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Assistant Professor, UC College of Pharmacy

513-558-7749

Biography & Affiliation

Research Interests

Pediatric neuro-oncology; blood-brain barrier; brain tumorigenesis; genetic drivers

Academic Affiliation

Assistant Professor, UC College of Pharmacy

Department

Pharmacy

Education

BS: Biochemistry, Syracuse University, Syracuse, NY, 2002.

PhD: Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY, 2010.

Postdoctoral Fellowship: Pediatric Neuro-Oncology, St. Jude Children's Research Hospital, Memphis, TN, 2016.

Publications

Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q. Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017;95(2):309-325.

Kawauchi D, Ogg RJ, Liu L, Shih DJH, Finkelstein D, Murphy BL, Rehg JE, Korshunov A, Calabrese C, Zindy F, Phoenix T, Kawaguchi Y, Gronych J, Gilbertson RJ, Lichter P, Gajjar A, Kool M, Northcott PA, Pfister SM, Roussel MF. Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells. Oncogene. 2017.

Phoenix TN, Patmore DM, Boop S, Boulos N, Jacus M, Patel YT, Roussel MF, Finkelstein D, Goumnerova L, Perreault S, Wadhwa E, Cho YJ, Stewart CF, Gilbertson RJ. Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. Cancer Cell. 2016;29(4):508-22.

Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R, White E, Tang B, Orisme W, Gupta K, Rusch M, Chen X, Li Y, Nagahawhatte P, Hedlund E, Finkelstein D, Wu G, Shurtleff S, Easton J, Boggs K, Yergeau D, Vadodaria B, Mulder HL, Becksfort J, Gupta P, Huether R, Ma J, Song G, Gajjar A, Merchant T, Boop F, Smith AA, Ding L, Lu C, Ochoa K, Zhao D, Fulton RS, Fulton LL, Mardis ER, Wilson RK, Downing JR, Green DR, Zhang J, Ellison DW, Gilbertson RJ. C11orf95- RELA fusions drive oncogenic NF-kB signalling in ependymoma. Nature. 2014;506(7489):451-5.

Robinson G, Parker M, Kranenberg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Lei W, Zhu X, Chalhoub N, Baker SJ, Huether R, Wang J, Wu G, Rusch M, Hong X, Becksford J, Gupta P, Ma J, Easton J, Pounds S, Zhao D, Gajjar A, Kawauchi D, Roussel MF, Finkelstein D, Ellison DW, Fulton LL, Dooling DJ, Ochoa K, Mardis ER, Wilson RK, Downing JR, Zhang J, Gilbertson RJ. Novel Mutations Target Distinct Subgroups of Medulloblastoma. Nature. 2012;488(7409):43-8.

Phoenix TN, Temple S. Spred1, a Negative Regulator of MAPK-ERK, is Enriched in CNS Germinal Zones, Dampens NSC Proliferation and Maintains Neuroepithelial Structure. Genes & Development. 2010;24(1):45-56 (Featured Cover Image).

Shen Q, Wang Y, Dimos JT, Fasano CA, Phoenix TN, Lemischka IR, Ivanova NB, Stifani S, Morrisey EE, Temple S. The Timing of Cortical Neurogenesis is Encoded Within Lineages of Individual Progenitor Cells. Nature Neuroscience. 2006;9(6):743-751.