A photo of Heidi Sucharew.

Heidi J. Sucharew, PhD


  • Biostatistician, Division of Biostatistics and Epidemiology
  • Associate Professor, UC Department of Pediatrics

About

Biography

I’m a biostatistician and researcher with interest in, and passion for, developing latent variable and prediction models of biomedical data. For more than 18 years, I’ve used these modeling techniques to help scientists and clinicians better understand and predict certain health problems. More specifically, I focus on developing alternative statistical approaches and novel applications that contribute to the advancement of knowledge in stroke, infant neurobehavioral outcomes and the health effects of environmental toxicants.

Over the course of my career, I’ve been fortunate to work with many talented and successful researchers. During my graduate studies at the University of Cincinnati, I worked closely with my advisor and mentor, Dr. Paul Succop, who specialized in structural equation modeling (SEM). This work launched my extensive experience and training in latent variable modeling and SEM techniques.

My ongoing research activities include:

  • Developing prediction models for recurrent stroke
  • Developing prediction models for post-stroke dementia
  • Validating and refining the stroke triage scale (CSTAT)
  • Assessing post-stroke healthcare utilization
  • Estimating stroke outcomes using data from electronic medical records

I helped develop the National Institutes of Health Stroke Scale (NIHSS) item profiles, which showed that the latent class analysis method of evaluating NIHSS items provides a viable alternative to summarizing prognostic information. Compared with using the raw NIHSS total score, this approach may better forecast functional outcomes and death. Our results were successfully validated in subsequent studies.

My work also includes the development of infant neurobehavioral patterns. The NICU Network Neurobehavioral Summary (NNNS) results in 13 summary measures, making an overall exam response difficult to interpret. Our approach was shown to be useful in this study and the proposed algorithm for assigning profile membership to infants in other studies.

Since joining Cincinnati Children’s in 2010, I’ve enjoyed developing my research while collaborating with investigators on multidisciplinary research teams and providing education and training to junior faculty, students and fellows.

Publications

Co-exposure to manganese and lead and pediatric neurocognition in East Liverpool, Ohio. Martin, KV; Sucharew, H; Dietrich, KN; Parsons, PJ; Palmer, CD; Wright, R; Amarasiriwardena, C; Smith, DR; Haynes, EN. Environmental Research. 2021; 202.

Deriving Place of Residence, Modified Rankin Scale, and EuroQol-5D Scores from the Medical Record for Stroke Survivors. Sucharew, H; Kleindorfer, D; Khoury, JC; Alwell, K; Haverbusch, M; Stanton, R; Demel, S; De Los Rios La Rosa, F; Ferioli, S; Jasne, A; et al. Cerebrovascular Diseases. 2021; 50:567-573.

Isolated Third Cranial Nerve Palsy in Pituitary Apoplexy: Case Report and Systematic Review. Rosso, M; Ramaswamy, S; Sucharew, H; Vagal, A; Anziska, Y; Levine, SR. Journal of Stroke and Cerebrovascular Diseases. 2021; 30.

Differential Impact of Home Nurse Contact After Discharge by Financial Strain, Primary Care Access, and Medical Complexity. Auger, KA; Sucharew, HJ; Simmons, JM; Shah, SS; Kahn, RS; Beck, AF; H2O Trial Study Group, . Hospital pediatrics. 2021; 11:791-800.

Respiratory Colonization and Short-Term Temporal Changes in the Urinary Metabolome of Children. Ambroggio, L; Florin, TA; Williamson, K; Pfefferman, C; Wagner, BD; Yeomans, L; Kim, JH; Sucharew, H; Macaluso, M; Ruddy, RM; et al. Metabolites. 2021; 11.

Racial Differences in Atrial Cardiopathy Phenotypes in Ischemic Stroke Patients. Kamel, H; Alwell, K; Kissela, BM; Sucharew, HJ; Woo, D; Flaherty, M; Ferioli, S; Demel, SL; Moomaw, CJ; Walsh, K; et al. Neurology. 2021.

Can non-contrast head CT and stroke severity be used for stroke triage? A population-based study. Kircher, C; Humphries, A; Kleindorfer, D; Alwell, K; Sucharew, H; Moomaw, CJ; Mackey, J; De Los Rios La Rosa, F; Kissela, B; Adeoye, O. American Journal of Emergency Medicine. 2020; 38:2650-2652.

Effect of Parental Adverse Childhood Experiences and Resilience on a Child's Healthcare Reutilization. Shah, AN; Auger, KA; Sucharew, HJ; Mangeot, C; Childress, K; Haney, J; Shah, SS; Simmons, JM; Beck, AF. Journal of hospital medicine (Online). 2020; 15:645-651.

Effect of COVID-19 on Emergent Stroke Care: A Regional Experience. Hsiao, J; Sayles, E; Antzoulatos, E; Stanton, RJ; Sucharew, H; Broderick, JP; Demel, SL; Flaherty, ML; Grossman, AW; Kircher, C; et al. Stroke. 2020; 51:e2111-e2114.

Potential Impact of C-STAT for Prehospital Stroke Triage up to 24 Hours on a Regional Stroke System. Li, JL; McMullan, JT; Sucharew, H; Broderick, JP; Katz, B; Schmit, P; Adeoye, O. Prehospital Emergency Care. 2020; 24:500-504.