.
Altered frontal connectivity as a mechanism for executive function deficits in fragile X syndrome. Molecular Autism. 2022; 13:47.
Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome. ACS Chemical Neuroscience. 2022; 13:3389-3402.
Brief Report: Telehealth Satisfaction Among Caregivers of Pediatric and Adult Psychology and Psychiatry Patients with Intellectual and Developmental Disability in the Wake of Covid-19. Journal of Autism and Developmental Disorders. 2022; 52:5253-5265.
Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome. Journal of Neurodevelopmental Disorders. 2022; 14:52.
Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome. Communications Biology. 2022; 5:442.
THALAMOCORTICAL DYSRHYTHMIA AS A UNIFYING MODEL OF NEUROPSYCHIATRIC AND NEUROSENSORY DYSFUNCTION IN FRAGILE X SYNDROME. Journal of the American Academy of Child and Adolescent Psychiatry. 2022; 61:s275-s276.
82.1 Case Studies in Precision Medicine in Syndromic Intellectual Development Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 2022; 61:s114.
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