Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
Melgar, K; Walker, MM; Jones, LM; Bolanos, LC; Hueneman, K; Wunderlich, M; Jiang, J; Wilson, KM; Zhang, X; Sutter, P; et al.
Science Translational Medicine.
2019;
11:eaaw8828-eaaw8828.
Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease.
Rawat, R; Starczynowski, DT; Ntziachristos, P.
Current Opinion in Cell Biology.
2019;
58:85-94.
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.
Smith, MA; Choudhary, GS; Pellagatti, A; Choi, K; Bolanos, LC; Bhagat, TD; Gordon-Mitchell, S; Von Ahrens, D; Pradhan, K; Steeples, V; et al.
Nature Cell Biology.
2019;
21:640-650.
Chronic immune response dysregulation in MDS pathogenesis.
Barreyro, L; Chlon, TM; Starczynowski, DT.
Blood.
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132:1553-1560.
KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.
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Blood Advances.
2018;
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Chronic innate immune signaling results in ubiquitination of splicing machinery.
Culver-Cochran, AE; Starczynowski, DT.
Cell Cycle.
2018;
17:407-409.
TRAF6 Mediates Basal Activation of NF-kappa B Necessary for Hematopoietic Stem Cell Homeostasis.
Fang, J; Muto, T; Kleppe, M; Bolanos, LC; Hueneman, KM; Walker, CS; Sampson, L; Wellendorf, AM; Chetal, K; Choi, K; et al.
Cell Reports.
2018;
22:1250-1262.
Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in Macrophages.
Kong, F; Liu, Z; Jain, VG; Shima, K; Suzuki, T; Muglia, LJ; Starczynowski, DT; Pasare, C; Bhattacharyya, S.
Journal of immunology (Baltimore, Md. : 1950).
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199:3654-3667.
GMP-ing to Spatial Conclusions about Emergency and Leukemic Myelopoiesis.
Niederkorn, M; Starczynowski, DT.
Cell Stem Cell.
2017;
20:579-581.
Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome.
Varney, ME; Choi, K; Bolanos, L; Christie, S; Fang, J; Grimes, LH; Maciejewski, JP; Inoue, J; Starczynowski, DT.
Leukemia.
2017;
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