A photo of Quishen Pang.

Member, Division of Experimental Hematology & Cancer Biology

Professor, UC Department of Pediatrics



Biography & Affiliation

Clinical Interests

Signal transduction in Fanconi anemia and its evolution to leukemia.

Academic Affiliation

Professor, UC Department of Pediatrics


Experimental Hematology and Cancer Biology, Cancer and Blood Diseases


PhD: Oregon State University, Corvallis, OR, 1993.

Postdoctoral Fellow: Oregon Health Sciences University, Portland, OR, 2000.


The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis. Abe, H; Alavattam, KG; Hu, Y; Pang, Q; Andreassen, PR; Hegde, RS; Namekawa, SH. Current Biology. 2020; 30:408-420.e5.

The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance. Nie, Y; Li, Y; Li, X; Wilson, AF; Pang, Q. Stem Cell Research and Therapy. 2019; 10.

Inactivation of the NHEJ activity of DNA-PKcs prevents fanconi anemia pre-leukemic HSC expansion. Chatla, S; Wilson, AF; Pang, Q. International Journal of Stem Cells. 2019; 12:457-462.

Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation. Chatla, S; Du, W; Wilson, AF; Meetei, AR; Pang, Q. Stem Cell Research. 2019; 40:101550-101550.

Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization. Liu, W; Du, W; Shang, X; Wang, L; Evelyn, C; Florian, MC; Ryan, MA; Rayes, A; Zhao, X; Setchell, K; et al. Leukemia. 2019; 33:749-761.

A small molecule p53 activator attenuates Fanconi anemia leukemic stem cell proliferation. Du, W; Li, X; Wilson, AF; Pang, Q. Stem Cell Research and Therapy. 2018; 9.

A non-myeloablative conditioning approach for long-term engraftment of human and mouse hematopoietic stem cells. Du, W; Liu, W; Mizukawa, B; Shang, X; Sipple, J; Wunderlich, M; Geiger, H; Davies, S; Mulloy, J; Pang, Q; et al. Leukemia. 2018; 32:2041-2046.

CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice. Abe, H; Alavattam, KG; Kato, Y; Castrillon, DH; Pang, Q; Andreassen, PR; Namekawa, SH. Human Molecular Genetics. 2018; 27:1136-1149.

Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell Proliferation. Li, X; Wilson, AF; Du, W; Pang, Q. Stem Cell Reports. 2018; 10:339-346.

In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell Homeostasis. Sertorio, M; Du, W; Amarachintha, S; Wilson, A; Pang, Q. Stem Cell Reports. 2017; 8:1242-1255.