A photo of Quishen Pang.

Member, Division of Experimental Hematology & Cancer Biology

Professor, UC Department of Pediatrics

513-636-1152

513-636-3768

Biography & Affiliation

Clinical Interests

Signal transduction in Fanconi anemia and its evolution to leukemia.

Academic Affiliation

Professor, UC Department of Pediatrics

Divisions

Experimental Hematology and Cancer Biology, Cancer and Blood Diseases

Education

PhD: Oregon State University, Corvallis, OR, 1993.

Postdoctoral Fellow: Oregon Health Sciences University, Portland, OR, 2000.

Publications

The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis. Abe, H; Alavattam, KG; Hu, Y; Pang, Q; Andreassen, PR; Hegde, RS; Namekawa, SH. Current Biology. 2020; 30:408-420.e5.

The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance. Nie, Y; Li, Y; Li, X; Wilson, AF; Pang, Q. Stem Cell Research and Therapy. 2019; 10.

Inactivation of the NHEJ activity of DNA-PKcs prevents fanconi anemia pre-leukemic HSC expansion. Chatla, S; Wilson, AF; Pang, Q. International Journal of Stem Cells. 2019; 12:457-462.

Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation. Chatla, S; Du, W; Wilson, AF; Meetei, AR; Pang, Q. Stem Cell Research. 2019; 40:101550-101550.

Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization. Liu, W; Du, W; Shang, X; Wang, L; Evelyn, C; Florian, MC; Ryan, MA; Rayes, A; Zhao, X; Setchell, K; et al. Leukemia. 2019; 33:749-761.

A small molecule p53 activator attenuates Fanconi anemia leukemic stem cell proliferation. Du, W; Li, X; Wilson, AF; Pang, Q. Stem Cell Research and Therapy. 2018; 9.

A non-myeloablative conditioning approach for long-term engraftment of human and mouse hematopoietic stem cells. Du, W; Liu, W; Mizukawa, B; Shang, X; Sipple, J; Wunderlich, M; Geiger, H; Davies, S; Mulloy, J; Pang, Q; et al. Leukemia. 2018; 32:2041-2046.

CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice. Abe, H; Alavattam, KG; Kato, Y; Castrillon, DH; Pang, Q; Andreassen, PR; Namekawa, SH. Human Molecular Genetics. 2018; 27:1136-1149.

Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell Proliferation. Li, X; Wilson, AF; Du, W; Pang, Q. Stem Cell Reports. 2018; 10:339-346.

In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell Homeostasis. Sertorio, M; Du, W; Amarachintha, S; Wilson, A; Pang, Q. Stem Cell Reports. 2017; 8:1242-1255.