Michael G. Sherenian, MD, MS
- Assistant Professor, UC Department of Pediatrics
- michael.sherenian@cchmc.org
- Board Certified
About
Biography
Allergies are the most common health conditions among children throughout the United States. Researching the mechanisms behind allergic reactions is essential for reducing mortality rates and alleviating the symptoms of allergies for children nationwide.
My research focuses on studying and assessing the pathogenesis of allergic ailments, especially atopic dermatitis and its connection with clotting. My colleagues and I are attempting to determine the association between blood clotting and the development of allergic diseases. I also have research interests in asthma, fibrosis, food allergies, allergic rhinitis and the genetic foundation of allergic reactions.
I first became interested in these research topics during my fellowship when examining how an essential regulator of fibrinolysis affected asthma function in children. In terms of patient care, my specialty is caring for patients with allergic disorders, including atopic dermatitis, food allergies, allergic rhinitis and asthma.
I was drawn to working with children who have these conditions. Seeing how I could significantly improve children's quality of life by helping them manage their allergic reactions and alleviate their symptoms is inspiring. In 2015, I received a Pediatrics Board certification after completing my residency at the Cincinnati Children's Hospital Medical Center. By 2018, I achieved my allergy and immunology board certification. I have received K12 funding grants starting in 2018 to continue my research. In addition, in 2020, I received the American Academy of Allergy, Asthma and Immunology Faculty Development Award.
My research has been published in respected journals, such as Allergy, Asthma and Clinical Immunology, Annals of Allergy, Asthma and Immunology, Pediatrics and Journal of Allergy and Clinical Immunology-In Practice.
BS: Cornell University, Ithaca, NY 2008
MD: Drexel University College of Medicine, Philadelphia, PA, 2012.
MS: Northwestern University, Chicago, IL, 2018.
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2012-2015.
Fellowship: Allergy and Immunology, Ann and Robert H. Lurie Children's Hospital of Chicago/Northwestern University, Chicago, IL, 2015-2018.
Pediatrics Board Certification: 2015.
Allergy and Immunology Board Certification: 2018.
Interests
Atopic dermatitis (eczema); asthma; food allergies; allergic rhinitis; urticaria
Services and Specialties
Allergy and Immunology
Interests
Atopic dermatitis (eczema); asthma; food allergies; allergic rhinitis; fibrosis; genetic basis of allergic disease
Research Areas
Asthma
Insurance Information
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Publications
The Effect of Subcutaneous German Cockroach Immunotherapy (SCIT) on Nasal Allergen Challenge (NAC) and Cockroach-specific Antibody Responses Among Urban Children and Adolescents. Journal of Allergy and Clinical Immunology. 2023; 151.
Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings. PLoS Genetics. 2023; 19.
Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial. The Lancet. 2022; 400:502-511.
LB1033 Thrombin contributes to atopic dermatitis pathogenesis and staphylococcus aureus skin colonization in children. Journal of Investigative Dermatology. 2022; 142.
Longitudinal atopic dermatitis endotypes: An atopic march paradigm that includes Black children. Journal of Allergy and Clinical Immunology. 2022; 149:1702-1710.e4.
2 Precision Medicine. Allergy Essentials. 2022.
Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis. Clinical and Experimental Allergy. 2021; 51:666-673.
On the surface: Skin microbial exposure contributes to allergic disease. Annals of Allergy, Asthma and Immunology. 2020; 125:628-638.
Events in Normal Skin Promote Early-Life Atopic Dermatitis-The MPAACH Cohort. Journal of Allergy and Clinical Immunology: In Practice. 2020; 8:2285-2293.e6.
The Mechanisms of Atopic Dermatitis to Asthma in Children (MPAACH) Cohort: Novel Atopic Dermatitis Endotypes. Journal of Allergy and Clinical Immunology. 2020; 145.
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