A photo of James A. Reagor.

James A. Reagor, MPS, CCP, FPP

  • Director, Department of Cardiovascular Perfusion
  • Director, Joint Pediatric Heart Care Program, Department of Cardiovascular Perfusion
  • Associate Professor, UC Department of Surgery
I feel privileged to work with children, never losing sight of the attention to detail necessary to care for the youngest and smallest patients impacted by cardiovascular disease.
James A. Reagor, MPS, CCP, FPP

About

Biography

As a perfusionist, I assist surgical teams during cardiac, pulmonary and other various surgeries that require cardiopulmonary bypass, mechanical circulatory support, autotransfusion or hyperthermic intraperitoneal chemotherapy.

There are many more questions than answers in the field of perfusion. That’s why I’ve devoted my career to the development of evidence-based solutions that reduce variation in this practice. I am particularly interested in understanding the technical and scientific aspects of pediatric cardiopulmonary bypass. I’m also focused on developing the PediPERForm Learning Network to improve quality in pediatric and congenital perfusion.

For my work in the mission field, I was recognized in 2012 with the American Society of Extracorporeal Technology (AmSECT) Excellence in Perfusion Award.

I feel privileged to work with children, never losing sight of the attention to detail necessary to care for the youngest and smallest patients impacted by cardiovascular disease.

Services and Specialties

Research Areas

Publications

Evaluating the need for magnesium administration following cardioplegic arrest with del Nido cardioplegia solution. Whittaker Striker, C; Reagor, JA. Journal of Extra-Corporeal Technology. 2025; 57:9-13.

Hemostatic derangements associated with cardiopulmonary bypass predict outcomes in pediatric patients undergoing corrective heart surgery. Todd, K; Hogue, SJ; Tweddell, JS; Reagor, JA; Mullins, E; Block, MG; Rosenfeldt, L; Francisco, B; Jodele, S; Sharma, BK; Lane, A; Slusher, C; Kharnaf, M; Morales, DL S; Palumbo, JS. Journal of Thrombosis and Haemostasis. 2025; 23:492-503.

Recommendations for centers performing pediatric heart surgery in the United States. Backer, CL; Overman, DM; Dearani, JA; Romano, JC; Tweddell, JS; Kumar, SR; Marino, BS; Bacha, EA; Jaquiss, RD B; Zaidi, AN; Cohen, MI; McElhinney, DB; Parra, DA; Pasquali, SK. Journal of Thoracic and Cardiovascular Surgery. 2023; 166:1782-1820.

Exogenous nitric oxide delivery protects against cardiopulmonary bypass-associated acute kidney injury: Histologic and serologic evidence from an ovine model. Greenberg, JW; Hogue, S; Raees, MA; Ahmed, HF; Abplanalp, WA; Guzman-Gomez, A; Abdelhamed, Z; Thangappan, K; Reagor, JA; Rose, JE; Goldstein, SL; Zafar, F; Morales, DL S; Cooper, DS. Journal of Thoracic and Cardiovascular Surgery. 2023; 166:e164-e173.

Recommendations for Centers Performing Pediatric Heart Surgery in the United States. Backer, CL; Overman, DM; Dearani, JA; Romano, JC; Tweddell, JS; Ram Kumar, S; Marino, BS; Bacha, EA; Jaquiss, RD B; Zaidi, AN; Cohen, MI; McElhinney, DB; Parra, DA; Pasquali, SK. World Journal for Pediatric and Congenital Hearth Surgery. 2023; 14:642-679.

Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation. Tweddell, JS; Kharnaf, M; Zafar, F; Riggs, KW; Reagor, JA; Monia, BP; Revenko, A; Leino, DG; Owens, AP; Martin, JK; Gourley, B; Rosenfeldt, L; Palumbo, JS. Blood Advances. 2023; 7:1404-1417.

Absolute Versus Relative Near-Infrared Spectroscopy in Pediatric Cardiac Patients. Iliopoulos, I; Cooper, DS; Reagor, JA; Koh, W; Goldstein, BH; Khoury, PR; Morales, DL S; Batlivala, S. Pediatric Critical Care Medicine. 2023; 24:204-212.

A Murine Model of Veno-Arterial Extracorporeal Membrane Oxygenation. Kharnaf, M; Hogue, S; Wilkes, Z; Reagor, JA; Leino, DG; Gourley, B; Rosenfeldt, L; Ma, Q; Devarajan, P; Palumbo, JS; Tweddell, JS; Zafar, F. ASAIO Journal. 2022; 68:e243-e250.

In Response. Reagor, JA. Journal of Extra-Corporeal Technology. 2022; 54:162-163.

Highlights of the Sixteenth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion. Morales, DL S; Lorts, A; Greenberg, JW; Reagor, JA; Ündar, A. World Journal for Pediatric and Congenital Hearth Surgery. 2022; 13:217-219.

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