A photo of Laura B. Ramsey.

Assistant Professor, UC Department of Pediatrics

513-803-8963

Biography & Affiliation

Biography

Dr. Laura Ramsey completed her undergraduate work in 2004, receiving her BS in chemistry at the University of Northern Iowa in Cedar Falls, IA. She then joined the Molecular, Cellular, Developmental Biology & Genetics Program at the University of Minnesota in Minneapolis, MN, where she studied the role of B cell receptor signaling in autoimmunity and leukemia.

After defending her thesis and receiving her PhD in 2009, Dr. Ramsey began her postdoctoral training with Dr. Mary Relling at St. Jude Children's Research Hospital in Memphis, TN. There she studied pharmacogenomics, and identified genetic variants associated with clearance of the drug methotrexate.

Dr. Ramsey is a member of the Clinical Pharmacogenetics Implementation Consortium (CPIC), and led the 2014 update of the CPIC guideline regarding SLCO1B1 and simvastatin-induced myopathy.

Clinical Interests

Pharmacogenetics; pharmacogenomics

Academic Affiliation

Assistant Professor, UC Department of Pediatrics

Departments

Clinical Pharmacology, Pharmacy Research

Education

PhD: University of Minnesota, Minneapolis, MN, 2009.

BS: University of Northern Iowa, Cedar Falls, IA, 2004.

Publications

Pharmacogenetics of treating pediatric anxiety and depression. Ramsey, LB; Bishop, JR; Strawn, JR. Pharmacogenomics. 2019; 20:867-870.

Thyroid Function Screening in Children and Adolescents With Mood and Anxiety Disorders. Luft, MJ; Aldrich, SL; Poweleit, E; Prows, CA; Martin, LJ; DelBello, MP; Keeshin, BR; Ramsey, LB; Strawn, JR. Journal of Clinical Psychiatry. 2019; 80.

Interpreting and Implementing Clinical Pharmacogenetic Tests: Perspectives From Service Providers. Hachad, H; Ramsey, LB; Scott, SA. Clinical Pharmacology and Therapeutics. 2019; 106:298-301.

CYP2C19-Guided Escitalopram and Sertraline Dosing in Pediatric Patients: A Pharmacokinetic Modeling Study. Strawn, JR; Poweleit, EA; Ramsey, LB. Journal of Child and Adolescent Psychopharmacology. 2019; 29:340-347.

Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive Disorders. Poweleit, EA; Aldrich, SL; Martin, LJ; Hahn, D; Strawn, JR; Ramsey, LB. Journal of Child and Adolescent Psychopharmacology. 2019; 29:348-361.

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models. Karol, SE; Janke, LJ; Panetta, JC; Ramsey, LB; Cai, X; Payton, MA; Jenkins, DA; Evans, WE; Relling, MV. PLoS ONE. 2019; 14:e0216328-e0216328.

Delayed methotrexate clearance in patients with acute lymphoblastic leukemia concurrently receiving dasatinib. Ramsey, LB; Mizuno, T; Vinks, AA; O'Brien, MM. Pediatric Blood and Cancer. 2019; 66:e27618-e27618.

Racial Differences in Escitalopram/Citalopram-Related Weight Gain in Children and Adolescents: A Natural Language Processing-Based Electronic Medical Record Study. Ramsey, LB; Aldrich, SL; Poweleit, E; Prows, CA; Martin, LJ; Strawn, JR. Journal of Child and Adolescent Psychopharmacology. 2019; 29:162-163.

Influence of CYP2C19 Metabolizer Status on Escitalopram/Citalopram Tolerability and Response in Youth With Anxiety and Depressive Disorders. Aldrich, SL; Poweleit, EA; Prows, CA; Martin, LJ; Strawn, JR; Ramsey, LB. Frontiers in Pharmacology. 2019; 10.

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma. Rahrmann, EP; Wolf, NK; Otto, GM; Heltemes-Harris, L; Ramsey, LB; Shu, J; Larue, RS; Linden, MA; Rathe, SK; Starr, TK; et al. Molecular cancer research : MCR. 2019; 17:567-582.